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PL017

PL017 structure

CAS No.: 83397-56-2

Chemical Name:: PL017

Synonyms: PL017;TYR-PRO-(NME)PHE-DPRO-NH2;morphiceptin, N-Me-Phe(3)-;[NMPhe3,D-Pro4]morphiceptin;H-TYR-PRO-N-ME-PHE-D-PRO-NH2;[N-ME-PHE3, D-PRO4]-MORPHICEPTIN;L-Tyr-L-Pro-N-Methyl-L-Phe-D-Pro-NH2;[(NME)PHE3, DPRO4] MORPHICEPTIN, BOVINE;[NMePhe3, DPro4] b-Casomorphin: 1-4, amide, bovine;{N-METHYL-PHE3,D-PRO4}-BETA-CASOMORPHIN FRAGMENT 1-

CBNumber:: CB5131318

Molecular Formula:: C29H37N5O5

Molecular Weight:: 535.63

MDL Number:: MFCD00135717

MOL File:: 83397-56-2.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:14

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PL017 Properties

Boiling point	878.5±65.0 °C(Predicted)
Density	1.313±0.06 g/cm3(Predicted)
storage temp.	−20°C
form	Powder
pka	9.86±0.15(Predicted)
Water Solubility	Soluble to 1 mg/ml in water

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

PL017 price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	256279	PL 017	83397-56-2	1mg	$296	2021-12-16	Buy
American Custom Chemicals Corporation	BRS0000669	PL017 95.00%	83397-56-2	5MG	$755.95	2021-12-16	Buy
ApexBio Technology	B5249	PL017	83397-56-2	1mg	$108	2021-12-16	Buy

Product number	Packaging	Price	Buy
256279	1mg	$296	Buy
BRS0000669	5MG	$755.95	Buy
B5249	1mg	$108	Buy

PL017 Chemical Properties,Uses,Production

Biological Activity

PL-017 is a potent and selective μ opioid receptor agonist with IC50 of 5.5 nM for 125I-FK 33,824 binding to the μ site. PL-017 produces durable and reversible analgesia in rats.

in vitro

PL-017 has an IC ₅₀ of 10000 nM for ¹²⁵ I-DADLE binding to δ site.

in vivo

PL-017 (0.22, 0.45, 0.9 nmol/rat; icv) has the time of maximum effect of approximately 15 to 30 mm after injection at lower doses and produces analgesia lasting as long as 4 hours with larger doses in male Sprague-Dawley rats weighing 250 to 375 g.

target

IC50: 5.5 nM ( ¹²⁵ I-FK 33,824 binding to μ site)

PL017 Preparation Products And Raw materials

Raw materials

Preparation Products

PL017 Suppliers

Global( 48)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696;	info@hanhongsci.com	China	42982	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
Nanjing Leon Biological Technology Co., Ltd.	17705183659	sales@njleonbiotech.com	China	5503	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 13082558573	liugang@njpeptide.com	China	9961	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919	eric@peptidego.com	China	6119	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
Career Henan Chemica Co	58
Chengdu Youngshe Chemical Co., Ltd.	58
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58

View Lastest Price from PL017 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-10-11	(N-Me-Phe3,D-Pro4)-β-Casomorphin (1-4) amide (bovine) 83397-56-2	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

(N-Me-Phe3,D-Pro4)-β-Casomorphin (1-4) amide (bovine)
83397-56-2
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

83397-56-2(PL017)Related Search:

PL017-dynorphin A (6-17) PL017, BOVINE, TRIFLUOROACETATE SALT D-Prolinamide (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE PL017

(N-ME-PHE3,D-PRO4)-BETA-CASOMORPHIN (1-4) AMIDE (BOVINE) [N-ME-PHE3, D-PRO4]-MORPHICEPTIN [(NME)PHE3, DPRO4] MORPHICEPTIN, BOVINE PL017 TYR-PRO-(NME)PHE-DPRO-NH2 H-TYR-PRO-N-ME-PHE-D-PRO-NH2 {N-METHYL-PHE3,D-PRO4}-BETA-CASOMORPHIN FRAGMENT 1- [n-methyl-phe3, d-pro4]-β-casomorphin fragment 1-4 amide, bovine morphiceptin, N-Me-Phe(3)- [NMPhe3,D-Pro4]morphiceptin L-Tyr-L-Pro-N-Methyl-L-Phe-D-Pro-NH2 [NMePhe3, DPro4] b-Casomorphin: 1-4, amide, bovine (N-Me-Phe3,D-Pro4)-β-Casomorphin (1-4) amide (bovine) D-Prolinamide, L-tyrosyl-L-prolyl-N-methyl-L-phenylalanyl- 83397-56-2 C29H37N5O5 Amino Acids and Peptides Biochemicals and Reagents BioChemical Peptides Other Peptides