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4-Iodoaniline

CAS No.
540-37-4
Chemical Name:
4-Iodoaniline
Synonyms
BENZENAMINE, 4-IODO-;P-IODOANILINE;4-iodobenzenamine;4-IodoaniL;4-LODANILINE;4-IODOANILINE;4-iodo-anilin;p-iodo-anilin;Iodine aniline;4-Indo Aniline
CBNumber:
CB5110557
Molecular Formula:
C6H6IN
Molecular Weight:
219.02
MDL Number:
MFCD00007848
MOL File:
540-37-4.mol
MSDS File:
SDS
Last updated:2024-04-25 17:59:01

4-Iodoaniline Properties

Melting point 61-63 °C(lit.)
Boiling point 268.7±23.0 °C(Predicted)
Density 1.8155 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility H2O: slightly soluble
form Crystalline Powder or Needles
pka 3.81(at 25℃)
color Beige to grayish-brown
Water Solubility Slightly soluble in water.Soluble in chloroform, methanol.
Sensitive Light Sensitive
Merck 14,5027
BRN 774101
InChIKey VLVCDUSVTXIWGW-UHFFFAOYSA-N
CAS DataBase Reference 540-37-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 0BMK56397B
NIST Chemistry Reference Benzenamine, 4-iodo-(540-37-4)
EPA Substance Registry System Benzenamine, 4-iodo- (540-37-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36/37/39-36
RIDADR  2811
WGK Germany  3
RTECS  BY3850000
8
Hazard Note  Harmful/Irritant
TSCA  T
HazardClass  6.1(b)
PackingGroup  III
HS Code  29214210
NFPA 704
1
2 1

4-Iodoaniline price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 129364 4-Iodoaniline 98% 540-37-4 25g $59 2024-03-01 Buy
Sigma-Aldrich 129364 4-Iodoaniline 98% 540-37-4 100g $73.6 2024-03-01 Buy
TCI Chemical I0048 4-Iodoaniline 540-37-4 25G $68 2024-03-01 Buy
TCI Chemical I0048 4-Iodoaniline 540-37-4 250G $215 2022-04-27 Buy
Alfa Aesar B21936 4-Iodoaniline, 98% 540-37-4 50g $73.9 2024-03-01 Buy
Product number Packaging Price Buy
129364 25g $59 Buy
129364 100g $73.6 Buy
I0048 25G $68 Buy
I0048 250G $215 Buy
B21936 50g $73.9 Buy

4-Iodoaniline Chemical Properties,Uses,Production

Chemical Properties

beige to greyish-brown crystalline powder. soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

suzuki reaction

Uses

4-dehydroanilinium ion, a stable distonic isomer of ionized aniline, by collision-activated dissociation of protonated 4-iodoaniline. Palladium-catalyzed carbonylation of 4-iodoaniline gave the corresponding four- armed star polybenzamides. 4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of dyes and drugs. 4-Iodoaniline was used to prepare phenyl functionalized graphene oxide (I-Ph-GO).

Uses

4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of pesticides, dyes and drugs. 4-Iodoaniline was shown to be a more potent nephrotoxica nt in vitro than other anilines.

Preparation

4-Iodoaniline is obtained by the reaction of aniline and iodine in the presence of sodium bicarbonate. Add aniline and sodium bicarbonate to water and slowly add crushed iodine in stages with vigorous stirring. If the reaction solution is yellow, add a little sodium bisulfite to make it discolor, then filter and get the crude product. Then the product is recrystallized by ethanol to obtain 4-Iodoaniline.

General Description

4-Iodoaniline is the most potent methaemoglobin former.

Purification Methods

Crystallise it from pet ether (b 60-80o) by refluxing, then cool it in an ice-salt bath freezing mixture. Dry it in air. Alternatively, crystallise it from EtOH and dry it in vacuo for 6hours at 40o [Edidin et al. J Am Chem Soc 109 3945 1987]. The N-acetyl derivative has m 184o (from MeOH). [Beilstein 12 IV 1544.]

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Henan Fengda Chemical Co., Ltd
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View Lastest Price from 4-Iodoaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Iodoaniline pictures 2024-04-25 4-Iodoaniline
540-37-4
US $100.00-30.00 / kg 1kg 99.93% 1000kg per week Ouhuang Engineering Materials (Hubei) Co., Ltd
4-Iodoaniline pictures 2024-04-08 4-Iodoaniline
540-37-4
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
4-Iodoaniline pictures 2023-12-24 4-Iodoaniline
540-37-4
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • 4-Iodoaniline pictures
  • 4-Iodoaniline
    540-37-4
  • US $100.00-30.00 / kg
  • 99.93%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • 4-Iodoaniline pictures
  • 4-Iodoaniline
    540-37-4
  • US $0.00-0.00 / Kg
  • 99.9%
  • airuikechemical co., ltd.
  • 4-Iodoaniline pictures
  • 4-Iodoaniline
    540-37-4
  • US $100.00-1.00 / KG
  • 99%
  • Henan Fengda Chemical Co., Ltd
1-amino-4-iodobenzene 4-IODOANILINE 4-LODANILINE 4-iodo-anilin 4-iodo-benzenamin 4-iodo-Benzenamine 1-Iodo-4-aminobenzene p-Aminoiodobenzene 4-Aminophenyl iodide 4-Iodoaniline,99% 4-IodobenzeneaMine 4-Iodoaniline, 99% 25GR The iodine aniline Iodine aniline 4-Iodoaniline≥ 98% (GC) 4-Iodo-phenylamine Aniline, 4-iodo- Aniline, p-iodo- Benzenamine,4-Iodoaniline p-Aminophenyl iodide p-aminophenyliodide p-iodo-anilin 4-Indo Aniline IODOANILINE, 4- 4-Iodoaniline,~98% 4-IodoaniL 4-Iodoaniline, 98%, for synthesis 4-Iodoaniline> 4 - iodine aniline 4-Iodoaniline ISO 9001:2015 REACH BENZENAMINE, 4-IODO- P-IODOANILINE 4-iodobenzenamine p-lodoaniline RSYY(Apremilast)-8 4 Iodoaniline (P-Iodoaniline,4-Iodobenzenamine) 540-37-4 IC6H4NH2 IC6H6N C2 to C6 Building Blocks Amines AMINE Organic Building Blocks Nitrogen Compounds Building Blocks C6 Chemical Synthesis Nitrogen Compounds Organic Building Blocks Pharmaceutical Intermediates Anilines, Aromatic Amines and Nitro Compounds Amines API intermediates Anilines, Amides & Amines Iodine Compounds C2 to C6 Nitrogen Compounds