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quinaldopeptin

CAS No.
130743-07-6
Chemical Name:
quinaldopeptin
Synonyms
quinaldopeptin;BMY 28662, BU 3845T;Quinaldopeptin (9CI)
CBNumber:
CB51318925
Molecular Formula:
C62H78N14O14
Molecular Weight:
1243.38
MDL Number:
MFCD08061897
MOL File:
130743-07-6.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

quinaldopeptin Properties

Density 1.45±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: slightly soluble; Methanol: slightly soluble
form Yellow powder.
pka 6.91±0.40(Predicted)

quinaldopeptin price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 28167 Quinaldopeptin 130743-07-6 500μg $401 2024-03-01 Buy
Cayman Chemical 28167 Quinaldopeptin 130743-07-6 2.5mg $1502 2024-03-01 Buy
Usbiological Q0965 Quinaldopeptin 130743-07-6 500ug $582 2021-12-16 Buy
American Custom Chemicals Corporation API0019178 QUINALDOPEPTIN 95.00% 130743-07-6 0.5MG $646 2021-12-16 Buy
Product number Packaging Price Buy
28167 500μg $401 Buy
28167 2.5mg $1502 Buy
Q0965 500ug $582 Buy
API0019178 0.5MG $646 Buy

quinaldopeptin Chemical Properties,Uses,Production

Description

Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).

Uses

Quinaldopeptin is a bis-intercalating cyclic peptide antibiotic.

Uses

Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated with a murine tumour, and also shows weak nematocidal activity. Quinaldopeptin is related to the luzopeptins and sandramycin.

quinaldopeptin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55717 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
quinaldopeptin BMY 28662, BU 3845T Quinaldopeptin (9CI) 130743-07-6