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Ufiprazole

CAS No.
73590-85-9
Chemical Name:
Ufiprazole
Synonyms
e SuL;H 168/22;CB5146932;ufiprazole;Pyrmetazol;PyrMetazole;Omeprazolesulfide;OMEPRAZOLE SULPHIDE;Omeprazole EP Imp C;Omeprazole Impurity C
CBNumber:
CB5146932
Molecular Formula:
C17H19N3O2S
Molecular Weight:
329.42
MDL Number:
MFCD00869021
MOL File:
73590-85-9.mol
Modify Date:2022-08-20 16:03:36

Ufiprazole Properties

Melting point 122.0 to 126.0 °C
Boiling point 539.7±60.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 9.81±0.10(Predicted)
color White to Off-White
λmax 307nm(MeOH)(lit.)
InChIKey XURCIPRUUASYLR-UHFFFAOYSA-N
CAS DataBase Reference 73590-85-9(CAS DataBase Reference)
FDA UNII 6FFV1V867C

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HS Code  29339900

Ufiprazole price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical O0437 Omeprazole Sulfide >98.0%(HPLC)(T) 73590-85-9 200mg $158 2022-04-27 Buy
TCI Chemical O0437 Omeprazole Sulfide >98.0%(HPLC)(T) 73590-85-9 1g $397 2022-04-27 Buy
Cayman Chemical 18885 Omeprazole sulfide ≥98% 73590-85-9 100mg $54 2022-04-27 Buy
Cayman Chemical 18885 Omeprazole sulfide ≥98% 73590-85-9 1g $399 2022-04-27 Buy
Cayman Chemical 18885 Omeprazole sulfide ≥98% 73590-85-9 250mg $126 2022-04-27 Buy
Product number Packaging Price Buy
O0437 200mg $158 Buy
O0437 1g $397 Buy
18885 100mg $54 Buy
18885 1g $399 Buy
18885 250mg $126 Buy

Ufiprazole Chemical Properties,Uses,Production

Synthesis

Ufiprazole can be synthesized by the condensation reaction of 2-mercapto-5-methoxybenzimidazole and 2-chloromethyl-4-methoxy-3,5-lutidine.

Description

Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole . As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 μM).

Uses

Omeprazole Sulfide (Esomeprazol EP Impurity C(Omeprazole EP Impurity C)) is a metabolite of Omeprazole.

Uses

A metabolite of Omeprazole

Biological Activity

Ufiprazole (Omeprazole sulfide) is an intermediate in the production of gastric proton pump inhibitors omeprazole and esomeprazole.

37052-78-1
84006-10-0
73590-85-9
Synthesis of Ufiprazole from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE and 2-(Chloromethyl)-3,5-dimethyl-4-methoxypyridine

Ufiprazole Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 443)Suppliers
Supplier Tel Email Country ProdList Advantage
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9992 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29803 60
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1815 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 22021 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1809 55
Guangzhou PI PI Biotech Inc
+86-020-81716320 +86-18371201331 Sales@pipitech.com China 3640 55
ATK CHEMICAL COMPANY LIMITED
21-51619050 ivan@atkchemical.com China 30656 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29960 58
Shanghai Arbor Chemical Co., Ltd.
021-60451682 act@arborchemical.com CHINA 906 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254 linda@hubeijusheng.com CHINA 28229 58

View Lastest Price from Ufiprazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2022-06-08 Ufiprazole
73590-85-9
US $55.00-43.00 / KG 1KG 99% 9000kg/per week Hebei Lingding Biological Technology Co., Ltd
2022-03-25 ufiprazole
73590-85-9
US $10.00 / kg 1kg 0.99 10tons Henan Guange Biotechnology Co. LTD
2021-11-23 Omeprazole sulfide
73590-85-9
US $100.00 / KG 500KG ≥98% 100tons Qiuxian Baitai New Material Co., LTD
  • Ufiprazole
    73590-85-9
  • US $55.00-43.00 / KG
  • 99%
  • Hebei Lingding Biological Technology Co., Ltd
  • ufiprazole
    73590-85-9
  • US $10.00 / kg
  • 0.99
  • Henan Guange Biotechnology Co. LTD
5-Methoxy-2-[[(4-Methxoy-3,5-diMethylpyridin-2-yl)Methyl]sulfanyl]-1H-benziMidazole(ufiprazole) 2-[(3,5-Dimethyl-4-methoxy-2-pyridyl)methylthio]-5-methoxy-1H-benzimidazole 2-[[(3,5-Dimethyl-4-methoxy-2-pyridyl)methyl]thio]-5-methoxy-1H-benzimidazole 5-Methoxy-2-[(3,5-dimethyl-4-methoxy-2-pyridyl)methylthio]-1H-benzimidazole 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL) THIO]-1H-BENZIMIDAZOLE ((OMEPRAZOLE SULPHIDE COMPOUND) 6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylthio]-1H-benzimidazole 6-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfanyl]-1H-benzimidazole 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfanyl]-1H-benzimidazole 1H-BenziMidazole, 6-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]- EsoMeprazol iMpurity C OMeprazole IMpurity-C(EP) 6-Methoxy-2-((4-Methoxy-3,5-diMethylpyridin-2-yl)Methylthio)-1H-benzo[d]iMidazole IMp. C (EP): 5-Methoxy-2-[[(4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl]- sulphanyl]-1H-benziMidazole (Ufiprazole) EsoMeprazole EP IMpurity C EsoMeprazole IMp.C ep. 5-Methoxy-2-(4-Methoxy-3,5-diMethyl-pyridin-2-ylMethylsulfanyl)-1H-benzoiMidazole 5-Methoxy-2-[[(4-Methxoy-3,5-diMethylpyridin-2-yl)Methyl]sulfanyl]-1H-benziMidazole 5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE 5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLMERCAPTOBENZIMIDAZOLE 5-METHOXY-2-[[(3,5-DIMETHYL-4-METHOXY PYRIDINYL)-METHYL]THIO]-1H-BENZIMIDAZOLE 2-[(4-METHOXYETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLTHIO]-5-METHOXYBENZIMIDAZOLE 2-{[(3,5-dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1h-benzimidazole OMEPRAZOLE SULPHIDE H 168/22 ufiprazole 5-METHOXY-2-(4-METHOXYL-3,5-DIMETHYL-PYRIDINE-2-YLMETHYLSULFENYL)- 1H- BENZIMIDA Omeprazolesulfide 5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLTHIO-1H-BENZIMIDAZOLE(UFIPRAZOLE) 2-{[(3,5-Dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1H benzimi 5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE =98% (1R,2S,5R)-menthyl-5(s)-cytosin-1-yl-1,3-oxathiolane-2R-carboxylate(CME) 5-METHOXY-2-{[(3,5-DIMETHYL-4-METHOXY-2-PYRIDINYL)METHYL]THIO}-1H-BENZIMIDAZOLE (OMEPRAZOLE SULFIDE) (1R,2S,5R)-MENTHYL-5(S)-CYTOSINE-1-YL-[1,3]-OXATHIOLANE-2R-CARBOXYLATE ( IR, 2S, 5R)-menthyl C5(s)-cytosin C1-yl-[1,3] Coxathiolane-2R-carboxylate (CME) 5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE) 5-Methoxy-2-((4-Methoxy-3,5-diMethylpyridin-2-yl)Methylthio)-1H-benziMidazol EsoMeprazo interMediate B Omeprazole Sulfur ether Esomeprazole Magnesium Trihydrate Imp. C (EP): 5-Methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-sulphanyl]-1H-benzimidazole (Ufiprazole) Omeprazole impurity C (PhEur) Pyrmetazol CB5146932 Omeprazole metabolite Omeprazole sulfide Omeprazole Sulfide (Ufiprazole) 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulphanyl)-1H-benzimidazole Esomeprazole impurity C Omeprazole Impurity C 5-METHOXY-2-[[(3,5-DIMETHYL-4-METHOXY PYRIDINYL)-METHYL]THIO]-1H BENZIMIDAZOLE(OMEPRAZOLE SULPHIDE) 2-[[(3,5-DiMethyl-4-Methoxy-2-pyridyl)Methyl]thio]-5-MethoxybenziMidazole 6-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole PyrMetazole Ufiprazole, OMeprazole Sulphide EsoMeprazole related substance C 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole Esomeprazole EP Impurity C(Omeprazole EP Impurity C) 2-[ [(4-methoxy-3,5-dimethylpyridine-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole Omeprazole Sulfide Esomeprazole EP Impurity C / (Omeprazole Sodium EP Impurity C) 2-[(4-methoxy--3,5-dimethyl-2-pyridinyl-)-methyl-thio]-5-methoxy--benz-imidazole