4-Nitrotoluene-2-sulfonic Acid
- CAS No.
- 121-03-9
- Chemical Name:
- 4-Nitrotoluene-2-sulfonic Acid
- Synonyms
- PNTOS;PNOTSA;4-Nitrotoluol-2-acid;LABOTEST-BB LT00052933;4-Nitro-2-sulfotoluene;5-nitro-o-toluenesulfonicac;5-nitro-o-toluenesulfonicaci;Toluenesulfonic acid, 5-nitr;4-Nitrotoluenesulfonic Acid;P-NITROTOLUENE SULFONIC ACID
- CBNumber:
- CB5153277
- Molecular Formula:
- C7H7NO5S
- Molecular Weight:
- 217.2
- MDL Number:
- MFCD00024914
- MOL File:
- 121-03-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Nitrotoluene-2-sulfonic Acid Hydrate >95.0%(T) | N0277 | 25g | $58 |
| 4-Nitrotoluene-2-sulfonic Acid Hydrate >95.0%(T) | N0277 | 500g | $315 |
| 5-Nitro-o-toluenesulfonicAcid | N572320 | 10g | $180 |
| 5-Nitro-o-toluenesulfonicAcid | N572320 | 100g | $275 |
| 5-Nitro-o-toluenesulfonicAcid | 60760 | 10g | $675 |
| More product size | |||
| Melting point | 135°C |
|---|---|
| Boiling point | 500°C (rough estimate) |
| Density | 1.6040 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 1.6100 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | -1.14±0.33(Predicted) |
| color | Very Dark Brown |
| Water Solubility | 667g/L at 23℃ |
| InChI | InChI=1S/C7H7NO5S/c1-5-2-3-6(8(9)10)4-7(5)14(11,12)13/h2-4H,1H3,(H,11,12,13) |
| InChIKey | ZDTXQHVBLWYPHS-UHFFFAOYSA-N |
| SMILES | C1(S(O)(=O)=O)=CC([N+]([O-])=O)=CC=C1C |
| CAS DataBase Reference | 121-03-9(CAS DataBase Reference) |
| FDA UNII | JBO1Z0PMOH |
| EPA Substance Registry System | Benzenesulfonic acid, 2-methyl-5-nitro- (121-03-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H412-H290 | |||||||||
| Precautionary statements | P501-P273-P260-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 34-41-43-36-22 | |||||||||
| Safety Statements | 26-36/37/39-39-36/37 | |||||||||
| RIDADR | 3261 | |||||||||
| RTECS | DB7175000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2904.99.4700 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| Hazardous Substances Data | 121-03-9(Hazardous Substances Data) | |||||||||
| Toxicity | rat,LD50,oral,3710mg/kg (3710mg/kg),"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1055, 1986. | |||||||||
| NFPA 704 |
|
4-Nitrotoluene-2-sulfonic Acid price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | N0277 | 4-Nitrotoluene-2-sulfonic Acid Hydrate >95.0%(T) | 121-03-9 | 25g | $58 | 2026-03-19 | Buy |
| TCI Chemical | N0277 | 4-Nitrotoluene-2-sulfonic Acid Hydrate >95.0%(T) | 121-03-9 | 500g | $315 | 2026-03-19 | Buy |
| TRC | N572320 | 5-Nitro-o-toluenesulfonicAcid | 121-03-9 | 10g | $180 | 2021-12-16 | Buy |
| TRC | N572320 | 5-Nitro-o-toluenesulfonicAcid | 121-03-9 | 100g | $275 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 60760 | 5-Nitro-o-toluenesulfonicAcid | 121-03-9 | 10g | $675 | 2021-12-16 | Buy |
4-Nitrotoluene-2-sulfonic Acid Chemical Properties,Uses,Production
Chemical Properties
Plate-like crystals (recrystallized from water). Soluble in ethanol, ether, and chloroform.
Uses
5-Nitro-o-toluenesulfonic Acid is a precursor to 4,4''-dinitrostilbene-2,2''-disulfonic acid in fluorescent whitener.
Definition
ChEBI: The arenesulfonic acid that is toluene-2-sulfonic acid bearing a nitro substituent at C-4.
Production Methods
4-Nitrotoluene is sulfonated with 25 % oleum at 60 ℃ and worked up to give a solution of the sodium salt of 2-Methyl-5-nitrobenzenesulfonic acid.
Application
4-Nitrotoluene-2-sulfonic acid is an essential intermediate for producing fluorescent whitening agents, thousands of tons of which are manufactured annually. It is used principally as starting material for the production of 4,4'-dinitrostilbene-2,2'-disulfonic acid, which in turn is used for the manufacture of a host of fluorescent whitening agents based on cyanuric chloride of the 4,4'-bis([1,3,5-triazin-2-yl]amino)-stilbene-2,2'-disulfonic acid type. Further substantial amounts of 4-nitrotoluene-2-sulfonic acid are required to synthesize fluorescent whitening agents with other basic structures and of various dyes.
Flammability and Explosibility
Non flammable
4-Nitrotoluene-2-sulfonic Acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xin Cheng Yue Chemical Co.,Ltd | +86-021-57806787 +86-17701820076 | wuziwei@xinyuefirm.com | China | 31 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Dalian Richfortune Chemicals Co., Ltd | +86-86-411-84820922 +86-8613904096939 | sales@richfortunechem.com | China | 305 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from 4-Nitrotoluene-2-sulfonic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 2-Methyl-5-nitrobenzenesulfonic acid
121-03-9
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-09-29 | 4-nitrotoluene-2-sulphonic acid
121-03-9
|
US $0.00-0.00 / kg | 1000kg | 78% | 10000ton | Shanghai Xin Cheng Yue Chemical Co.,Ltd | |
 |
2025-09-25 | 2-Methyl-5-nitrobenzenesulfonic acid
121-03-9
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 2-Methyl-5-nitrobenzenesulfonic acid
121-03-9
- US $1.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-nitrotoluene-2-sulphonic acid
121-03-9
- US $0.00-0.00 / kg
- 78%
- Shanghai Xin Cheng Yue Chemical Co.,Ltd
-
- 2-Methyl-5-nitrobenzenesulfonic acid
121-03-9
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
