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(-)-LEUKOTRIENE A4 METHYL ESTER

(-)-LEUKOTRIENE A4 METHYL ESTER Structure
(-)-LEUKOTRIENE A4 METHYL ESTER structure
CAS No.
73466-12-3
Chemical Name:
(-)-LEUKOTRIENE A4 METHYL ESTER
Synonyms
(-)-leukotriene A4;PWXYNAKNLZUYAL-WAQVJNLQSA-N;LEUKOTRIENE A4 METHYL ESTER;(-)-LEUKOTRIENE A4 METHYL ESTER;LTA4 (Leukotriene A4 methyl ester);5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER;LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE);2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)-
CBNumber:
CB5184743
Molecular Formula:
C21H32O3
Molecular Weight:
332.48
MDL Number:
MFCD00065847
MOL File:
73466-12-3.mol
Last updated:2023-06-28 08:28:16
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(-)-LEUKOTRIENE A4 METHYL ESTER Properties

storage temp. −20°C
solubility Acetone: >50 mg/ml; DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: insoluble and unstable.
form triethylamine:hexane solution
FDA UNII 7Y7MPZ6563

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H225-H315-H319-H361-H336-H373-H304-H411
Precautionary statements  P201-P202-P210-P240-P241-P242-P243-P260-P264-P271-P273-P280-P301+P310-P321-P331-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P314-P362+P364-P332+P313-P337+P313-P370+P378-P391-P403+P233-P403+P235-P405-P501
Hazard Codes  F,Xn,N
Risk Statements  11-36/37/38-48/20-51/53-62-65-67
Safety Statements  9-16-29-33-36/37-61-62
RIDADR  UN 1208 3/PG 2
WGK Germany  2
NFPA 704
3
2 0

(-)-LEUKOTRIENE A4 METHYL ESTER price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 73466-12-3 25μg $144 2024-03-01 Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 73466-12-3 50μg $274 2024-03-01 Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 73466-12-3 100μg $519 2024-03-01 Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 73466-12-3 500μg $1579 2023-06-20 Buy
Usbiological 366268 Leukotriene A4 73466-12-3 96Tests $938 2021-12-16 Buy
Product number Packaging Price Buy
20010 25μg $144 Buy
20010 50μg $274 Buy
20010 100μg $519 Buy
20010 500μg $1579 Buy
366268 96Tests $938 Buy

(-)-LEUKOTRIENE A4 METHYL ESTER Chemical Properties,Uses,Production

Description

Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

Uses

LTA4 (Leukotriene A4 methyl ester) is an unstable intermediate in the biosynthesis of LTB4 and LTC4.

(-)-LEUKOTRIENE A4 METHYL ESTER synthesis

73958-00-6
73958-09-5
73466-12-3
Synthesis of (-)-LEUKOTRIENE A4 METHYL ESTER from METHYL-(5S,6S)-EPOXY-11-OXO-(7E,9E)-UNDECADIENOATE and Phosphorane, (3Z)-3-nonen-1-ylidenetriphenyl-

(-)-LEUKOTRIENE A4 METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-LEUKOTRIENE A4 METHYL ESTER Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Alfa Chemistry 		+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3004 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Supplier Advantage
Alfa Chemistry 		58
Aladdin Scientific 		58
Alfa Chemistry 60
Shanghai EFE Biological Technology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
amyjetsci 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58

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(-)-LEUKOTRIENE A4 METHYL ESTER LEUKOTRIENE A4 METHYL ESTER (-)-leukotriene A4 LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE) LTA4 (Leukotriene A4 methyl ester) 5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER PWXYNAKNLZUYAL-WAQVJNLQSA-N 2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)- 73466-12-3 Biochemicals and Reagents BioChemical Unsaturated fatty acids and derivatives Esters Fatty Acids Methyl Esters Lipids