ChemicalBook >> CAS DataBase List >>1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
- CAS No.
- 16899-81-3
- Chemical Name:
- 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
- Synonyms
- U 12844A;Isoprenaline impurity A;Norepinephrine Impurity 10;Isoprenaline EP Impurity A;Isoprenaline impurity A CRS;Isoprenaline EP Impurity A HCl;Isoprenaline HCl EP Impurity A;Isoprenaline HCl EP Impurity A HCl;Isoprenaline hydrochloride EP Impurity A;3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE
- CBNumber:
- CB4912824
- Molecular Formula:
- C11H15NO3.ClH
- Molecular Weight:
- 245.704
- MDL Number:
- MFCD00035076
- MOL File:
- 16899-81-3.mol
Last updated:2023-04-23 13:52:06
Melting point | 255-257℃ |
---|---|
FDA UNII | X4JS3SRV5Y |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301+P312+P330 |
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | Y0001577 | Isoprenaline impurity A European Pharmacopoeia (EP) Reference Standard | 16899-81-3 | y0001577 | $220 | 2024-03-01 | Buy |
Sigma-Aldrich | S346322 | Isoprenaline impurity A Aldrich | 16899-81-3 | 50mg | $179 | 2024-03-01 | Buy |
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Chemical Properties,Uses,Production
Uses
1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone is an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia.
Preparation
Obtained by condensation of a-chloro-3,4- dihydroxy-acetophenone with isopropylamine in isopropanol at 65–70°. The amino ketone which separated was treated with concentrated hydrochloric acid (54%), (46%).
Synthesis of 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride from 2-Chloro-3',4'-dihydroxyacetophenone
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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1of4
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-, hydrochloride (1:1)
1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone hydrochloride
Isoprenaline impurity A
U 12844A
[2-(3,4-DIHYDROXYPHENYL)-2-OXOETHYL]-PROPAN-2-YLAZANIUM,CHLORIDE
3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE
Norepinephrine Impurity 10
Isoprenaline EP Impurity A HCl
Isoprenaline EP Impurity A
Isoprenaline impurity A CRS
Isoprenaline HCl EP Impurity A HCl
Isoprenaline hydrochloride EP Impurity A
Isoprenaline Hydrochloride Impurity 1(Isoprenaline Hydrochloride EP Impurity A)
Isoprenaline HCl EP Impurity A
1-(3,4-dihydroxyphenyl)-2-(isopropyl amino) ethan-1-one Hydrochloride
3,4-dihydroxyphenyl isopropylamino-methyl ketone hydrochloride
1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanone hydrochloride (Isoprenaline HCl Impurity)
16899-81-3