ChemicalBook >> CAS DataBase List >>N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
- CAS No.
- 7365-44-8
- Chemical Name:
- N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
- Synonyms
- TES;N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID;Tes Buffer;TES,2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid, TES free acid;C05353;Tris TES;8-Fluoro-1;OmniPur TES;TES free acid;3-cd]indol-6-one
- CBNumber:
- CB5114267
- Molecular Formula:
- C6H15NO6S
- Molecular Weight:
- 229.25
- MDL Number:
- MFCD00007532
- MOL File:
- 7365-44-8.mol
- MSDS File:
- SDS
Last updated:2024-03-28 13:39:29
| Melting point | ~225 °C (dec.) |
|---|---|
| Density | 1.260 (estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Crystalline Powder |
| color | White |
| Odor | Odorless |
| PH Range | 6.8 - 8.2 |
| PH | 3.5-5.0 (25℃, 1M in H2O) |
| pka | 7.5(at 25℃) |
| Water Solubility | SOLUBLE |
| λmax |
λ: 260 nm Amax: 0.055 λ: 280 nm Amax: 0.045 |
| Merck | 14,9176 |
| BRN | 1957061 |
| InChIKey | JOCBASBOOFNAJA-UHFFFAOYSA-N |
| CAS DataBase Reference | 7365-44-8(CAS DataBase Reference) |
| FDA UNII | L173DK6289 |
| EPA Substance Registry System | Ethanesulfonic acid, 2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (7365-44-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 1 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29221980 | |||||||||
| NFPA 704 |
|
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 5.05147 | OmniPur® TES TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2. | 7365-44-8 | 100G | $176 | 2024-03-01 | Buy |
| Sigma-Aldrich | 5.05147 | OmniPur® TES TES, CAS 7365-44-8 , is a Zwitterionic buffer that is useful in the pH range of 6.8-8.2. | 7365-44-8 | 1KG | $985 | 2024-03-01 | Buy |
| Sigma-Aldrich | 93359 | TES BioUltra, ≥99.5% (calc. based on dry substance, T) | 7365-44-8 | 25g | $246 | 2023-06-20 | Buy |
| Sigma-Aldrich | 93359 | TES BioUltra, ≥99.5% (calc. based on dry substance, T) | 7365-44-8 | 100g | $589 | 2023-06-20 | Buy |
| TCI Chemical | T0683 | N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid [Good's buffer component for biological research] >98.0%(T) | 7365-44-8 | 25g | $107 | 2024-03-01 | Buy |
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Chemical Properties,Uses,Production
Chemical Properties
White/clear crystalline powder
Uses
A structural analog to Tris buffer.
Uses
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid (TES) probably exists in solution as a zwitterion. Because the pKa is 7.4 (physiological pH) this buffer has considerable potential for a variety of biological applications. A buffer using TES free acid can be prepared by titrating the free acid (sc-206102) with sodium hydroxide to the desired pH, using about a half-equivalent of NaOH. Alternatively, solutions of equimolar TES free acid and TES sodium (sc-264384) can be mixed to attain a buffer of the desired pH. It has been shown to be toxic in vitro, but this toxicity may be due to its ability to form metal chelate complexes that are toxic for cells. TES is a commonly used biological buffering agent.
Definition
ChEBI: N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid is a Good's buffer substance, pKa = 7.5 at 20 ℃. It is a member of ethanolamines, an amino sulfonic acid and a TES. It is functionally related to a taurine. It is a tautomer of a N-tris(hydroxymethyl)methyl-2-ammonioethanesulfonate.
Purification Methods
Crystallise the acid from hot EtOH containing a little water.
Synthesis of N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid from 1-Bromo-2-chloroethane and Tris(hydroxymethyl)aminomethane
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 368)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| XuZhou Magic Biotechnology Co., Ltd. | +undefined13921770081 | SVP01@magicbiotech.cn | China | 92 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hubei Xindesheng Material Technology Co., Ltd. | +8618971041571 | vickyzhao@whdschem.com | China | 174 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 951 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
Related articles
- Uses and Properties of TES buffer
- TES buffer is a zwitterionic biological buffer often used as a buffering agent in biological and biochemical research.
- Aug 1，2022
View Lastest Price from N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | TES
7365-44-8
|
US $5.00 / kg | 1kg | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
![2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid pictures](/ProductImageEN/2024-03/Small/eb8b7b21-90e9-4b51-888f-14f98e5d48d1.jpg) |
2024-04-22 | 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
7365-44-8
|
US $100.00 / kg | 1kg | 99% | 1000 | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-02-20 | TES
7365-44-8
|
US $0.00 / kg | 1kg | 99.5% | 1000tons | Suzhou Genemill Biotechnology Co.,Ltd |
-
- TES
7365-44-8
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
7365-44-8
- US $100.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- TES
7365-44-8
- US $0.00 / kg
- 99.5%
- Suzhou Genemill Biotechnology Co.,Ltd
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N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID
TES