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1,2,3,4-TETRAHYDROISOQUINOLINE

Description Reference
1,2,3,4-TETRAHYDROISOQUINOLINE
1,2,3,4-TETRAHYDROISOQUINOLINE structure
CAS No.
91-21-4
Chemical Name:
1,2,3,4-TETRAHYDROISOQUINOLINE
Synonyms
AKOS BB-9293;LABOTEST-BB LTBB000776;Tetrahydroisoquinoline;3,4-Dihydro-1H-isoquinoline.;1,2,3,4-Tetrahydroisochinoline;1,2,3,4-tetrahydro-isoquinolin;1,2,3,4-TETRAHYDROISOQUINOLINE;1,2,3,4-Tetrahydro-2-isoquinoline;1,2,3,4-Tetrahydroisoquinoline ,97%;1,2,3,4-Tetrahydro-#niso-quinoline
CBNumber:
CB5126507
Molecular Formula:
C9H11N
Formula Weight:
133.19
MOL File:
91-21-4.mol

1,2,3,4-TETRAHYDROISOQUINOLINE Properties

Melting point:
−30 °C(lit.)
Boiling point:
232-233 °C(lit.)
Density 
1.064 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.568(lit.)
Flash point:
210 °F
storage temp. 
Store below +30°C.
solubility 
20g/l
form 
Liquid
color 
Clear yellow to brown
Water Solubility 
Soluble in water at 20°C 20g/L.
BRN 
116156
InChIKey
UWYZHKAOTLEWKK-UHFFFAOYSA-N
CAS DataBase Reference
91-21-4(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  NX4900000
Hazard Note  Irritant
TSCA  Yes
HS Code  29334900
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

1,2,3,4-TETRAHYDROISOQUINOLINE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T13005 1,2,3,4-Tetrahydroisoquinoline 95% 91-21-4 25g $40.1 2018-11-20 Buy
Sigma-Aldrich T13005 1,2,3,4-Tetrahydroisoquinoline 95% 91-21-4 100g $118 2018-11-20 Buy
TCI Chemical T1676 1,2,3,4-Tetrahydroisoquinoline >95.0%(GC) 91-21-4 25g $36 2018-11-22 Buy
TCI Chemical T1676 1,2,3,4-Tetrahydroisoquinoline >95.0%(GC) 91-21-4 100g $97 2018-11-22 Buy
Alfa Aesar L08143 1,2,3,4-Tetrahydroisoquinoline, 97% 91-21-4 100g $105 2018-11-13 Buy

1,2,3,4-TETRAHYDROISOQUINOLINE Chemical Properties,Uses,Production

Description

1, 2, 3, 4-TETRAHYDROISOQUINOLINE belongs to tetrahydroisoquinoline compound, which is encountered in a number of drugs, tubocurarine, one of the quaternary ammonium muscle relaxants1-3. It is used as a reagent in the preparation of4-(1, 2, 4-oxadiazol-5-yl) piperidine-1-carboxamides as antiproliferative tubulin inhibitors1. It can be used for the synthesis of 1, 2, 3, 4-tetrahydroisoquinoline-3-carboxylic acid (Tic), which has strong applications in peptides and peptidomimetics design and discovery2. 1, 2, 3, 4-tetrahydroisoquinoline has been made into some derivatives with potential for prevention of parkinsonism4, cancer treatment5 and acting as Anticonvulsant Agents6.

Reference

  1. https://www.alfa.com/en/catalog/L08143/
  2. https://www.ncbi.nlm.nih.gov/pubmed/21235510
  3. https://en.wikipedia.org/wiki/Tetrahydroisoquinoline
  4. Okuda, K, Y. Kotake, and S. Ohta. "Parkinsonism-preventing activity of 1-methyl-1, 2, 3, 4-tetrahydroisoquinoline derivatives in C57BL mouse in vivo. Biological & Pharmaceutical Bulletin 29.7(2006):1401-1403.
  5. Luca, Laura De, et al. "3D Pharmacophore Models for 1, 2, 3, 4‐Tetrahydroisoquinoline Derivatives Acting as Anticonvulsant Agents." Archiv Der Pharmazie 339.7(2006):388-400.
  6. Hatano, H, et al. "Tumor-specific cytotoxic activity of 1, 2, 3, 4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines."Anticancer Research 29.8(2009):3079-3086.

Chemical Properties

clear yellow to brown liquid

1,2,3,4-TETRAHYDROISOQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products


1,2,3,4-TETRAHYDROISOQUINOLINE Suppliers

Global( 191)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12234 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
Kono Chem Co., Ltd
+86-132 8924 6953
info@konochemical.com CHINA 2164 58
Shanghai Co-magnate Industrial Co., Ltd. 021-62165619 13917231399
021-62165619 wangq@co-magnate.com China 128 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40395 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30291 84

View Lastest Price from 1,2,3,4-TETRAHYDROISOQUINOLINE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 1,2,3,4-TETRAHYDROISOQUINOLINE
91-21-4
US $8.00 / kg 1kg 99% 10MT career henan chemical co

1,2,3,4-TETRAHYDROISOQUINOLINE Spectrum


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