Succinic anhydride
- CAS No.
- 108-30-5
- Chemical Name:
- Succinic anhydride
- Synonyms
- SAN;succinic;SAA;DIHYDRO-2,5-FURANDIONE;SUCCINIC ACID ANHYDRIDE;SAA1;Dihydro-furan-2,5-dione;BUTANEDIOIC ANHYDRIDE;Bernsteinsaure-anhydrid;Tetrahydrofuran-2,5-dione
- CBNumber:
- CB5166246
- Molecular Formula:
- C4H4O3
- Molecular Weight:
- 100.07
- MDL Number:
- MFCD00005525
- MOL File:
- 108-30-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Succinic anhydride for synthesis | 8.00683 | 100g | $41.1 |
| Succinic anhydride for synthesis | 8.00683 | 500g | $57 |
| Succinic anhydride for synthesis | 8.00683 | 1kg | $82.9 |
| Human Serum Amyloid A ELISA Kit for serum, plasma, cell culture supernatant and urine | RAB0420 | 1 kit | $569 |
| Succinic anhydride for synthesis | 8.00683 | 50kg | $1740 |
| More product size | |||
| Melting point | 118-120 °C (lit.) |
|---|---|
| Boiling point | 261 °C (lit.) |
| Density | 1,572 g/cm3 |
| bulk density | 550-600kg/m3 |
| vapor density | 3.5 (vs air) |
| vapor pressure | 1 mm Hg ( 92 °C) |
| refractive index | 1.4688 (estimate) |
| Flash point | 157°C |
| storage temp. | Store below +30°C. |
| solubility | 62.9g/l Hydrolysis |
| form | Solid |
| pka | 4.67[at 20 ℃] |
| color | White to Off-White |
| Specific Gravity | 1.2340 (20℃) |
| PH | 2.7 (10g/l, H2O) |
| Odor | Odorless |
| Water Solubility | <0.1 g/100 mL at 21 ºC (decomposes) |
| Sensitive | Moisture Sensitive |
| Merck | 14,8870 |
| BRN | 108441 |
| Stability | Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture. |
| InChIKey | RINCXYDBBGOEEQ-UHFFFAOYSA-N |
| LogP | 2.44 at 40℃ |
| Toxicology and Carcinogenesis | Toxicology and Carcinogenesis Studies of Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies) |
| Substances Added to Food (formerly EAFUS) | SUCCINIC ANHYDRIDE |
| CAS DataBase Reference | 108-30-5(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | 6RF4O17Z8J |
| IARC | 3 (Vol. 15, Sup 7) 1987 |
| NIST Chemistry Reference | 2,5-Furandione, dihydro-(108-30-5) |
| EPA Substance Registry System | Succinic anhydride (108-30-5) |
| UNSPSC Code | 41116158 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H290 | |||||||||
| Precautionary statements | P234-P390 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37-22 | |||||||||
| Safety Statements | 25-46 | |||||||||
| RIDADR | UN 3261 8 / PGII | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | WN0875000 | |||||||||
| F | 21 | |||||||||
| Autoignition Temperature | 480 °C | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| HS Code | 29171990 | |||||||||
| Hazardous Substances Data | 108-30-5(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: 1510 mg/kg | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Succinic anhydride price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 100g | $41.1 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 500g | $57 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 1kg | $82.9 | 2025-07-31 | Buy |
| Sigma-Aldrich | RAB0420 | Human Serum Amyloid A ELISA Kit for serum, plasma, cell culture supernatant and urine | 1 kit | $569 | 2025-07-31 | Buy | |
| Sigma-Aldrich | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 50kg | $1740 | 2025-07-31 | Buy |
Succinic anhydride Chemical Properties,Uses,Production
Description
Succinic anhydride, also called di hydro - 2,5- furandione , is an organic compound with the molecular formula C4H4O3.This colorless solid is the acid anhydride of succinic acid.
Chemical Properties
fine white crystalline solid
Chemical Properties
Succinic anhydride is an odourless, colourless needle-like or white crystalline solid natural product. Molecular formula C4H4O3, molecular weight 100.07 g/mol, relative density 1.503, melting point 237 °F. 239 °F at 5 mmHg, 239 °F at 198 °F and 1 mmHg. Soluble in chloroform, carbon tetrachloride, and ethanol; very slightly soluble in ether and water (insoluble in water). Moderately toxic and irritating, emits pungent and irritating fumes when heated to decomposition.
Uses
Succinic Anhydride is an acidulant that hydrolyzes very slowly to succinic acid in water. it has thermal stability and a low melting point of 118°c which permits it to be used in products at compara- tively low temperatures. it is used as a leavening acidulant for bak- ing powder.
Uses
It was used in the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.It was also used in preparing functionalized oxide surfaces on a chip.
Uses
Succinic Anhydride is a useful compound in the paper manufacturing process.
Preparation
A solution of succinic acid (500 mg, 42 mmol) and triethylamine (1.23 mL, 42 mmol) in anhydrous THF (120 mL) was allowed to react with triphosgene (42 mg, 7.0 mmol) at ice-water temperature for 10 min. The reaction mixture was subsequently stirred for a further 15 min at room temperature. The solution was then filtered, and the filtrate was concentrated to dryness. The residue was crystallized from ethyl acetate to afford the desired product as white crystals (370 mg, 85%).
Production Methods
The compound is produced from succinic anhydride and hydrogen peroxide . This material must be stabilized by using a dehydrating agent such as disodium sulfate or magnesium sulfate.
Application
Alkyl succinic anhydride (ASA) is used as a sizing agent or wet strength additive in paper production.
Definition
ChEBI: Succinic anhydride is a cyclic dicarboxylic anhydride and a tetrahydrofurandione. It is functionally related to a succinic acid.
Synthesis Reference(s)
Synthetic Communications, 23, p. 419, 1993 DOI: 10.1080/00397919308009796
General Description
Succinic anhydride is a cyclic anhydride of succinic acid with a five-membered ring. It is widely used in the manufacture of polymeric materials, pharmaceuticals, agrochemicals, dyes, surface-active agents, and organic flame-retardant materials. It also finds application as a cross-linking agent in ion-exchange membranes and a curing agent for epoxy resins.
General Description
Colorless needles or white crystalline solid. Melting point 237°F. Sublimes at 239°F at 5 mm Hg pressure; and at 198°F and 1 mm Hg pressure. Moderately toxic and an irritant.
Air & Water Reactions
Reacts slowly with water. Insoluble in water.
Reactivity Profile
Succinic anhydride reacts exothermically with water. Reactions are usually slow, but might become violent if local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Fire Hazard
Flash point data for Succinic anhydride are not available, however, Succinic anhydride is probably combustible.
Flammability and Explosibility
Not classified
Materials Uses
Succinic anhydride can be used:
(1) In the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.
(2) In preparing functionalized oxide surfaces on a chip.
(3) As a starting material to synthesize polyesters in presence of a metal triflate as a catalyst.
(4) As a cross-linking agent to enhance the mechanicalproperties and antimicrobial activities of zein films.
Safety Profile
Experimental teratogenic effects. Moderately toxic by ingestion. A severe eye irritant. Mutation data reported. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also ANHYDRIDES.
Purification Methods
Crystallise the anhydride from redistilled acetic anhydride or CHCl3, then filter, wash with diethyl ether and dry it in a vacuum. [Beilstein 17 H 606, 17 V 6.]
Succinic anhydride Preparation Products And Raw materials
Raw materials
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Preparation Products
1of6
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Mainchem Co., Ltd. | -- | sarah@mainchem.com | China | 6547 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Langfang Hawk Techology & Development Co, Ltd. | +8618631652130 | info@hawk-chinachem.com | China | 23 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Puyang Huicheng Electronic Materials Co., Ltd. | +86-0393-+86-0393-8910800 +8615839383373 | info@huichengchem.com | China | 529 | 58 |
| Xinxiang Hongqi District Houyuan Trading Co.,Ltd | +86-0373-3695376 +86-13937349994 | HYJM@houyuanjm.com | China | 299 | 58 |
| Handan Huajun chemicals Co.,Ltd | +86-0310-8166573 +8618630058311 | sales@huajunchem.com | China | 36 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8768 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3994 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5249 | 58 |
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View Lastest Price from Succinic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-11 | Succinic anhydride
108-30-5
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-12-11 | Succinic anhydride
108-30-5
|
US $10.00 / kg | 1kg | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-11 | Succinic anhydride
108-30-5
|
US $2.00 / kg | 1kg | 99.9% min | 5000mt | Handan Huajun chemicals Co.,Ltd |
-
- Succinic anhydride
108-30-5
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Succinic anhydride
108-30-5
- US $10.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Succinic anhydride
108-30-5
- US $2.00 / kg
- 99.9% min
- Handan Huajun chemicals Co.,Ltd
