ChemicalBook >> CAS DataBase List >>2,6-DIMETHOXYANILINE

2,6-DIMETHOXYANILINE

CAS No.
2734-70-5
Chemical Name:
2,6-DIMETHOXYANILINE
Synonyms
2,6-dimethoxybenzenamine;NSC 43758;BUTTPARK 33\04-69;2,6-DIMETHOXYANILINE;2,6-Dimethoxyaniline >2,6-Dimethoxyaniline 98%;2,6-Dimethoxyaniline, 97%;2,6-Dimethoxy-phenylamine;2,6-Dimethoxyaniline ,98%;BenzenaMine, 2,6-diMethoxy-
CBNumber:
CB5164510
Molecular Formula:
C8H11NO2
Molecular Weight:
153.18
MDL Number:
MFCD00053934
MOL File:
2734-70-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45

2,6-DIMETHOXYANILINE Properties

Melting point 71-74
Boiling point 254℃
Density 1.096
refractive index 1.4770 (estimate)
Flash point 116℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form powder to crystal
pka 4.48±0.10(Predicted)
color White to Gray to Brown
Water Solubility Slightly soluble in water.
InChI InChI=1S/C8H11NO2/c1-10-6-4-3-5-7(11-2)8(6)9/h3-5H,9H2,1-2H3
InChIKey HQBJSEKQNRSDAZ-UHFFFAOYSA-N
SMILES C1(N)=C(OC)C=CC=C1OC
CAS DataBase Reference 2734-70-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS06,GHS08
Signal word  Warning
Hazard statements  H311-H332-H373-H302-H315-H319
Precautionary statements  P280h-P302+P352-P309-P310-P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501
Hazard Codes  Xi,T
Risk Statements  20/21/22-36/37/38-36-33
Safety Statements  26-36/37/39-36/37-28
RIDADR  UN2811
Hazard Note  Toxic/Irritant
TSCA  N
HazardClass  6.1
PackingGroup  III
HS Code  29214200
NFPA 704
1
3 0

2,6-DIMETHOXYANILINE price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D4480 2,6-Dimethoxyaniline >98.0%(GC) 2734-70-5 1g $52 2025-07-31 Buy
TCI Chemical D4480 2,6-Dimethoxyaniline >98.0%(GC) 2734-70-5 5g $203 2025-07-31 Buy
Alfa Aesar H27139 2,6-Dimethoxyaniline, 97% 2734-70-5 1g $83.65 2025-07-31 Buy
Alfa Aesar H27139 2,6-Dimethoxyaniline, 97% 2734-70-5 5g $268.65 2025-07-31 Buy
TRC D451870 2,6-Dimethoxyaniline 2734-70-5 100mg $45 2021-12-16 Buy
Product number Packaging Price Buy
D4480 1g $52 Buy
D4480 5g $203 Buy
H27139 1g $83.65 Buy
H27139 5g $268.65 Buy
D451870 100mg $45 Buy

2,6-DIMETHOXYANILINE Chemical Properties,Uses,Production

Chemical Properties

Off-white solid

Uses

2,6-Dimethylaniline degradation by Fenton process has been studied in depth for the purpose of learning more about the reactions involved in the oxidation of 2,6-dimethylaniline under various reaction conditions. Using a previously developed gas chromatographic-mass spectrometric assay, hemoglobin adducts of 2,6-dimethylaniline were detected covalently bound to rat hemoglobin after administration of either 2,6-dimethylaniline or lidocaine.

Synthesis

Benzamide, N-hydroxy-2,6-dimethoxy-

51410-99-2

2,6-DIMETHOXYANILINE

2734-70-5

N-hydroxy-2,6-dimethoxybenzamide (1a) (0.237 g, 1.2 mmol) was used as a raw material and it was mixed with K2CO3 (0.166 g, 1.2 mmol) and DMSO (0.5 mL). Acetic anhydride (1.1 mL, 0.012 mmol) was added to the mixture and the reaction system was heated to 50°C. After stirring the reaction at this temperature for 10 min, the reaction mixture was cooled to 0°C and subsequently treated with 2M HCl (~2 mL). After the mixture was transformed into a clarified solution, it was neutralized by the addition of 2M NaOH (ca. 2 mL) and subsequently extracted with ether (Et2O, 15 mL x 3). The organic layers were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ether, 1:1) to afford the target product 2,6-dimethoxyaniline (2a) (0.171 g, 93% yield) as a white crystalline solid.

References

[1] Chemical Communications, 2009, # 17, p. 2281 - 2283
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 38, p. 9046 - 9054
[3] Tetrahedron Letters, 2015, vol. 56, # 5, p. 710 - 712

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View Lastest Price from 2,6-DIMETHOXYANILINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6-DIMETHOXYANILINE pictures 2025-07-07 2,6-DIMETHOXYANILINE
2734-70-5
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
2,6-DIMETHOXYANILINE pictures 2025-06-24 2,6-DIMETHOXYANILINE
2734-70-5
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2,6-DIMETHOXYANILINE  pictures 2022-08-04 2,6-DIMETHOXYANILINE
2734-70-5
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2,6-DIMETHOXYANILINE BUTTPARK 33\04-69 2,6-Dimethoxyaniline 98% 2,6-Dimethoxyaniline ,98% 2,6-Dimethoxy-phenylamine NSC 43758 BenzenaMine, 2,6-diMethoxy- 2,6-Dimethoxyaniline > 2,6-DIMETHOXYANILINE ISO 9001:2015 REACH 2,6-dimethoxybenzenamine 2,6-Dimethoxyaniline, 97% 2734-70-5 Anilines, Aromatic Amines and Nitro Compounds