ChemicalBook >> CAS DataBase List >>N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
- CAS No.
- 7365-44-8
- Chemical Name:
- N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
- Synonyms
- TES;N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID;Tes Buffer;TES,2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid, TES free acid;TESS;C05353;TESS-2;Tris TES;8-Fluoro-1;OmniPur TES
- CBNumber:
- CB5114267
- Molecular Formula:
- C6H15NO6S
- Molecular Weight:
- 229.25
- MDL Number:
- MFCD00007532
- MOL File:
- 7365-44-8.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Product description | Number | Pack Size | Price |
| OmniPur® TES TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2. | 5.05147 | 100G | $192 |
| OmniPur® TES TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2. | 5.05147 | 1KG | $1060 |
| N-[Tris(hydroxymethyl)-methyl]-2-aminoethanesulfonic acid Buffer substance TES | 1.10695 | 250 g | $440 |
| N-[Tris(hydroxymethyl)-methyl]-2-aminoethanesulfonic acid Buffer substance TES | 1.10695 | 10 kg | $9440 |
| TES BioUltra, ≥99.5% (calc. based on dry substance, T) | 93359 | 25g | $246 |
| More product size | |||
| Melting point | ~225 °C (dec.) |
|---|---|
| Density | 1.260 (estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Crystalline Powder |
| color | White |
| PH | 3.5-5.0 (25℃, 1M in H2O) |
| pka | 7.5(at 25℃) |
| PH Range | 6.8 - 8.2 |
| Odor | Odorless |
| Water Solubility | SOLUBLE |
| λmax |
λ: 260 nm Amax: 0.055 λ: 280 nm Amax: 0.045 |
| Merck | 14,9176 |
| BRN | 1957061 |
| InChIKey | JOCBASBOOFNAJA-UHFFFAOYSA-N |
| CAS DataBase Reference | 7365-44-8(CAS DataBase Reference) |
| FDA UNII | L173DK6289 |
| EPA Substance Registry System | Ethanesulfonic acid, 2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (7365-44-8) |
| Absorption |
≤0.045 at 280 in H2O at 1M ≤0.055 at 260 in H2O at 1M |
| UNSPSC Code | 12161703 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 1 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29221980 | |||||||||
| NFPA 704 |
|
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 5.05147 | OmniPur® TES TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2. | 7365-44-8 | 100G | $192 | 2025-07-31 | Buy |
| Sigma-Aldrich | 5.05147 | OmniPur® TES TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2. | 7365-44-8 | 1KG | $1060 | 2025-07-31 | Buy |
| Sigma-Aldrich | 1.10695 | N-[Tris(hydroxymethyl)-methyl]-2-aminoethanesulfonic acid Buffer substance TES | 7365-44-8 | 250 g | $440 | 2025-07-31 | Buy |
| Sigma-Aldrich | 1.10695 | N-[Tris(hydroxymethyl)-methyl]-2-aminoethanesulfonic acid Buffer substance TES | 7365-44-8 | 10 kg | $9440 | 2025-07-31 | Buy |
| Sigma-Aldrich | 93359 | TES BioUltra, ≥99.5% (calc. based on dry substance, T) | 7365-44-8 | 25g | $246 | 2023-06-20 | Buy |
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Chemical Properties,Uses,Production
Chemical Properties
White/clear crystalline powder
Uses
A structural analog to Tris buffer.
Uses
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid (TES) probably exists in solution as a zwitterion. Because the pKa is 7.4 (physiological pH) this buffer has considerable potential for a variety of biological applications. A buffer using TES free acid can be prepared by titrating the free acid (sc-206102) with sodium hydroxide to the desired pH, using about a half-equivalent of NaOH. Alternatively, solutions of equimolar TES free acid and TES sodium (sc-264384) can be mixed to attain a buffer of the desired pH. It has been shown to be toxic in vitro, but this toxicity may be due to its ability to form metal chelate complexes that are toxic for cells. TES is a commonly used biological buffering agent.
Definition
ChEBI: N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid is a Good's buffer substance, pKa = 7.5 at 20 ℃. It is a member of ethanolamines, an amino sulfonic acid and a TES. It is functionally related to a taurine. It is a tautomer of a N-tris(hydroxymethyl)methyl-2-ammonioethanesulfonate.
Purification Methods
Crystallise the acid from hot EtOH containing a little water.
Synthesis of N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid from 1-Bromo-2-chloroethane and Tris(hydroxymethyl)aminomethane
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 470)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Magic Biotechnology Co., Ltd | +undefined13921770081 | SVP01@magicbiotech.cn | China | 92 | 58 |
| Suzhou Genemill Biotechnology Co.,Ltd | +8615862502491 | aimeegao@genemill.com | China | 39 | 58 |
| Sichuan Zhuoyu Yantang Technology Co., Ltd. | +8613288715578 | sales@sichuanzyyt.com | China | 12217 | 58 |
| Hubei Xindesheng Material Technology Co., Ltd. | +8618971041571 | vickyzhao@whdschem.com | China | 174 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 861 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13502 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21615 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
Related articles
- Uses and Properties of TES buffer
- TES buffer is a zwitterionic biological buffer often used as a buffering agent in biological and biochemical research.
- Aug 1，2022
View Lastest Price from N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-17 | TES
7365-44-8
|
US $5.00 / kg | 1kg | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
![2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid/TES pictures](/ProductImageEN/2021-06/Small/dabdcf8c-f068-413a-9d4d-ed44ae4be03c.jpg) |
2025-11-17 | 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid/TES
7365-44-8
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%-101% | 500KGS | WUHAN FORTUNA CHEMICAL CO., LTD | |
![2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid pictures](/ProductImageEN/2023-11/Small/224fb58a-3de0-4762-9b78-0a4736f3752b.jpg) |
2025-08-08 | 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
7365-44-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Sichuan Zhuoyu Yantang Technology Co., Ltd. |
-
- TES
7365-44-8
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid/TES
7365-44-8
- US $0.00-0.00 / Kg/Drum
- 99%-101%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
7365-44-8
- US $0.00 / KG
- 99%
- Sichuan Zhuoyu Yantang Technology Co., Ltd.
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EZNA MICROELUTE GEL EXTRACTION KIT
Tes(N-Tris[Hydroxymethyl]Methyl-2-AminoethanesulfonicAcid)Buffer
