Ubiquinol
- CAS No.
- 992-78-9
- Chemical Name:
- Ubiquinol
- Synonyms
- CoQH2-10;Ubiquinol 50;Water Soluble Q10;Dihydrocoenzyme Q10;Ubiquinol (1705334);Reduced Coenzyme Q10;Reduced ubiquinone-10;Reduced Ubiquinone Q10;coenzyme Q10 (Ubiquinol);Coenzyme Q10-hydroquinone
- CBNumber:
- CB51417992
- Molecular Formula:
- C59H92O4
- Molecular Weight:
- 865.36
- MDL Number:
- MFCD11973816
- MOL File:
- 992-78-9.mol
| Melting point | 48-49°C |
|---|---|
| Boiling point | 866.9±65.0 °C(Predicted) |
| Density | 0.951±0.06 g/cm3(Predicted) |
| storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform: soluble |
| form | A crystalline solid |
| pka | 10.53±0.50(Predicted) |
| InChIKey | QNTNKSLOFHEFPK-UPTCCGCDSA-N |
| SMILES | C1(O)=C(OC)C(OC)=C(O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C |
| FDA UNII | M9NL0C577Y |
Ubiquinol price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19677 | Ubiquinol ≥90% | 992-78-9 | 500μg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 19677 | Ubiquinol ≥90% | 992-78-9 | 1mg | $218 | 2024-03-01 | Buy |
| Cayman Chemical | 19677 | Ubiquinol ≥90% | 992-78-9 | 5mg | $961 | 2024-03-01 | Buy |
| Cayman Chemical | 19677 | Ubiquinol ≥90% | 992-78-9 | 10mg | $1681 | 2024-03-01 | Buy |
| TRC | U700500 | Ubiquinol | 992-78-9 | 1mg | $65 | 2021-12-16 | Buy |
Ubiquinol Chemical Properties,Uses,Production
Description
Ubiquinol is a reduced form of coenzyme Q10 (CoQ10; ), which exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol). CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex. CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis.
Chemical Properties
Light Yellow-Orange Solid
Uses
Reduced coenzyme Q for improving nervous system cell functions.
Definition
ChEBI: Ubiquinol-10 is a ubiquinol in which the polyprenyl substituent is decaprenyl. It has a role as a metabolite and a biomarker. It is a polyprenylhydroquinone and an ubiquinol.
benefits
The reduced form of CoQ10, ubiquinol, is a powerful lipid-soluble antioxidant that provides critical antioxidant protection in the lymph and blood throughout the body. Ubiquinol is the only known fat-soluble antioxidant that human cells can synthesize. In its reduced form, ubiquinol coenzyme Q10 plays a significant role in preventing oxidation in both the lipids that make up much of the structure of cellular membranes in cells throughout the body and also in lipoprotein lipids present in circulation. Coenzyme Q10 can also recycle or regenerate other antioxidants such as vitamin E7 and vitamin C. Ubiquinol plays a critical role in mitochondria by protecting mitochondrial membranes and mitochondrial DNA (mtDNA) from free radical damage[1].
Side effects
Coenzyme Q10 supplements appear to be safe and produce few side effects when taken as directed. Mild side effects might include digestive problems such as: Upper abdominal pain, Loss of appetite, Nausea and vomiting, and Diarrhea.
Other possible side effects may include Headaches and dizziness, Insomnia, Fatigue, Skin itching or rashes, and Irritability or agitation.
References
[1] Pelton, Ross. “Coenzyme Q10: A Miracle Nutrient Advances in Understanding.” Integrative medicine 19 2 (2020): 16–20.
Ubiquinol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Leading Chemical and Trading Co.,Ltd | +8615669938129 | sales@leadingchemical.com | China | 121 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Wuhan Nutra Biotechnology Co.,Ltd | +8617786394783 | nutrabiotech@outlook.com | China | 300 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9571 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9339 | 58 |
| Shandong Zhishang New Material Co., Ltd. | +8617653113209 | sales002@sdzschem.com | China | 3050 | 58 |
Related articles
- What is Ubiquinol?
- Ubiquinol, also known as ubiquinol-10, is the fully reduced form of coenzyme Q10. It is produced in mitochondria and has the a....
- Apr 11，2024
View Lastest Price from Ubiquinol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-06-15 | UBIQUINOL
992-78-9
|
US $145.00 / KG | 1KG | 10% | 1000KG | Baoji Guokang Bio-Technology Co., Ltd. | |
 |
2021-07-13 | UBIQUINOL
992-78-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | UBIQUINOL
992-78-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |