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Methyl 5-amino-2,4-difluorobenzoate

Methyl 5-amino-2,4-difluorobenzoate Structure
Methyl 5-amino-2,4-difluorobenzoate structure
CAS No.
125568-73-2
Chemical Name:
Methyl 5-amino-2,4-difluorobenzoate
Synonyms
Methyl 5-amino-2,4-difluorobenzoate;Methyl 5-amino-2,4-difluorobenzoate USP/EP/BP;Benzoic acid, 5-amino-2,4-difluoro-, methyl ester;Benzoic acid, 5-amino-2,4-difluoro-, methyl ester (9CI)
CBNumber:
CB51070708
Molecular Formula:
C8H7F2NO2
Molecular Weight:
187.14
MDL Number:
MFCD09396710
MOL File:
125568-73-2.mol
MSDS File:
SDS
Last updated:2026-05-28 01:21:50
Product description Number Pack Size Price
Methyl 5-amino-2,4-difluorobenzoate >98% PC902802 1g $21
Methyl 5-amino-2,4-difluorobenzoate >98% PC902802 5g $36
Methyl 5-amino-2,4-difluorobenzoate >98% PC902802 25g $73
Methyl 5-amino-2,4-difluorobenzoate >98% PC902802 100g $278
Methyl 5-amino-2,4-difluorobenzoate >98% PC902802 500g $1332
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Methyl 5-amino-2,4-difluorobenzoate Properties

Boiling point 284.0±40.0 °C(Predicted)
Density 1.355±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 2.12±0.10(Predicted)
Appearance Off-white to gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2922498590

Methyl 5-amino-2,4-difluorobenzoate price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC902802 Methyl 5-amino-2,4-difluorobenzoate >98% 125568-73-2 1g $21 2026-06-04 Buy
Apolloscientific PC902802 Methyl 5-amino-2,4-difluorobenzoate >98% 125568-73-2 5g $36 2026-06-04 Buy
Apolloscientific PC902802 Methyl 5-amino-2,4-difluorobenzoate >98% 125568-73-2 25g $73 2026-06-04 Buy
Apolloscientific PC902802 Methyl 5-amino-2,4-difluorobenzoate >98% 125568-73-2 100g $278 2026-06-04 Buy
Apolloscientific PC902802 Methyl 5-amino-2,4-difluorobenzoate >98% 125568-73-2 500g $1332 2026-06-04 Buy
Product number Packaging Price Buy
PC902802 1g $21 Buy
PC902802 5g $36 Buy
PC902802 25g $73 Buy
PC902802 100g $278 Buy
PC902802 500g $1332 Buy

Methyl 5-amino-2,4-difluorobenzoate Chemical Properties,Uses,Production

Uses

Methyl 5-amino-2,4-difluorobenzoate is a carboxylic acid ester derivative used in pharmaceutical synthesis and experimental research.

Synthesis

2,4-DIFLUORO-5-NITROBENZOIC ACID METHYL ESTER

125568-71-0

Methyl 5-amino-2,4-difluorobenzoate

125568-73-2

General procedure for the synthesis of methyl 5-amino-2,4-difluorobenzoate from methyl 2,4-difluoro-5-nitrobenzoate: to a solution of methyl 2,4-difluoro-5-nitrobenzoate (12.0 g, 0.06 mol, 1 eq.) in acetic acid (150 mL) and water was added iron powder (12.3 g, 0.22 mol, 4 eq.). The reaction mixture was heated to 40 °C and kept for 1.5 hours. After completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was extracted with ethyl acetate. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated to afford methyl 5-amino-2,4-difluorobenzoate (10.0 g, 96% yield) as a brown solid.1H NMR (400 MHz, DMSO-d6) δppm: 7.27 (dd, J=9.98,7.42 Hz, 1H), 7.14 (t, J=10.99 Hz, 1H), 5.28 (s, 2H), 3.77 (s, 3H).ES-LCMS: m/z 189.0 (M+H).

References

[1] Patent: WO2009/75960, 2009, A1. Location in patent: Page/Page column 22
[2] Patent: WO2009/58919, 2009, A1. Location in patent: Page/Page column 23
[3] Patent: WO2009/58923, 2009, A1. Location in patent: Page/Page column 12
[4] Journal of Organic Chemistry, 1990, vol. 55, # 7, p. 2034 - 2044

Methyl 5-amino-2,4-difluorobenzoate Preparation Products And Raw materials

Raw materials

2,4-DIFLUORO-5-NITROBENZOIC ACID METHYL ESTER 5-AMino-2,4-difluorobenzoic acid, 98% Methanol

Preparation Products

Methyl 5-amino-2,4-difluorobenzoate Suppliers

Global( 95)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14304 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 27945 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Changzhou Ansciep Chemical Co., Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Win-Win chemical CO., Limited 		58
Dideu Industries Group Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from Methyl 5-amino-2,4-difluorobenzoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 5-amino-2,4-difluorobenzoate pictures 2019-12-26 Methyl 5-amino-2,4-difluorobenzoate
125568-73-2
 $1.00 1KG 99% 200kg Career Henan Chemical Co

Methyl 5-amino-2,4-difluorobenzoate Spectrum

Methyl 5-amino-2,4-difluorobenzoate(125568-73-2)1HNMR

125568-73-2(Methyl 5-amino-2,4-difluorobenzoate)Related Search:

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Benzoic acid, 5-amino-2,4-difluoro-, methyl ester (9CI) Methyl 5-amino-2,4-difluorobenzoate Benzoic acid, 5-amino-2,4-difluoro-, methyl ester Methyl 5-amino-2,4-difluorobenzoate USP/EP/BP 125568-73-2 AMINOACID