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Phenobarbital sodium

Phenobarbital sodium structure

CAS No.: 57-30-7

Chemical Name:: Phenobarbital sodium

Synonyms: sodiumluminal;LUMINAL SODIUM;gardenalsodium;phenobalsodium;phenobarbitalna;solphenobarbital;solphenobarbitone;LUMINAL SODIUM SALT;fenobarbitalnatrium;phenobarbitalelixir

CBNumber:: CB5147742

Molecular Formula:: C12H12N2O3.Na

Molecular Weight:: 254.22

MDL Number:: MFCD00036211

MOL File:: 57-30-7.mol

MSDS File:: SDS

Last updated:2023-05-15 10:43:58

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Phenobarbital sodium Properties

Melting point	175°C
solubility	H₂O: 1 g/mL
form	Solid
color	White to Off-White
PH	pH (100g/l, 25℃) : 9.0～11.0
Water Solubility	>=10 g/100 mL at 20 ºC
Merck	13,7319
BRN	3802044
Stability	Hygroscopic
CAS DataBase Reference	57-30-7(CAS DataBase Reference)
FDA UNII	SW9M9BB5K3
EPA Substance Registry System	Phenobarbital sodium (57-30-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06,GHS08
Signal word	Danger
Hazard statements	H301-H317-H351
Precautionary statements	P202-P261-P264-P280-P301+P310-P302+P352
Hazard Codes	T
Risk Statements	25-40-43
Safety Statements	22-36/37/39-45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	-
RTECS	CQ7000000
HazardClass	6.1(b)
PackingGroup	III
Toxicity	LD50 orally in rats: 660 mg/kg (Schaffarzick, Brown)

Phenobarbital sodium price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P5178	Phenobarbital sodium salt	57-30-7	25g	$92.7	2024-03-01	Buy
American Custom Chemicals Corporation	API0003812	PHENOBARBITAL SODIUM 95.00%	57-30-7	25G	$1157.45	2021-12-16	Buy
AHH	MT-57842	Phenobarbitalsodium 97%	57-30-7	500g	$420	2021-12-16	Buy

Product number	Packaging	Price	Buy
P5178	25g	$92.7	Buy
API0003812	25G	$1157.45	Buy
MT-57842	500g	$420	Buy

Phenobarbital sodium Chemical Properties,Uses,Production

Chemical Properties

Solution S is clear (2.2.1) and not more intensely coloured than reference solution Y7 (2.2.2, Method II).

Uses

Phenobarbital sodium salt has been used:

to anesthetize mice for inducing ischemia-reperfusion injury
as a positive control for the activation of constitutive androstane receptor (CAR)
in bioluminescent yeast bioreporters (BLYAS) assay

Uses

Anticonvulsant; sedative-hypnotic.

Definition

ChEBI: A barbiturate that is the sodium salt of phenobarbital (barbituric acid substituted at C-5 by ethyl and phenyl groups).

brand name

Luminal Sodium (Sterling Winthrop).

General Description

Odorless white crystalline powder. Aqueous solutions are alkaline to litmus and phenolphthalein (pH approximately 9.3). Bitter taste. A narcotic.

Air & Water Reactions

Hygroscopic. May be sensitive to prolonged exposure to air. Water soluble. Aqueous solutions are unstable, but may be kept at or below 50°F for a few days.

Reactivity Profile

Phenobarbital sodium can react with strong oxidizing agents. Incompatible with ammonium salts and chloral hydrate. Also incompatible with acids and acidic substances .

Fire Hazard

Flash point data for Phenobarbital sodium are not available; however, Phenobarbital sodium is probably combustible.

Biochem/physiol Actions

Phenobarbital, a substituted barbituric acid is an antileptic drug and is not easily eliminated from circulation. It hyperpolarizes the synaptic neuronal membranes by favoring the activation of neuronal postsynaptic GABAA?receptors by γ aminobutyric acid (GABA). Phenobarbital is also effective in treating neonatal seizures and status epilepticus.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intravenous, intraperitoneal, intraduodenal, and subcutaneous routes. Human systemic effects by ingestion: nausea or vomiting and coma. Experimental reproductive effects. Mutation data reported. Used to treat epilepsy, as a hypnotic and sedative. When heated to decomposition it emits toxic fumes of NOx and NazO. See also BARBITURATES

Phenobarbital sodium synthesis

Synthesis of Phenobarbital sodium from Phenobarbital

Phenobarbital sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Phenobarbital 1(2H)-Pyrimidinebutanoic acid, 5-ethyltetrahydro-2,4,6-trioxo-5-phenyl-, ethyl ester

Phenobarbital sodium Suppliers

Global( 77)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
Hebei Duling International Trade Co. LTD	+8618032673083	sales05@hbduling.cn	China	15745	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32360	55
Chemwill Asia Co.,Ltd.	86-21-51086038	chemwill_asia@126.com	CHINA	23931	58
Fujian Mindong force Jiexun Pharmaceutical Co., Ltd.	0591-83310368		China	12	60
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28398	80
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810	sales@sunlidabio.com	China	3750	55

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Antai Fine Chemical Technology Co.,Limited	58
Dideu Industries Group Limited	58
Hebei Duling International Trade Co. LTD	58
Mainchem Co., Ltd.	55
Chemwill Asia Co.,Ltd.	58
Fujian Mindong force Jiexun Pharmaceutical Co., Ltd.	60
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
Nanjing Sunlida Biological Technology Co., Ltd.	55

View Lastest Price from Phenobarbital sodium manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-07-29	Phenobarbital sodium USP/EP/BP 57-30-7	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited
	2019-12-26	Phenobarbital sodium 57-30-7	US $1.00 / g	1g	≥98%	g/kg/Ton	Career Henan Chemical Co

Phenobarbital sodium USP/EP/BP
57-30-7
US $1.10 / g
99.9%
Dideu Industries Group Limited

Phenobarbital sodium
57-30-7
US $1.00 / g
≥98%
Career Henan Chemical Co

57-30-7(Phenobarbital sodium )Related Search:

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PHENYL VALERATE Ethyl cellulose 2-Phenylphenol

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solublephenobarbitone LUMINAL SODIUM LUMINAL SODIUM SALT 5-ETHYL-5-PHENYL-2,4,6-TRIOXOHEXAHYDROPYRIMIDINE SODIUM SALT 5-ETHYL-5-PHENYLBARBITURIC ACID SODIUM SALT 5-ethyl-5-phenyl-2,4,6-(1h,3h,5h)pyrimidinetrione monosodium salt SODIUM 5-ETHYL-5-PHENYLBARBITURATE PHENOBARBITAL SODIUM PHENOBARBITAL SODIUM SALT PHENOBARBITONE SODIUM PHENOBARBITAL, SODIUM--DEA SCHEDULE*IV I TEM PHENOBARBITAL SODIUM ANESTHETIC,SEDATIVE ,H 4,6(1h,3h,5h)-pyrimidinetrione,5-ethyl-5-phenyl-monosodiumsalt 5-Ethyl-5-phenyl-2,4,6-trioxohexahydropyrimidine sodium salt, 5-Ethyl-5-phenylbarbituric acid sodium salt, Luminal sodium salt, Sodium 5-ethyl-5-phenylbarbiturate 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-, monosodium salt 5-Ethyl-5-phenylbarbituric acid sodium Sodium ethylphenylbarbiturat Phenobarbital Sodium Salt (contains 5% Isopropyl Alcohol at maximum) 5-Ethyl-5-phenyl-2-sodiooxy-4,6(1H,5H)-pyrimidinedione Phenobarbital sodium salt,5-Ethyl-5-phenyl-2,4,6-trioxohexahydropyrimidine sodium salt, 5-Ethyl-5-phenylbarbituric acid sodium salt, Luminal sodium salt, Sodium 5-ethyl-5-phenylbarbiturate Phenobarbital SodiuM API 2,4,6(1H,3H,5H)-PyriMidinetrione,5-ethyl-5-phenyl-, sodiuM salt (1:1) fenobarbitalnatrium PHENOBARBITALSODIUM,USP 5-ETHYL-5-PHENYLBARBITURICACIDSODIUMSALT(PHENOBARBITALSODIUM) 5-ethyl-5-phenyl-barbituricacisodiumsalt gardenalsodium phenobalsodium phenobarbitalelixir phenobarbitalna phenobarbitonesodiumsalt phenyl-aethyl-barbitursaeurenatrium phenylethylbarbituricacid,sodiumsalt sodiumluminal sodiumphenobarbital sodiumphenobarbitone sodiumphenylethylbarbiturate sodiumphenylethylmalonylurea solphenobarbital solphenobarbitone solublephenobarbital Phenobarbital sodium USP/EP/BP Pramoxine Impurity 11 57-30-7 C12H11N2O3Na C12H12N2O3Na Cell Signaling Enzymes Application Index Building Blocks Biochemicals and Reagents BioChemical Heterocyclic Building Blocks Enzymes, Inhibitors, and Substrates Xenobiotics and Drug Metabolism Substrates Pyrimidines Heterocyclic Compounds