Boronic acid, (5-cyano-2-methoxyphenyl)- (9CI)
- CAS No.
- 612833-37-1
- Chemical Name:
- Boronic acid, (5-cyano-2-methoxyphenyl)- (9CI)
- Synonyms
- 5-Cyano-2-Methoxyphenylboronic acid, >95%;Boronic acid, B-(5-cyano-2-methoxyphenyl)-;Boronic acid, (5-cyano-2-methoxyphenyl)- (9CI)
- CBNumber:
- CB51054083
- Molecular Formula:
- C8H8BNO3
- Molecular Weight:
- 176.96
- MDL Number:
- MFCD06801691
- MOL File:
- 612833-37-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Cyano-2-methoxyphenylboronicacid | C982193 | 100mg | $45 |
| 5-Cyano-2-methoxyphenylboronicacid | C982193 | 250mg | $50 |
| 5-Cyano-2-methoxyphenylboronic acid | FC76349 | 100mg | $55 |
| 5-Cyano-2-methoxyphenylboronic acid >95% | 047126 | 5g | $296 |
| 5-Cyano-2-methoxyphenylboronic acid | FC76349 | 2g | $340 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
| HazardClass | IRRITANT |
| HS Code | 2931900090 |
Boronic acid, (5-cyano-2-methoxyphenyl)- (9CI) price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C982193 | 5-Cyano-2-methoxyphenylboronicacid | 612833-37-1 | 100mg | $45 | 2021-12-16 | Buy |
| TRC | C982193 | 5-Cyano-2-methoxyphenylboronicacid | 612833-37-1 | 250mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC76349 | 5-Cyano-2-methoxyphenylboronic acid | 612833-37-1 | 100mg | $55 | 2021-12-16 | Buy |
| Matrix Scientific | 047126 | 5-Cyano-2-methoxyphenylboronic acid >95% | 612833-37-1 | 5g | $296 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC76349 | 5-Cyano-2-methoxyphenylboronic acid | 612833-37-1 | 2g | $340 | 2021-12-16 | Buy |
Boronic acid, (5-cyano-2-methoxyphenyl)- (9CI) Chemical Properties,Uses,Production
Synthesis
5419-55-6
117572-79-9
612833-37-1
The general procedure for the synthesis of 2-methoxy-5-cyanophenylboronic acid from triisopropyl borate and 3-bromo-4-methoxybenzonitrile was as follows: firstly, 3-bromo-4-methoxybenzonitrile (7.7 g, 36 mmol) and triisopropyl borate (14 g, 73 mmol) were dissolved in tetrahydrofuran (150 mL), and then at -78 °C, 2.5 mol/L of n butyl lithium (hexane solution, 22 mL, 55 mmol), and the addition process lasted for 20 min. After the reaction mixture was stirred at -78 °C for 2 h, 7% phosphoric acid (100 mL) was added and the mixture was gradually warmed to room temperature. Subsequently, the reaction mixture was partitioned by adding dichloromethane to the organic layer and extracting the mixture with 5% aqueous sodium hydroxide (200 mL). The aqueous layer was washed with ether and adjusted to pH 2.5 with 85% phosphoric acid and the insoluble material was collected by filtration. The resulting solid was washed with water and dried to give the final 2-methoxy-5-cyanophenylboronic acid (5.1 g, 29 mmol, 79% yield). The product was detected by mass spectrometry (ESI) at m/z 178 (M+H)+; 1H NMR (300 MHz, DMSO-d6) δ 8.03 (s, 2H), 7.86-7.78 (m, 2H), 7.13 (d, J=11.6 Hz, 1H), 3.85 (s, 3H).
References
[1] Patent: US2016/332999, 2016, A1. Location in patent: Paragraph 0649; 0650; 0651
[2] Patent: EP3330266, 2018, A1. Location in patent: Paragraph 0169
Boronic acid, (5-cyano-2-methoxyphenyl)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Boronic acid, (5-cyano-2-methoxyphenyl)- (9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11811 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +8618629664246 | guoyuan@eastchinapharm.com | China | 1615 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| Tianjin Xinghan Biotechnology Co., Ltd | +8618698089028 | 1725517238@qq.com | China | 2479 | 58 |
| Shanghai Scochem Technology Co., Ltd | +86-021-33758897 +86-13701882790 | sales@scochem.com | China | 1977 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 |
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