ChemicalBook >> CAS DataBase List >>1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid structure

CAS No.: 93107-30-3

Chemical Name:: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

Synonyms: 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;14002-6N;7-difluoro-4-oxo-1;Valine Impurity 125;Ciprofloxacin Intermediate;CIPROFLOXACIN CARBOXYLIC ACID;Moxifloxacin Difluoro Acid Impurity;Bexifloxacin hydrochloride intermediate *;1-CYCLOPROPYL-6,7-DIFLUORO-4-OXOQUINOLINE-3-CARBOXYLIC ACID;1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carb...

CBNumber:: CB51092814

Molecular Formula:: C13H9F2NO3

Molecular Weight:: 265.21

MDL Number:: MFCD01646375

MOL File:: 93107-30-3.mol

Last updated:2024-03-20 19:26:33

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1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Properties

Melting point	289°C(lit.)
Boiling point	434.2±45.0 °C(Predicted)
Density	1.630±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO
form	Solid
pka	6.36±0.41(Predicted)
color	Off-White
InChI	InChI=1S/C13H9F2NO3/c14-9-3-7-11(4-10(9)15)16(6-1-2-6)5-8(12(7)17)13(18)19/h3-6H,1-2H2,(H,18,19)
InChIKey	KNEXGVPHPGXAGF-UHFFFAOYSA-N
SMILES	N1(C2CC2)C2=C(C=C(F)C(F)=C2)C(=O)C(C(O)=O)=C1
EWG's Food Scores	2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H361-H412
Precautionary statements	P201-P202-P273-P280-P308+P313-P405-P501
Hazard Codes	Xn
Risk Statements	62-52/53
Safety Statements	22-36/37-61
HS Code	2933.49.7000

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L133051	1-CYCLOPROPYL-6,7-DIFLUORO-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID AldrichCPR	93107-30-3	25MG	$110	2024-03-01	Buy
TCI Chemical	C2779	1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid >98.0%(HPLC)(T)	93107-30-3	1g	$74	2024-03-01	Buy
TCI Chemical	C2779	1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid >98.0%(HPLC)(T)	93107-30-3	5g	$250	2021-12-16	Buy
TRC	C989685	1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid	93107-30-3	1g	$95	2021-12-16	Buy
Biosynth Carbosynth	FC33263	1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid	93107-30-3	5G	$100	2021-12-16	Buy

Product number	Packaging	Price	Buy
L133051	25MG	$110	Buy
C2779	1g	$74	Buy
C2779	5g	$250	Buy
C989685	1g	$95	Buy
FC33263	5G	$100	Buy

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Chemical Properties,Uses,Production

Uses

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid is a metabolite of Moxifloxacin (M745000) and is used in the synthesis of chiral aminopiperidinyl quinolones as potent antibacterial agents against resistant pathogens.

General Description

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid and 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3 -Carboxylic Acid has a similar structure; the difference lies in the number of substituted fluorine atoms. They could be formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Preparation Products And Raw materials

Raw materials

Sodium hydride 2-Chloro-4,5-difluorobenzoic acid Cyclopropylamine Hexane Acetonitrile

Nitrogen Ethanol Acetic anhydride N,N-Dimethylformamide Triethyl orthoformate

Toluene Carbon tetrachloride 1,4-Dioxane Diethyl ether Acetic acid

Methanol Oxalyl chloride Diethyl malonate Magnesium Sulfuric acid

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Preparation Products

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Suppliers

Global( 153)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Enki Biopharmaceuticals (Shanghai) Limited	+86-0086-2157680326 +8613916707528	yusu@enkibiopharma.com	China	47	58
Shaanxi Franta Biotechnology Co., Ltd	+86-13082019107 +86-13082019107	admin@flanderff.com	China	229	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12468	58

Supplier	Advantage
Enki Biopharmaceuticals (Shanghai) Limited	58
Shaanxi Franta Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58

View Lastest Price from 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-03-27	1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid 93107-30-3	US $20.00 / kg	1kg	99%	1000kg	Shaanxi Franta Biotechnology Co., Ltd
	2019-12-31	1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 93107-30-3	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
93107-30-3
US $20.00 / kg
99%
Shaanxi Franta Biotechnology Co., Ltd

1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
93107-30-3
US $7.00 / KG
99%
Career Henan Chemical Co

93107-30-3(1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid)Related Search:

Perfluoro-1-iodohexane METHYL 1-N-CYCLOPROPYL-6,7-DIFLUORO-8-METHYL-5-NITRO-4-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLATE 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester 1-CYCLOPROPYL-6,7-DIFLUORO-8-DIFLUOROMETHOXY-4-OXO-3-QUINOLINE CARBOXYLIC ACID ETHYL 1-CYCLOPROPYL-5,6,7,8-TETRAFLUORO-4(1H)-OXOQUINOLINE-3-CARBOXYLATE

1-CYCLOPROPYL-5-NITRO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid AKOS 1130 5-AMINO-1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-8-METHYL-4-OXO-3-QUINOLINECARBOCYLIC ACID 1-CYCLOPROPYL-5-AMIDO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER

ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydroquinoline-4-oxo-3-carboxyla 1-CYCLOPROPYL-6,7-DIFLUORO-5-METHYL-4-OXO-3-QUINOLINE CARBOXYLIC ACID 1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoq 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

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1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 6,7-DIFLUORO-4-OXO-1-CYCLOPROPYL-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID 1-CYCLOPROPYL-6,7-DIFLUORO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 3-Quinolinecarboxylic acid, 1-cyclopropyl-6,7- difluoro-1,4-dihydro-4-oxo- Ciprofloxacin Intermediate Moxifloxacin Difluoro Acid Impurity 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid > CIPROFLOXACIN CARBOXYLIC ACID 7-difluoro-4-oxo-1 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carb... 1-Cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Bexifloxacin hydrochloride intermediate * CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID Valine Impurity 125 14002-6N 93107-30-3