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2H-1,4-BENZOXAZIN-3(4H)-ONE

2H-1,4-BENZOXAZIN-3(4H)-ONE structure

CAS No.: 5466-88-6

Chemical Name:: 2H-1,4-BENZOXAZIN-3(4H)-ONE

Synonyms: AURORA KA-5421;4-AZA-3-CHROMANONE;OTAVA-BB BB7020041238;1,4-Benzoxazine-3-one;BENZO[B]MORPHOLIN-3-ONE;4H-1,4-benzoxazin-3-one;2H-1,4-Benzoxazin-3-one;4H-BENZO[1,4]OXAZIN-3-ONE;3-OXO-4H-BENZO[1,4]OXAZINE;2H-1,4-BENZOXAZIN-3(4H)-ONE

CBNumber:: CB5111761

Molecular Formula:: C8H7NO2

Molecular Weight:: 149.15

MDL Number:: MFCD00158536

MOL File:: 5466-88-6.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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2H-1,4-BENZOXAZIN-3(4H)-ONE Properties

Melting point	173-175 °C(lit.)
Boiling point	337.7±31.0 °C(Predicted)
Density	1.244±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	methanol: soluble25mg/mL, clear, colorless
form	Flakes or Powder
pka	12.89±0.20(Predicted)
color	White to yellow to tan
λmax	286nm(EtOH)(lit.)
CAS DataBase Reference	5466-88-6(CAS DataBase Reference)
FDA UNII	Q0QAF5G662

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39

WGK Germany

RTECS

DM3270000

HazardClass

IRRITANT

HS Code

29349990

NFPA 704

	1
2		0

2H-1,4-BENZOXAZIN-3(4H)-ONE price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	383503	2H-1,4-Benzoxazin-3(4H)-one 99%	5466-88-6	25g	$25.8	2024-03-01	Buy
Sigma-Aldrich	383503	2H-1,4-Benzoxazin-3(4H)-one 99%	5466-88-6	5g	$48	2023-06-20	Buy
TCI Chemical	B4553	2H-1,4-Benzoxazin-3(4H)-one >98.0%(GC)	5466-88-6	5g	$23	2024-03-01	Buy
TCI Chemical	B4553	2H-1,4-Benzoxazin-3(4H)-one >98.0%(GC)	5466-88-6	25g	$69	2024-03-01	Buy
Alfa Aesar	H27622	2H-1,4-Benzoxazin-3(4H)-one, 99%	5466-88-6	5g	$25.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
383503	25g	$25.8	Buy
383503	5g	$48	Buy
B4553	5g	$23	Buy
B4553	25g	$69	Buy
H27622	5g	$25.65	Buy

2H-1,4-BENZOXAZIN-3(4H)-ONE Chemical Properties,Uses,Production

Chemical Properties

white to almost white crystalline powder

Uses

2H-1,4-Benzoxazin-3-one is used to prepare benzoxazinone/benzothiazinone analogs of fluconazole with antifungal and anti-Candida activities. It is used to synthesize 1,?4-?benzoxazine derivatives with vasorelaxant activities.

Synthesis Reference(s)

Synthesis, p. 851, 1984 DOI: 10.1055/s-1984-30993

General Description

2H-1,4-Benzoxazin-3(4H)-one, a benzoxazine derivative, is a heterocyclic building block for various natural and synthetic organic compounds. It has been reported as an intermediate during the biogenesis of cyclic hydoxamic acids in maize. Its standard molar enthalpy of formation and tautomerization energy of its tautomers has been evaluated by calorimetric and computational methods. It has been synthesized by reacting o-aminophenol with chloroacetyl chloride in the presence of butanone and aqueous NaHCO₃.

2H-1,4-BENZOXAZIN-3(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-6-SULFONYL CHLORIDE 2 3-DIHYDRO-3-OXO-4H-1 4-BENZOXAZINE-4-& Benzomorpholine 6-BROMO-2H-1,4-BENZOXAZIN-3(4H)-ONE 6-(3-phenylprop-2-enoyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one

ETHYL 2-(2,3-DIHYDRO-3-OXOBENZO[B][1,4]OXAZIN-4-YL)ACETATE

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2H-1,4-BENZOXAZIN-3(4H)-ONE Suppliers

Global( 199)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12477	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Accela ChemBio Inc.	58
Changzhou Ditong Chemical Co.,Ltd	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58

View Lastest Price from 2H-1,4-BENZOXAZIN-3(4H)-ONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	2H-1,4-BENZOXAZIN-3(4H)-ONE 5466-88-6	US $1.00 / KG	1KG	98%	1kg,5kg,100kg	Career Henan Chemical Co

2H-1,4-BENZOXAZIN-3(4H)-ONE
5466-88-6
US $1.00 / KG
98%
Career Henan Chemical Co

2H-1,4-BENZOXAZIN-3(4H)-ONE Spectrum

2H-1,4-BENZOXAZIN-3(4H)-ONE(5466-88-6)FT-IR 2H-1,4-BENZOXAZIN-3(4H)-ONE(5466-88-6)IR 2H-1,4-BENZOXAZIN-3(4H)-ONE(5466-88-6)Raman

5466-88-6(2H-1,4-BENZOXAZIN-3(4H)-ONE)Related Search:

Azasetron hydrochloride 7-NITRO-2H-1,4-BENZOXAZIN-3(4H)-ONE 2H-1,4-BENZOXAZIN-3(4H)-ONE 7-FLUORO-2H-1,4-BENZOXAZIN-3(4H)-ONE Lensiprazine

7-METHOXY-1,3-BENZOXAZINE-2,4-DIONE 5-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE 6-NITRO-2H-1,4-BENZOXAZIN-3(4H)-ONE 4-METHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE 4-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE

6-CHLORO-2H-1,4-BENZOXAZIN-3(4H)-ONE ETHYL 2-(2,3-DIHYDRO-3-OXOBENZO[B][1,4]OXAZIN-4-YL)ACETATE 5-Nitro-2H-1,4-benzoxazin-3(4H)-one 8-Amino-2,4-dimethyl-2H-1,4-benzoxazin-3(4H)-one 8-Amino-2-methyl-2H-1,4-benzoxazin-3(4H)-one

8-Amino-2H-1,4-benzoxazin-3(4H)-one ETHYL 2-(6-CHLORO-2,3-DIHYDRO-3-OXOBENZO[B][1,4]OXAZIN-4-YL)ACETATE BUTTPARK 5\07-33

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4H-1,4-benzoxazin-3-one 2H-1,4-Benzoxazin-3(4H)-one 4H-BENZO[1,4]OXAZIN-3-ONE 4-AZA-3-CHROMANONE 2H-1,4-BENZOXAZIN-3(4H)-ONE 2H-1,4-BENZOXAZINE-3(4H)-ONE 2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE OTAVA-BB BB7020041238 BENZO[B]MORPHOLIN-3-ONE AURORA KA-5421 2H-1,4-Benzooxazin-3(4H)-one 3-OXO-4H-BENZO[1,4]OXAZINE 2H-1,4-Benzoxazin-3(4H)-one, (4-Aza-3-chromanone) 2,4-Dihydro-3H-1,4-benzoxazine-3-one 3,4-Dihydro-2H-1,4-benzoxazine-3-one 2H-1,4-Benzoxazin-3(4H)-one,99% 2H-1,4-BENZOXAZIN-3(4H)-ONE 99% 3,4-Dihydro-2H-1,4-benzoxazin-3-one 3,4-dihydro-2H-1,4-benzoxazin-3(4H)-one 2H-1,4-Benzoxazin-3(4H)-one (8CI)(9CI) 2H-1,4-Benzoxazin-3-one 1,4-Benzoxazine-3-one 2H-1,4-Benzoxazin-3(4H)-one > 5466-88-6 2H-1,4-BENZOXAZIN-3(4H)-ONE JRH-03201, 2H-Benzo[b][1,4]oxazin-3(4H)-one, 97% 2H-1,4-Benzoxazin-3(4H)-one (6CI, 7CI, 8CI, 9CI, ACI) 2H-1,4- 6-Benzoxazin-3(4H)-one 5466-88-6 Heterocyclic Building Blocks Building Blocks Benzoxazines pharmacetical API intermediates Miscellaneous Benzoxazines Building Blocks Heterocyclic Building Blocks