ChemicalBook >> CAS DataBase List >>Telomycin
Telomycin
- CAS No.
- 19246-24-3
- Chemical Name:
- Telomycin
- Synonyms
- A-128;Nsc235069;Telomycin;Antibiotic 128;A 128-HYP, A 128-OP;18H-Dipyrrolo[2,1-C:2',1'-o][1,4,7,10,13,16,19,22,25]oxaoctaazacyclooctacosine;N-(L-βAsp-L-Ser-)Cyclo(L-Thr*-L-aThr-L-Ala-Gly-L-t3Hyp-3-(1H-indole-3-yl)Dha-β-methyl-L-Trp-4,4-dimethyl-L-aThr-L-c3Hyp-);L-Proline, L-β-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-(3S)-3-hydroxy-L-prolyl-α,β-didehydrotryptophyl-β-methyl-L-tryptophyl-(3S)-3-hydroxy-L-leucyl-3-hydroxy-, (11→3)-lactone, (3R)-;L-Proline, L-.beta.-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-trans-3-hydroxy-L-prolyl-erythro-3-hydroxy-L-leucyl-.beta.-methyl-L-tryptophyl-.alpha.,.beta.-didehydro-L-tryptophyl-cis-3-hydroxy-, .beta.1-lactone
- CBNumber:
- CB4882750
- Molecular Formula:
- C59H77N13O19
- Molecular Weight:
- 1272.33
- MDL Number:
- MFCD01682741
- MOL File:
- 19246-24-3.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
| alpha | D28 -133° (c = 1 in 2:1 methanol-water) |
|---|---|
| Boiling point | 850.94°C (rough estimate) |
| Density | 1.1263 (rough estimate) |
| refractive index | 1.6700 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble; Water: slightly soluble |
| form | A solid |
| pka | 2.41±0.10(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | 21YB614QLY |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in mice (mg/kg): >1000 orally, i.v., i.p., i.m. (Tisch) |
|---|
Telomycin price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28137 | Telomycin | 19246-24-3 | 500μg | $432 | 2024-03-01 | Buy |
| Cayman Chemical | 28137 | Telomycin | 19246-24-3 | 2.5mg | $1400 | 2024-03-01 | Buy |
| Usbiological | T2425 | Telomycin | 19246-24-3 | 500ug | $582 | 2021-12-16 | Buy |
| TRC | T170830 | Telomycin | 19246-24-3 | 1000μg | $735 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013088 | TELOMYCIN 95.00% | 19246-24-3 | 5MG | $497.6 | 2021-12-16 | Buy |
Telomycin Chemical Properties,Uses,Production
Uses
Telomycin is an antibiotic that potently inhibits gram-postive bacteria.
Uses
Telomycin is a complex, high molecular weight depsipeptide discovered in 1958. The structure was not solved until 1968. Telomycin possesses potent and highly selective activity against Gram positive bacteria in vitro and in vivo when given by intramuscular administration. Telomycin is poorly absorbed after oral administration. Despite its structural novelty, telomycin has received little attention.
Uses
Telomycin is a complex, high molecular weight depsipeptide discovered in 1958. The structure was subsequently solved in 1968. Telomycin possesses potent and highly selective activity against Gram positive bacteria in vitro and in vivo when given by intramuscular administration. Telomycin is poorly absorbed after oral administration. Despite its structural novelty, telomycin has received little attention.
Telomycin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
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Telomycin
N-(L-βAsp-L-Ser-)Cyclo(L-Thr*-L-aThr-L-Ala-Gly-L-t3Hyp-3-(1H-indole-3-yl)Dha-β-methyl-L-Trp-4,4-dimethyl-L-aThr-L-c3Hyp-)
18H-Dipyrrolo[2,1-C:2',1'-o][1,4,7,10,13,16,19,22,25]oxaoctaazacyclooctacosine
A-128
Antibiotic 128
L-Proline, L-.beta.-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-trans-3-hydroxy-L-prolyl-erythro-3-hydroxy-L-leucyl-.beta.-methyl-L-tryptophyl-.alpha.,.beta.-didehydro-L-tryptophyl-cis-3-hydroxy-, .beta.1-lactone
Nsc235069
A 128-HYP, A 128-OP
L-Proline, L-β-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-(3S)-3-hydroxy-L-prolyl-α,β-didehydrotryptophyl-β-methyl-L-tryptophyl-(3S)-3-hydroxy-L-leucyl-3-hydroxy-, (11→3)-lactone, (3R)-
19246-24-3
C59H77N13O19