ChemicalBook >> CAS DataBase List >>2,2,2-Trifluoroethyl trifluoromethanesulfonate

2,2,2-Trifluoroethyl trifluoromethanesulfonate

CAS No.
6226-25-1
Chemical Name:
2,2,2-Trifluoroethyl trifluoromethanesulfonate
Synonyms
2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULPHONATE;2,2,2-TRIFLUOROETHYL TRIFLATE;TFOL-TF;2,2,2-Trifluoroethyl Triflante;2,2,2-Trifluoroethyl trifluoromethanesulf;2-Trifluoroethyl trifluoromethanesulfonate;2,2,2-Trifluoroethyl trifluoromethanesulfote;2,2,2-Trifluoroethytrifluoromethanesulfonate;2,2,2-Trifluoroethyl trifluoroMethylsulfonate;2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULFONATE
CBNumber:
CB5142808
Molecular Formula:
C3H2F6O3S
Molecular Weight:
232.1
MDL Number:
MFCD00671579
MOL File:
6226-25-1.mol
MSDS File:
SDS
Last updated:2024-03-13 09:24:55

2,2,2-Trifluoroethyl trifluoromethanesulfonate Properties

Boiling point 89-91°C
Density 1,61 g/cm3
refractive index 1.3037
RTECS PB2775000
Flash point >110°(230°F)
storage temp. 2-8°C
solubility Chloroform, Methanol (Slightly)
form Liquid
color Colorless to yellow
Water Solubility Slightly soluble in water.
Sensitive Moisture Sensitive
InChIKey RTMMSCJWQYWMNK-UHFFFAOYSA-N
CAS DataBase Reference 6226-25-1(CAS DataBase Reference)
EPA Substance Registry System Methanesulfonic acid, trifluoro-, 2,2,2-trifluoroethyl ester (6226-25-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H314-H330
Precautionary statements  P260-P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  Xi,T,C
Risk Statements  36/37/38-34-23/25
Safety Statements  26-36/37/39-45
RIDADR  3265
WGK Germany  3
Hazard Note  Irritant
HazardClass  TOXIC, CORROSIVE
HazardClass  8
PackingGroup 
HS Code  29055900
NFPA 704
1
3 0

2,2,2-Trifluoroethyl trifluoromethanesulfonate price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 752924 2,2,2-Trifluoroethyl trifluoromethanesulfonate 95% 6226-25-1 5g $135 2024-03-01 Buy
TCI Chemical T1604 2,2,2-Trifluoroethyl Trifluoromethanesulfonate >97.0%(GC) 6226-25-1 5g $142 2024-03-01 Buy
TCI Chemical T1604 2,2,2-Trifluoroethyl Trifluoromethanesulfonate >97.0%(GC) 6226-25-1 25g $354 2024-03-01 Buy
Alfa Aesar H61603 2,2,2-Trifluoroethyl trifluoromethanesulfonate, 95% 6226-25-1 5g $128.65 2024-03-01 Buy
Alfa Aesar H61603 2,2,2-Trifluoroethyl trifluoromethanesulfonate, 95% 6226-25-1 25g $462.65 2024-03-01 Buy
Product number Packaging Price Buy
752924 5g $135 Buy
T1604 5g $142 Buy
T1604 25g $354 Buy
H61603 5g $128.65 Buy
H61603 25g $462.65 Buy

2,2,2-Trifluoroethyl trifluoromethanesulfonate Chemical Properties,Uses,Production

Uses

A fluorine-containing alkyl alkanesulfonate with cyctotoxity towards cultured leukemia L1210 cells.

Uses

2,2,2-Trifluoroethyl trifluoromethanesulfonate is a powerful trifluoroethylating agent which is useful for synthesis of fluorinated amino acids. It is used as a reagent in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines.

Uses

Reagent used in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines

Synthesis

In a 100-ml flask equipped with a stirrer, a thermometer, a nitrogen introducing pipe, and a condenser, 50 ml (0.297 mol) of trifluoromethane sulfonic anhydride and 25 ml (0.342 moles) of 2,2,2-trifluoroethanol were placed at room temperature and stirred for 30 minutes in a nitrogen atmosphere, followed by reflux for 3 hours. After distillation, 50.3 g of 2,2,2-trifluoroethyl trifluoromethanesulfonate was obtained in a yield of 73%.
2,2,2-Trifluoroethyl trifluoromethanesulfonate

75-89-8
15458-53-4
6226-25-1
Synthesis of 2,2,2-Trifluoroethyl trifluoromethanesulfonate from 2,2,2-Trifluoroethanol and Trifluoromethanesulfonyl bromide
Global( 301)Suppliers
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Allfluoro pharmaceutical co. ltd.
021-26137118 +8615821363818 sales@allfluoro.com China 5791 58
Jiangxi Time Chemical CO Ltd
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Fluoropharm Co., Ltd.
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Jinan Carbotang Biotech Co.,Ltd.
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View Lastest Price from 2,2,2-Trifluoroethyl trifluoromethanesulfonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2,2-Trifluoroethyl trifluoromethanesulfonate pictures 2023-03-10 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
US $0.00 / KG 1KG 99.0% 1000KG LY Global chemicals co.,ltd .
2,2,2-Trifluoroethyl trifluoromethanesulfonate pictures 2022-10-10 2,2,2-Trifluoroethyl trifluoromethanesulfonate
6226-25-1
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2,2,2-Trifluoroethyl Trifluoromethanesulfonate pictures 2021-07-13 2,2,2-Trifluoroethyl Trifluoromethanesulfonate
6226-25-1
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2,2,2-trifluoroethyltrifluorometanesulfonicacid methanesulfonicacid,trifluoro-,2,2,2-trifluoroethylester TRIFLUOROMETHANESULFONIC ACID 2,2,2-TRIFLUOROETHYL ESTER TFOL-TF 2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULFONATE 2,2,2-Trifluoroethyltrifluoromethanesulphonate97% TRIFLUOROMETHANESULPHONICACID2,2,2-TRIFLUOROETHYLESTER 2,2,2 Trifluoroethyl TrifluoroMathane sulfonate 2,2,2-Trifluoroethyl trifluoromethanesulphonate 97% 2,2,2-Trifluoroethanol TrifluoroMethanesulfonate 2,2,2-Trifluoroethyl trifluoroMethylsulfonate 2,2,2-Trifluoroethyl Triflate Trifluoromethanesulfonic Acid 2,2,2-Trifluoroethyl Ester 2,2,2-Trifluoroethyl trifluoromethanesulfote 2-Trifluoroethyl trifluoromethanesulfonate Trifluoromethane sulfonate trifluoroethyl ester 2,2,2-Trifluoroethytrifluoromethanesulfonate 1,1,1-Trifluoro-2,2,2-trifluoroethyl Ester Methanesulfonic Acid Methanesulfonic acid, 1,1,1-trifluoro-, 2,2,2-trifluoroethyl ester High purity CAS 6226-25-1 2,2,2-Trifluoroethyl trifluoromethanesulfonate in stock 2,2,2-TRIFLUOROETHYL TRIFLATE 2,2,2-TRIFLUOROETHYL TRIFLUOROMETHANESULPHONATE 2,2,2-TRIFLUOROETHYL TRIFLATE 2,2,2-Trifluoroethyl Trifluoromethanesulfonate 2,2,2-Trifluoroethyl Triflante 2,2,2-Trifluoroethyl trifluoromethanesulf 6226-25-1 56226-25-1 C3H2F6O3S Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Fluorinated Building Blocks Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds Fluorinated Building Blocks Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Synthetic Organic Chemistry R00001