TOSUFLOXACIN TOSILATE
- CAS No.
- 100490-36-6
- Chemical Name:
- TOSUFLOXACIN TOSILATE
- Synonyms
- Ozex;TFLX;a67107;a61827;A-60969;Toskisasin;Aids007807;Aids-007807;abbott61827;108138-46-1 (Deleted)
- CBNumber:
- CB5138403
- Molecular Formula:
- C19H15F3N4O3
- Molecular Weight:
- 404.34
- MDL Number:
- MFCD00865059
- MOL File:
- 100490-36-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Tosufloxacin | T549503 | 50mg | $695 |
| Tosufloxacin | T549503 | 10mg | $150 |
| TOSUFLOXACIN 95.00% | API0004457 | 250MG | $241.5 |
| TOSUFLOXACIN 95.00% | API0004457 | 1G | $945.95 |
| Tosufloxacintosilate | 18794 | 25mg | $1500 |
| Boiling point | 614.4±55.0 °C(Predicted) |
|---|---|
| Density | 1.558±0.06 g/cm3(Predicted) |
| pka | 5.79±0.70(Predicted) |
| InChI | InChI=1S/C19H15F3N4O3/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29) |
| InChIKey | WUWFMDMBOJLQIV-UHFFFAOYSA-N |
| SMILES | N1(C2=CC=C(F)C=C2F)C2C(=CC(F)=C(N3CCC(N)C3)N=2)C(=O)C(C(O)=O)=C1 |
| CAS DataBase Reference | 100490-36-6(CAS DataBase Reference) |
| FDA UNII | GHJ553KQPS |
TOSUFLOXACIN TOSILATE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T549503 | Tosufloxacin | 100490-36-6 | 50mg | $695 | 2021-12-16 | Buy |
| TRC | T549503 | Tosufloxacin | 100490-36-6 | 10mg | $150 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004457 | TOSUFLOXACIN 95.00% | 100490-36-6 | 250MG | $241.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004457 | TOSUFLOXACIN 95.00% | 100490-36-6 | 1G | $945.95 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 18794 | Tosufloxacintosilate | 100490-36-6 | 25mg | $1500 | 2021-12-16 | Buy |
TOSUFLOXACIN TOSILATE Chemical Properties,Uses,Production
Uses
Tosufloxacin Tosilate (CAS# 100490-36-6) was identified in a Haemophilus influenza clone ST422.
Definition
ChEBI: 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is a 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 3-aminopyrrolidin-1-yl substituents at positions 1, 6 and 7 respectively. It is a 1,8-naphthyridine derivative, an amino acid, a monocarboxylic acid, an organofluorine compound, an aminopyrrolidine, a tertiary amino compound, a primary amino compound and a quinolone antibiotic. It is a conjugate base of a 1-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]pyrrolidin-3-aminium.
in vivo
Tosufloxacin tosylate hydrate (T-3262) (oral gavage; 0.16-13.39 mg/kg; once) treatment shows antibacterial activity against S. aureus, E. coli, and P. aeruginosa in vivo[2].
| Animal Model: | Male Slc:ICR mice infected with S. aureus[2] |
| Dosage: | 1.27-2.15 mg/kg |
| Administration: | Oral gavage; 1.27-2.15 mg/kg; once |
| Result: | Showed 50% effective dose (ED50) of 1.62 mg/kg (body weight) at 7 days after infection. Showed MIC value of 0.0125 μg/mL. |
| Animal Model: | Male Slc:ICR mice infected with E. coli[2] |
| Dosage: | 0.16-0.30 mg/kg |
| Administration: | Oral gavage; 0.16-0.30 mg/kg; once |
| Result: | Showed 50% effective dose (ED50) of 0.22 mg/kg (body weight) at 7 days after infection. Showed MIC value of 0.0125 μg/mL. |
| Animal Model: | Male Slc:ICR mice infected with P. aeruginosa[2] |
| Dosage: | 7.66-13.39 mg/kg |
| Administration: | Oral gavage; 7.66-13.39 mg/kg; once |
| Result: | Showed 50% effective dose (ED50) of 10.13 mg/kg (body weight) at 7 days after infection. Showed MIC value of 0.78 μg/mL. |
IC 50
Quinolone
TOSUFLOXACIN TOSILATE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
TOSUFLOXACIN TOSILATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20034 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24727 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2123 | 70 |
| Aikon International Limited | 025-58859352 18068836627 | sales01@aikonchem.com | China | 16027 | 58 |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4181 | 58 |
View Lastest Price from TOSUFLOXACIN TOSILATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | TOSUFLOXACIN TOSILATE USP/EP/BP
100490-36-6
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-02-12 | TOSUFLOXACIN TOSILATE
100490-36-6
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- TOSUFLOXACIN TOSILATE USP/EP/BP
100490-36-6
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- TOSUFLOXACIN TOSILATE
100490-36-6
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
