(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
![(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Structure](CAS/GIF/64285-06-9.gif)
- CAS No.
- 64285-06-9
- Chemical Name:
- (+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE
- Synonyms
- Antx-a;anatoxini;Anatoxin 1;Brn 5477454;(1r)-ethanon;(-)-Anatoxin;(+)-Anatoxin-a;(+/-)-ANATOXIN A;(+/-)-ANATOXIN A FUMERATE;(+/-)-ANATOXIN A FUMARATE
- CBNumber:
- CB5154476
- Molecular Formula:
- C10H15NO
- Molecular Weight:
- 165.23
- MDL Number:
- MFCD09701958
- MOL File:
- 64285-06-9.mol
| alpha | D25 +39.8° |
|---|---|
| Boiling point | 293.09°C (rough estimate) |
| Density | 1.0203 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Desiccate at +4°C |
| pka | 9.4(at 25℃) |
| form | White solid. |
| color | Oil |
| EWG's Food Scores | 1 |
| FDA UNII | 80023A73NK |
| EPA Substance Registry System | Ethanone, 1-(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl- (64285-06-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361-H302+H312+H332 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
| Toxicity | LD50 i.p. in mice: 200 mg/kg (Carmichael) |
(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE price More Price(1)
(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Chemical Properties,Uses,Production
Acute toxicity
Intraperitoneal-mouse LDL0: 0.25 mg/kg
Occurrence
An oily alkaloid, anatoxin-a has been isolated from Anabaena jfos-aquae.
Uses
(+)-Anatoxin-a is a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and New Zealand. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis.
Synthesis Reference(s)
Journal of the American Chemical Society, 106, p. 4539, 1984 DOI: 10.1021/ja00328a040
Biological Activity
A potent nicotinic agonist (K i values are 1.25 and 1840 nM for α 4 β 2 and α 7 nicotinic receptors respectively). Stimulates [ 3 H]-dopamine release from rat striatal synaptosomes (EC 50 = 136 nM).
Safety Profile
Poison by intraperitoneal route.An experimental teratogen. When heated todecomposition it emits toxic fumes of NOx.
(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-2-ACETYL-9-AZA BICYCLO[4.2.1]NON-2-ENE FUMARATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Ascent Scientific | 4401179829988 | customerservice@ascentscientific.co.uk | United Kingdom | 279 | 60 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 9946 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 40036 | 58 |
| Naturewill Biotechnology Co., Ltd. | 18113192475 18113192475 | 3157321941@qq.com | China | 5000 | 58 |