ChemicalBook >> CAS DataBase List >>Rimeporide
Rimeporide
- CAS No.
- 187870-78-6
- Chemical Name:
- Rimeporide
- Synonyms
- EMD-87580;Rimeporide;Rimeporide (EMD-87580);EMD-87580 >=98% (HPLC);N-carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide;N-(diaminomethylidene)-2-methyl-4,5-bis(methylsulfonyl)benzamide;Benzamide, N-(aminoiminomethyl)-2-methyl-4,5-bis(methylsulfonyl)-;Inhibitor,EMD87580,Sodium-hydrogen Exchanger,Sodium/hydrogen Exchanger,Rimeporide,inhibit,EMD 87580,Na+/H+ Exchanger (NHE)
- CBNumber:
- CB51856069
- Molecular Formula:
- C11H15N3O5S2
- Molecular Weight:
- 333.38
- MDL Number:
- MOL File:
- 187870-78-6.mol
- MSDS File:
- SDS
Last updated:2023-09-04 16:42:00
| Density | 1.55±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | -20°C |
| solubility | DMSO : 20 mg/mL (59.99 mM) |
| form | powder |
| pka | 10.50±0.46(Predicted) |
| color | white to beige |
| FDA UNII | QH6B4V5743 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
Rimeporide price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1828 | EMD-87580 ≥98% (HPLC) | 187870-78-6 | 5mg | $144 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1828 | EMD-87580 ≥98% (HPLC) | 187870-78-6 | 25mg | $580 | 2024-03-01 | Buy |
| ChemScene | CS-0015014 | Rimeporide 98.77% | 187870-78-6 | 1mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-0015014 | Rimeporide 98.77% | 187870-78-6 | 5mg | $390 | 2021-12-16 | Buy |
| Ambeed | A1147312 | N-Carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide 99% | 187870-78-6 | 5mg | $415 | 2021-12-16 | Buy |
Rimeporide Chemical Properties,Uses,Production
Uses
EMD-87580 has been used as a selective and potent sodium-hydrogen antiporter 1 (NHE-1) inhibitor in cardiac ventricular myocytes to test its effect on the hypertrophic response.
Biochem/physiol Actions
EMD-87580 is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. EMD-87580 has shown cardioprotective effects, and has been investigated as a possible treatment for Duchenne′s muscular dystrophy.
Rimeporide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 26)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3444 | 55 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22346 | 58 |
Rimeporide
N-carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide
N-(diaminomethylidene)-2-methyl-4,5-bis(methylsulfonyl)benzamide
EMD-87580
Benzamide, N-(aminoiminomethyl)-2-methyl-4,5-bis(methylsulfonyl)-
EMD-87580 >=98% (HPLC)
Inhibitor,EMD87580,Sodium-hydrogen Exchanger,Sodium/hydrogen Exchanger,Rimeporide,inhibit,EMD 87580,Na+/H+ Exchanger (NHE)
Rimeporide (EMD-87580)
187870-78-6
C11H15N3O5S2