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CARUMONAM

CARUMONAM
CARUMONAM structure
CAS No.
87638-04-8
Chemical Name:
CARUMONAM
Synonyms
AMA 1080;CARUMONAM;Ro 17-2301;CarlliIIonaln;CARUMONAM USP/EP/BP;Ro-17-2301:A-masulin;Antibiotic Ro 17-2301;(2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid;[[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid;[[[(Z)-2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3-yl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
CBNumber:
CB5165269
Molecular Formula:
C12H14N6O10S2
Formula Weight:
466.4
MOL File:
87638-04-8.mol

CARUMONAM Properties

alpha 
D26 -45° (c = 1 in DMSO)
Density 
2.13±0.1 g/cm3(Predicted)
pka
-0.43±0.60(Predicted)
FDA UNII
486890PI06

CARUMONAM Chemical Properties,Uses,Production

Description

Canunonam is an injectable antibiotic, the second monobactam ever developed (the first being Squibb’s aztreonam). It is highly active against Gram negative bacteria, particularly pseudomom, and is reportedly effective in the treatment of pneumonia, cystitis, peritonitis and secondary infections.

Originator

Takeda (Japan)

Definition

ChEBI: An N-sulfonated monobactam antibiotic.

brand name

Amasulin

Antimicrobial activity

A synthetic monobactam with activity against common pathogenic organisms similar to that of aztreonam. It is resistant to hydrolysis by the common plasmid and chromosomal β-lactamases, but it can be hydrolyzed by ESBLs.
It is administered intravenously, achieving a concentration of c. 78 mg/L after a 20-min infusion of 1 g. The plasma halflife is 1.7 h and the plasma protein binding 18–28%. Carumonam is almost entirely eliminated in the glomerular filtrate, probenecid having no effect on excretion; 96% of labeled compound is found in the urine, with 3% in the feces. Between 68% and 91% of the dose appears in the urine within 24 h.
Side effects and clinical use are similar to those of aztreonam.

CARUMONAM Preparation Products And Raw materials

Raw materials

Preparation Products


CARUMONAM Suppliers

Global( 31)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29865 58
Shaanxi Dideu Medichem Co. Ltd
13772537765
029-88380327 1010@dideu.com CHINA 3993 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17607 58
Shaanxi Dideu Medichem Co. Ltd
18192503167 +86-29-89586680
+86-29-88380327 1005@dideu.com CHINA 9937 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 29986 58
AFINE CHEMICALS LIMITED
008657185134551
008657185134895 info@afinechem.com CHINA 15559 58
BOC Sciences
16314854226
inquiry@bocsci.com United States 19674 58
Chembest Research Laboratories Limited 021-20908456-
021-58180499 sales@BioChemBest.com China 5948 61
Beijing HuaMeiHuLiBiological Chemical 010-56205725
010-65763397 waley188@sohu.com China 12341 58
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810-
025-57019371 sales@sunlidabio.com;sales@sunlidabio.com China 3756 55

View Lastest Price from CARUMONAM manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-20 CaruMonaM
87638-04-8
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
2021-06-22 CARUMONAM USP/EP/BP
87638-04-8
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
2019-12-26 CARUMONAM
87638-04-8
US $1.00 / g 1g ≥98% g/kg/Ton Career Henan Chemical Co

87638-04-8(CARUMONAM)Related Search:


  • CARUMONAM
  • Acetic acid, [[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
  • Acetic acid, [[[2-[[2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-, [2S-[2α,3α(Z)]]-
  • AMA 1080
  • Antibiotic Ro 17-2301
  • Ro 17-2301
  • (2S)-2α-(Carbamoyloxymethyl)-3α-[[(Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-4-oxoazetidine-1-sulfonic acid
  • [[[(Z)-2-[[(2S)-2α-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3α-yl]amino]-1-(2-aminothiazol-4-yl)-2-oxoethylidene]amino]oxy]acetic acid
  • [[[(Z)-2-[[(2S,3S)-2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfoazetidin-3-yl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
  • [2S-[2α,3α(Z)]]-[[[2-[[2-[[(Aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]acetic acid
  • CarlliIIonaln
  • Ro-17-2301:A-masulin
  • Acetic acid, 2-[[(Z)-[2-[[(2S,3S)-2-[[(aminocarbonyl)oxy]methyl]-4-oxo-1-sulfo-3-azetidinyl]amino]-1-(2-amino-4-thiazolyl)-2-oxoethylidene]amino]oxy]-
  • CARUMONAM USP/EP/BP
  • 87638-04-8
  • C12H14N6O10S2
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