STEM CELL FACTOR, HUMAN
- CAS No.
- 133352-98-4
- Chemical Name:
- STEM CELL FACTOR, HUMAN
- Synonyms
- RHSCF;HUMAN SF;HUMAN SCF;HUMAN MGF;SCF, HUMAN;REC SCF (HUMAN);C-KIT LIGAND HUMAN;HUMAN STEEL FACTOR;HUMAN C-KIT LIGAND;RECOMBINANT HUMAN SCF
- CBNumber:
- CB5149605
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00165757
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P261-P271 |
| Hazard Codes | Xi |
| Risk Statements | 36/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| HS Code | 2937190000 |
STEM CELL FACTOR, HUMAN price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S7901 | Stem Cell Factor human SCF, recombinant, expressed in E. coli, powder, suitable for cell culture | 133352-98-4 | 10μg | $480 | 2024-03-01 | Buy |
| Sigma-Aldrich | S7901 | Stem Cell Factor human SCF, recombinant, expressed in E. coli, powder, suitable for cell culture | 133352-98-4 | 50μg | $708 | 2024-03-01 | Buy |
| Sigma-Aldrich | H8416 | Stem Cell Factor human SCF, recombinant, expressed in HEK 293 cells, suitable for cell culture | 133352-98-4 | 10μg | $413 | 2024-03-01 | Buy |
| Sigma-Aldrich | H8416 | Stem Cell Factor human SCF, recombinant, expressed in HEK 293 cells, suitable for cell culture | 133352-98-4 | 5x10μg | $1650 | 2023-01-07 | Buy |
| Usbiological | 215475 | Stem Cell Factor, Human | 133352-98-4 | 5ug | $490 | 2021-12-16 | Buy |
STEM CELL FACTOR, HUMAN Chemical Properties,Uses,Production
General Description
The KITLG (KIT ligand) gene is mapped to human chromosome 12q21.32.
Biochem/physiol Actions
Stem Cell Factor (SCF), also known as c-Kit ligand (KL), steel factor (SLF) and mast cell growth factor (MGF), is a 30 kDa glycoprotein with broad activities on various tissues, including hematopoietic cells, pigment cells, and primordial germ cells. SCF is secreted by endothelial cells, fibroblasts, and bone marrow stromal cells as a membrane-bound form which may be cleaved to release the soluble form. Both forms are active in promoting colony formation from murine bone marrow cells, but membrane-bound SCF is more effective in promoting hematopoieses in vivo, suggesting a role in cellular interactions between hematopoietic and stromal cells. The soluble is thought to exist in solution as a noncovalently linked dimer. SCF is structurally related to M-CSF (CSF-1) and Flt-3/Flk-2 Ligand (FL) with all three sharing a similar size, existence of transmembrane and soluble forms, four conserved cysteines, and alternative splicing exon locations, but they share little sequence homology. SCF alone is a modest colony stimulating factor. However, in the presence of other cytokines such as EPO, TPO, GM-CSF, G-CSF, M-CSF, IL-3, and IL-7, SCF is a potent costimulant that works synergistically to increase the size of myeloid, erythroid or lymphoid lineage colonies without influencing the lineage differentiation of the progenitors.
STEM CELL FACTOR, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
STEM CELL FACTOR, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42959 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 | sales@klbio.cn | China | 9618 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | wulan@absin.cn | China | 24734 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10351 | 58 |
| Abmole Bioscience Inc. | 021-50967598 02150967598 | sales@abmole.cn | China | 4495 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
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