ChemicalBook >> CAS DataBase List >>6,7-dimethoxyphthalide

6,7-dimethoxyphthalide

CAS No.
569-31-3
Chemical Name:
6,7-dimethoxyphthalide
Synonyms
Opianyl;Meconine;NSC 35547;Meconic lactone;6,7-dimethoxyphthalide;Noscapine Impurity 4(Meconine);Meconin (1.0 mg/mL in Chloroform);6,7-dimethoxy-3H-2-benzofuran-1-one;6,7-DiMethoxy-3H-1-isobenzofuranone;6,7-dimethoxy-3H-isobenzofuran-1-one
CBNumber:
CB4883065
Molecular Formula:
C10H10O4
Molecular Weight:
194.184
MDL Number:
MFCD00219354
MOL File:
569-31-3.mol
Last updated:2023-06-08 09:03:06

6,7-dimethoxyphthalide Properties

Melting point 103℃
Boiling point 290.62°C (rough estimate)
Density 1.2534 (rough estimate)
refractive index 1.5430 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
Water Solubility 2.5g/L(25 ºC)
FDA UNII MK5R222CG0

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
HS Code  2932990090
NFPA 704
0
2 0

6,7-dimethoxyphthalide price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9001140 Meconin ≥95% 569-31-3 5mg $61 2024-03-01 Buy
Cayman Chemical 9001140 Meconin ≥95% 569-31-3 10mg $115 2024-03-01 Buy
Cayman Chemical 9001140 Meconin ≥95% 569-31-3 50mg $468 2024-03-01 Buy
Apolloscientific OR928256 6,7-Dimethoxyisobenzofuran-1(3H)-one 98% 569-31-3 1g $220 2021-12-16 Buy
AK Scientific 6419AJ 6,7-Dimethoxyisobenzofuran-1(3H)-one 569-31-3 1g $284 2021-12-16 Buy
Product number Packaging Price Buy
9001140 5mg $61 Buy
9001140 10mg $115 Buy
9001140 50mg $468 Buy
OR928256 1g $220 Buy
6419AJ 1g $284 Buy

6,7-dimethoxyphthalide Chemical Properties,Uses,Production

Synthesis

Compound 7 (91.0 g, 0.5 mol), HCHO solution (81 g, 1.0 mol), HCl (80 g, 0.8 mol) and AcOH (200 g) were heated at 50~60 °C for 24 h to obtain a clear solution, which was then poured into cold water Chemicalbook (1kg). The resulting solid was collected by suction filtration, washed with water (60 g x 3), and dried at 50 °C to give crude cinnamon 8 (95 g) as a tan solid, which was purified by recrystallization from 90% MeOH/H2O (180 g) ) to obtain purified Meconin.

Chemical Properties

White Solid

Uses

A lactone of meconinic acid, extracted from opium. Meconin is a marker for illicit opiate use.

Definition

ChEBI: Meconine is a member of 2-benzofurans.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 3369, 1987 DOI: 10.1016/S0040-4039(00)95515-1

6,7-dimethoxyphthalide Preparation Products And Raw materials

Global( 66)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12468 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
CR Corporation Lomited
fred.wen@crcorporation.cn CHINA 12069 58
Hebei Duling International Trade Co. LTD
+8618032673083 sales05@hbduling.cn China 15745 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58

569-31-3(6,7-dimethoxyphthalide )Related Search:

6,7-dimethoxyphthalide 6,7-Dimethoxy-1(3H)-isobenzofuranone 6,7-Dimethoxyisobenzofuran-1(3H)-one Meconic lactone 6,7-dimethoxy-3H-2-benzofuran-1-one 6,7-dimethoxy-3H-isobenzofuran-1-one NSC 35547 Opianyl Meconine 6,7-DiMethoxy-3H-1-isobenzofuranone Noscapine Impurity 4(Meconine) cyanoformic acid (phenylmethyl) ester 1(3H)-Isobenzofuranone, 6,7-dimethoxy- Meconin (1.0 mg/mL in Chloroform) Inhibitor,Endogenous Metabolite,Meconine,Meconin,inhibit 569-31-3 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals