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Ethyl (R)-(-)-4-cyano-3-hydroxybutyate

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate structure
CAS No.
141942-85-0
Chemical Name:
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
Synonyms
ATS-5;RETINCIC ACID;Ethyl (R)-(−Ethyl (R)-(-)-4-cyan;(R)-Ethyl 4-cyano-3-;Ats-5(For Atorvastatin);Atorvastatin Impurity 127;)-4-cyano-3-hydroxybutyrate;(R)-4-cyano-3-hydroxybutyric;(R)-4-Cyano-3-hydroxy butanoate
CBNumber:
CB5188978
Molecular Formula:
C7H11NO3
Formula Weight:
157.17
MOL File:
141942-85-0.mol

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Properties

alpha 
-5 º (neat)
Boiling point:
270 °C(lit.)
Density 
1.114 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.448(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
pka
13.03±0.20(Predicted)
form 
Liquid
Specific Gravity
1.114
color 
Colorless to yellow
optical activity
[α]25/D 5°, neat
BRN 
5328715
InChIKey
LOQFROBMBSKWQY-ZCFIWIBFSA-N
CAS DataBase Reference
141942-85-0(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  1
HS Code  29269090

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 479772 Ethyl (R)-(?)-4-cyano-3-hydroxybutyrate 95% 141942-85-0 5g $54.9 2021-03-22 Buy
TCI Chemical C1474 Ethyl (R)-(-)-4-Cyano-3-hydroxybutyrate >97.0%(GC) 141942-85-0 1g $17 2021-03-22 Buy
TCI Chemical C1474 Ethyl (R)-(-)-4-Cyano-3-hydroxybutyrate >97.0%(GC) 141942-85-0 5g $47 2021-03-22 Buy
Alfa Aesar L19771 Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate, 98% 141942-85-0 5g $42.6 2021-03-22 Buy
Alfa Aesar L19771 Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate, 98% 141942-85-0 25g $136 2021-03-22 Buy

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Chemical Properties,Uses,Production

Chemical Properties

yellow liquid

Uses

Atorvastatin Intermediate

Uses

analgesic, antipyretic, and anti-inflammatory

Application

Hydroxyglutaryl coenzyme A (HMG-CoA) reductase inhibitors are a new class of lipid-lowering drugs, and they have a market share of more than 10 billion US dollars in the current pharmaceutical field. They can selectively inhibit the rate-limiting enzyme HMG-CoA reductase in cholesterol synthesis in the liver, reduce liver lipoprotein production, and increase the expression of low-density lipoprotein (LDL) cholesterol receptors, thereby reducing plasma cholesterol levels. They can also significantly reduce very low-density lipoprotein (VLDL) and triglycerides, and increase anti-atherosclerotic high-density protein (HDL), preventing atherosclerosis and coronary heart disease.
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate is an important intermediate for the synthesis of HMG-CoA reductase inhibitors. If it is used as a raw material, synthetic atorvastatin is mainly used for the treatment of hypercholesterolemia and mixed hyperlipidemia, coronary heart disease and stroke.

Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Preparation Products And Raw materials

Raw materials

Preparation Products


Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Suppliers

Global( 286)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21652 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22610 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8867 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 567 55
Zjartschem
+86-571-8723 8903 jocelynpan@zjarts.com
+86-571-87063838 jocelynpan@zjarts.com CHINA 997 58
Hebei Minshang Biotechnology Co., Ltd
+86-13582176207 +86-13582176207
cathy@hbminshang.cn CHINA 301 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30003 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135
sales@nbinno.com CHINA 925 58
Hehei Huanhao Biotechnology Co.,Ltd
+8618034552304 +86 19930599843
cindy@fenxiangtrade.com CHINA 575 58

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View Lastest Price from Ethyl (R)-(-)-4-cyano-3-hydroxybutyate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-12-11 (Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
141942-85-0
US $100.00 / KG 100IU 99% 10 Hebei Henghe Import and Export Trading Co. LTD
2018-08-16 Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
141942-85-0
US $11.00 / KG 1KG 99% 1000KG career henan chemical co
2018-03-30 Ethyl (R)-(-)-4-cyano-3-hydroxybutyrate[141942-85-0]
141942-85-0
US $10.00 / KG 10G 99% 10MT Hubei XinRunde Chemical Co., Ltd.

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