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Introduction Extraction Production
Carbazole structure
Chemical Name:
Skf 20091;CARBAZOLE;usafek-600;USAF ek-600;'LGC' (2409);9H-CARBAZOLE;Diphenylimid;Dibenzopyrrol;Carbazole 96%;DIPHENYLIMIDE
Molecular Formula:
Formula Weight:
MOL File:

Carbazole Properties

Melting point:
243-246 °C(lit.)
Boiling point:
355 °C(lit.)
vapor pressure 
400 mm Hg ( 323 °C)
refractive index 
1.6192 (estimate)
Flash point:
220 °C
storage temp. 
acetone: soluble50mg/mL
Crystalline Powder, Flakes, or Chunks
Beige-yellow or beige-brownish
Water Solubility 
<0.1 g/100 mL at 19 ºC
Stable. Combustible. Incompatible with strong oxidizing agents, nitrogen oxides, potassium hydroxide.
CAS DataBase Reference
86-74-8(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
Carbazole (86-74-8)
  • Risk and Safety Statements
Signal word  Warning
Hazard statements  H410-H351-H413-H315-H319-H335-H336-H373-H400
Precautionary statements  P501a-P201-P202-P260-P264-P273-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P308+P313-P391-P405-P501-P280-P281-P261-P305+P351+P338
Hazard Codes  Xn,N,T
Risk Statements  22-36/37/38-40-50/53-63-43-23/24/25-45-67-68-51/53
Safety Statements  26-36-60-61-36/37-24/25-23-53-45-36/37/39
RIDADR  UN 2811 6.1/PG 3
WGK Germany  2
RTECS  FE3150000
Hazard Note  Harmful
HazardClass  9
PackingGroup  III
HS Code  29339990
Toxicity LD50 orally in rats: >5 g/kg (Eagle, Carlson)

Carbazole price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 46100 Carbazole VETRANAL 86-74-8 250mg-r $46.3 2019-12-02 Buy
Sigma-Aldrich 1096702 Carprofen Related Compound A United States Pharmacopeia (USP) Reference Standard 86-74-8 50mg $1117.2 2019-12-02 Buy
TCI Chemical C0032 Carbazole >97.0%(GC) 86-74-8 25g $26 2019-12-02 Buy
TCI Chemical C0032 Carbazole >97.0%(GC) 86-74-8 100g $76 2019-12-02 Buy
Alfa Aesar A11448 Carbazole, 95% 86-74-8 50g $25.8 2019-12-02 Buy

Carbazole Chemical Properties,Uses,Production


Carbazole and its derivatives are a class of important nitrogen-containing heterocyclic compounds possessing various unique properties and biological activity.
Carbazole is a colorless small scale crystal, insoluble in water and inorganic acid, slightly soluble in ethanol, ether, acetone, benzene (in high temperature), soluble in chloroform, glacial acetic acid, carbon disulfide, pyridine and furfural, etc. It has intense fluorescence and prolonged phosphorescence under ultraviolet light.


Sulfuric acid method
Dissolve crude anthracene in chlorobenzene or other solvents to remove soluble phenanthrenes, quinones, etc. Insoluble anthracene and carbazoles are then reacted with concentrated sulfuric acid, and then carbazole sulfate is generated departing from the anthracene. The carbazole sulfate is hydrolyzed, filtered and dried to obtain carbazole.

Solvent-rectification method
Dissolve crude anthracene with heavy benzene, and remove soluble phenanthrene, quinone and other substances. Insoluble anthracene and carbazole are rectified in a rectification tower to obtain a mixture containing 85 to 90% of carbazole with a yield of 65%.

Pyridine solvent method
Dissolve crude anthracene with heavy benzene, and remove soluble phenanthrene, quinone and other substances. Then pyridine is used as a solvent to filter off insoluble anthracene at 90°C, and the filtrate is then crystallized to obtain crude carbazole. The crude carbazole can be treated with chlorobenzene or other solvents to obtain carbazole with yield of 97 to 99%.


a. Graebe-Ullmann:
Diazotization from amino diphenylamine, and nitrogen gas heated off to generate carbazole. Reported by Graebe and Ullmann in 1896.
b. Bucherer:
Co-thermal reaction of aryl hydrazine and naphthol in the presence of sodium bisulfite. Reported by Bucherer in 1904.
c. Borsche Drechsel:
Hydrazone is synthesized by condensation of Benzoquinone and cyclohexanone, and the latter cyclized to tetrahydrocarbazole under acidic conditions and then catalyzed by dehydrogenation to generate carbazole. Reported by Drechsel and Borsche in 1868 and 1904 respectively.

Thanks to the development of the catalytic dehydrogenation method, the Borsche method has become a carbazole synthetic route with simple operation, mild conditions, low cost and high yield, and has a high industrial production value.
Because of its unique structure and physicochemical properties, carbazole has aroused great interest among researchers. In recent years, novel monoand poly-substituted carbazole derivatives have been found to have good anti-tumor and anti-convulsant activities, showing broad application prospects. The demand for carbazole and its derivatives has been increasing. In the last decade of the 20th century, a large number of novel precious metals and transition metal catalysts have been used in the synthesis of carbazoles and their derivatives, which greatly enriched the synthetic methods and lay the foundation of synthesizing more complex carbazole derivatives. Nowadays, not only carbazole, but tens of thousands of carbazole derivatives are synthesized by new methods, and are widely used in the pharmaceutical and dye industries.

Chemical Properties

white crystals or light brown powder


Important dye intermediate. Used in making photographic plates sensitive to ultraviolet light. Reagent for lignin, carbohydrates, and formaldehyde.


A white crystalline compound used in the manufacture of dyestuffs.


carbazole: A white crystalline compoundfound with anthracene,C12H9N; m.p. 238°C; b.p. 335°C. It isused in the manufacture of dyestuffs.

General Description

White crystals, plates, leaflets or light tan powder. Sublimes readily. Exhibits strong fluorescence and long phosphorescence on exposure to ultraviolet light.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Carbazole is an extremely weak base. Carbazole is incompatible with strong oxidizing agents. Carbazole reacts with nitrogen oxides. Potassium hydroxide fusion yields a salt.


Possible carcinogen.

Fire Hazard

Flash point data for Carbazole are not available; however, Carbazole is probably combustible.

Safety Profile

intraperitoneal route. A flammable liquid.

Purification Methods

Dissolve carbazole (60g) in conc H2SO4 (300mL), extract with three 200mL portions of *benzene, then stir this into 1600mL of an ice-water mixture. The precipitate is filtered off, washed with a little water, dried, recrystallised from *benzene and then from pyridine/*benzene [Feldman et al. J Am Chem Soc 73 4341 1951]. It has also been recrystallised from EtOH or toluene, sublimed in vacuum, zone-refined, and purified by TLC. [UV: Armarego in Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 158 1971, Beilstein 20/8 V 9.]

Carbazole Preparation Products And Raw materials

Raw materials

Preparation Products

Carbazole Suppliers

Global( 324)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21686 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 22633 55
Mainchem Co., Ltd.
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AB PharmaTech,LLC
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Tianjin Zhongxin Chemtech Co., Ltd.
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career henan chemical co
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Shenzhen Nexconn Pharmatechs Ltd
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View Lastest Price from Carbazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-08-16 Carbazole
US $0.00 / KG 1KG 98% 10 Xinxiang Runyu Material Co., Ltd.
2018-08-09 Carbazole
US $2.00 / KG 1KG 99% customise career henan chemical co

Carbazole Spectrum

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