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ChemicalBook >> CAS DataBase List >>(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Structure
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid structure
CAS No.
5130-29-0
Chemical Name:
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
Synonyms
Cholic Acid Impurity 9;12-Ketodeoxycholic acid;5β-CHOLANIC ACID-3α-OL-12-ONE;5β-CHOLANIC acid-3α-OL-12-ONE;3-ALPHA-HYDROXY-12-OXO-5-BETA-CHOLANOICACID;Cholan-24-oic acid, 3-hydroxy-12-oxo-, (3α,5β)-;Cholic Acid IMpurity (3-alpha-Hydroxy-12-Oxo-5-beta-Cholanoic Acid);(4R)-4-((3R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;(R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
CBNumber:
CB51235330
Molecular Formula:
C24H38O4
Molecular Weight:
390.56
MDL Number:
MFCD00200664
MOL File:
5130-29-0.mol
MSDS File:
SDS
Last updated:2023-06-08 09:03:01
Request For Quotation

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Properties

Melting point 165-167 °C
Boiling point 545.9±35.0 °C(Predicted)
Density 1.124±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
form A solid
pka 4.74±0.10(Predicted)
FDA UNII 57668172Z5

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
NFPA 704
0
2 0

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00913 BAA485 (12-Ketodeoxycholic acid) ≥95% (HPLC) 5130-29-0 25MG $213 2023-06-20 Buy
Cayman Chemical 29547 12-keto Lithocholic Acid 5130-29-0 5mg $78 2024-03-01 Buy
Cayman Chemical 29547 12-keto Lithocholic Acid 5130-29-0 50mg $388 2024-03-01 Buy
Cayman Chemical 29547 12-keto Lithocholic Acid 5130-29-0 10mg $124 2024-03-01 Buy
Cayman Chemical 29547 12-keto Lithocholic Acid 5130-29-0 25mg $214 2024-03-01 Buy
Product number Packaging Price Buy
SMB00913 25MG $213 Buy
29547 5mg $78 Buy
29547 50mg $388 Buy
29547 10mg $124 Buy
29547 25mg $214 Buy

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Chemical Properties,Uses,Production

Description

12-keto Lithocholic acid is a metabolite of the secondary bile acid deoxycholic acid (DCA; Item Nos. 20756 | 18231). Fecal levels of 12-keto lithocholic acid are elevated in rats fed a diet supplemented with cholic acid or DCA compared with rats fed a control diet or a diet supplemented with cholesterol , hyodeoxycholic acid (HDCA; ), or lithocholic acid (LCA; ). 12-keto Lithocholic acid activates the human pregnane X receptor (PXR; EC50 = 31.3 μM in a cell-based transactivation assay). 12-keto Lithocholic acid levels are increased in duodenal bile from patients with type 2 diabetes.

Definition

ChEBI: 12-ketolithocholic acid is a bile acid.

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid Suppliers

Global( 30)Suppliers
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Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Zhengzhou Huiju Chemical Co., Ltd. 0371-55900031 18137872243 2853979815@qq.com China 10018 55
Beijing YiboYuntian Technology Co., Ltd. 13811826434 lichen13811826434@126.com China 525 58
Shanghai Standard Technology Co.,Ltd. 021-57127007-6622 15618937986 zhaok@nature-standard.com China 3920 58
Aikon International Limited 025-66113011 18112977050 sales01@aikonchem.com China 16028 58
Shenzhen Botel Biotechnology Co. Ltd. 0755-22202135 13316968096 1979313431@qq.com China 7516 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49323 58
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
ChemStrong Scientific Co.,Ltd 56
Zhengzhou Huiju Chemical Co., Ltd. 55
Beijing YiboYuntian Technology Co., Ltd. 58
Shanghai Standard Technology Co.,Ltd. 58
Aikon International Limited 58
Shenzhen Botel Biotechnology Co. Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58

View Lastest Price from (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
12-Ketodeoxycholic acid pictures 2022-10-11 12-Ketodeoxycholic acid
5130-29-0
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

5130-29-0((4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid)Related Search:

Butyrylcholinesterase Obeticholic Acid
(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid 12-Ketodeoxycholic acid 3-ALPHA-HYDROXY-12-OXO-5-BETA-CHOLANOICACID Cholic Acid IMpurity (3-alpha-Hydroxy-12-Oxo-5-beta-Cholanoic Acid) (4R)-4-((3R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid Cholic Acid Impurity 9 5β-CHOLANIC acid-3α-OL-12-ONE (R)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-12-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid acid,chronic,12Ketodeoxycholic acid,kidney,12 Ketodeoxycholic acid,Inhibitor,injury,NAFLD,Aristolochic,nephropathy,inhibit,Endogenous Metabolite,AAN,disease,12-Ketodeoxycholic acid Cholan-24-oic acid, 3-hydroxy-12-oxo-, (3α,5β)- 5β-CHOLANIC ACID-3α-OL-12-ONE 5130-29-0