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Virginiamycin S1

Virginiamycin S1
Virginiamycin S1 structure
CAS No.
23152-29-6
Chemical Name:
Virginiamycin S1
Synonyms
Antibiotic 899;Staphylomycin S;Verginiamycin S1;Virginiamycin S1;Antibiotic 1754Z3B;VirginiaMycin coMplex;Antibiotic 899, Staphylomycin S;StaphyloMycin S, PA 114B2, 899, A1745Z3B, Factor S;N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-N-methyl-L-Phe-4-oxo-L-pipecoloyl-L-phenyl Gly-];N-[(3-Hydroxy-2-pyridyl)carbonyl]cyclo(L-Thr*-D-Abu-L-Pro-N-methyl-L-Phe-4-oxo-L-2-piperidinecarbonyl-L-phenyl Gly-)
CBNumber:
CB4887230
Molecular Formula:
C43H49N7O10
Formula Weight:
823.89
MOL File:
23152-29-6.mol

Virginiamycin S1 Properties

Melting point:
240-242°
alpha 
D20 -28° (c = 1 in ethanol)
storage temp. 
?20°C
solubility 
methanol: soluble5mg/mL
form 
powder
color 
white
FDA UNII
J91D5GN5AT
SAFETY
  • Risk and Safety Statements
WGK Germany  3

Virginiamycin S1 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V4140 Virginiamycin S1 ≥99% (HPLC) 23152-29-6 5mg $384 2021-03-22 Buy
Cayman Chemical 17455 Virginiamycin S1 ≥99% 23152-29-6 25mg $998 2021-03-22 Buy
Cayman Chemical 17455 Virginiamycin S1 ≥99% 23152-29-6 5mg $285 2021-03-22 Buy

Virginiamycin S1 Chemical Properties,Uses,Production

Uses

Virginiamycin complex is defined as a mixture of 75% ostreogrycin A (virginamycin M1) and 25% virginiamycin S1, together with the less abundant S analogues. As the two major components have quite different solubilities, these proportions are not readily achieved or used. BioAustralis has isolated and re-combined the individual components to provide the defined components of virginiamycin complex. The composition of the complex is important as Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

Uses

Virginiamycin S1 is one of a family of depsipeptide antibiotics co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A. 

Contact allergens

Like the other streptogramin, pristinamycin, virginiamycin is made of two subunits, virginiamycin S1 and virginiamycin M1. Dermatitis was quite common in people using the formerly available topical virginiamycin. Occupational dermatitis was observed in the pharmaceutical industry, in breeders, and in a surgeon who used topical virginiamycin on postoperative wounds (personal observation).

Virginiamycin S1 Preparation Products And Raw materials

Raw materials

Preparation Products


Virginiamycin S1 Suppliers

Global( 42)Suppliers
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BOC Sciences
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Shenzhen Polymeri Biochemical Technology Co., Ltd. 400-002-6226
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