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defibrotide

CAS No.
83712-60-1
Chemical Name:
defibrotide
Synonyms
Dasovas;Noravid;Prociclide;Fraction p;defibrotide;Defibrinotide;Defibrotide Sodium;defibrotide USP/EP/BP;Defibrotide Impurity 2;Defibrotide sodium (Defitelio)
CBNumber:
CB51358215
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2022-12-21 16:56:50

defibrotide Properties

EWG's Food Scores 1
FDA UNII DEFIBROTIDE (BOVINE) (438HCF2X0M)
DEFIBROTIDE SODIUM (L7CHH2B2J0)
ATC code B01AX01

SAFETY

Risk and Safety Statements

Toxicity LD50 intraperitoneal in dog: > 600mg/kg

defibrotide Chemical Properties,Uses,Production

Description

Defibrotide is an antithrornbotic, partially-depolymerized polydeoxyribonucleotide obtained from bovine lungs. It is reported to be useful in the treatment of myocardial and severe lower limb ischemia, renal failure due to thrombotic microangiopathy, and thrombophlebitis, and in the prophylaxis of deep vein thrombosis, possibly via PCI2 stimulation.

Originator

Crinos (Italy)

brand name

NORAVID; PROCICLIDE

defibrotide Preparation Products And Raw materials

Raw materials

Preparation Products

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defibrotide Dasovas Defibrinotide Fraction p Noravid Prociclide defibrotide USP/EP/BP Defibrotide Impurity 2 Defibrotide Sodium Defibrotide sodium (Defitelio) 83712-60-1