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2-(Trifluoromethyl)benzoyl chloride

2-(Trifluoromethyl)benzoyl chloride structure

CAS No.: 312-94-7

Chemical Name:: 2-(Trifluoromethyl)benzoyl chloride

Synonyms: alpha,alpha,alpha-Trifluoro-o-toluoyl chloride;à;OTF-BOC;TIMTEC-BB SBB006689;TrifluoroMethyl)benzoyl chlori;α,α,α-trifluoro-o-toluoyl chloride;à,à,à-trifluoro-o-toluoyl chloride;2-(TrifluoroMehtyl)benzoylcholride;2-(TRIFLUOROMETHYL)BENZOYL CHLORIDE;O-(TRIFLUOROMETHYL)BENZOYL CHLORIDE

CBNumber:: CB5193552

Molecular Formula:: C8H4ClF3O

Molecular Weight:: 208.57

MDL Number:: MFCD00000667

MOL File:: 312-94-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:28

Product description	Number	Pack Size	Price
2-(Trifluoromethyl)benzoyl chloride 99%	249483	25g	$271
2-(Trifluoromethyl)benzoyl Chloride >98.0%(GC)(T)	T1280	25g	$36
2-(Trifluoromethyl)benzoyl chloride	T791135	100g	$495
2-(Trifluoromethyl)benzoyl chloride	T791135	25g	$165
2-(Trifluoromethyl)benzoyl chloride 98%	PC7590	500g	$280
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2-(Trifluoromethyl)benzoyl chloride Properties

Melting point	-22 °C
Boiling point	84-85 °C16 mm Hg(lit.)
Density	1.416 g/mL at 25 °C(lit.)
vapor pressure	60.66Pa at 25℃
refractive index	n20/D 1.479(lit.)
Flash point	204 °F
storage temp.	Inert atmosphere,Room Temperature
form	Liquid
Specific Gravity	1.416
color	Clear pink or yellow
Water Solubility	decomposes
Sensitive	Lachrymatory
BRN	881040
InChI	1S/C8H4ClF3O/c9-7(13)5-3-1-2-4-6(5)8(10,11)12/h1-4H
InChIKey	MXIUWSYTQJLIKE-UHFFFAOYSA-N
SMILES	FC(F)(F)c1ccccc1C(Cl)=O
LogP	2.086
CAS DataBase Reference	312-94-7(CAS DataBase Reference)
FDA UNII	D01D0B64EQ
NIST Chemistry Reference	2-(Trifluoromethyl)benzoyl chloride(312-94-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H290-H318-H314

Precautionary statements

P309-P280-P305+P351+P338-P310-P234-P260-P264-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P405-P406-P501

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

34-37-29

Safety Statements

26-36/37/39-45-8

RIDADR

UN 3265 8/PG 2

WGK Germany

19-21

Hazard Note

Corrosive/Lachrymatory

HazardClass

PackingGroup

HS Code

29163990

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Skin Corr. 1B

Toxicity

skn-rbt 500 mg/24H MOD FCTXAV 13,681,75

Limited Quantities

1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	1
3		2
	W

2-(Trifluoromethyl)benzoyl chloride price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	249483	2-(Trifluoromethyl)benzoyl chloride 99%	312-94-7	25g	$271	2023-01-07	Buy
TCI Chemical	T1280	2-(Trifluoromethyl)benzoyl Chloride >98.0%(GC)(T)	312-94-7	25g	$36	2026-03-19	Buy
TRC	T791135	2-(Trifluoromethyl)benzoyl chloride	312-94-7	100g	$495	2021-12-16	Buy
TRC	T791135	2-(Trifluoromethyl)benzoyl chloride	312-94-7	25g	$165	2021-12-16	Buy
Apolloscientific	PC7590	2-(Trifluoromethyl)benzoyl chloride 98%	312-94-7	500g	$280	2021-12-16	Buy

Product number	Packaging	Price	Buy
249483	25g	$271	Buy
T1280	25g	$36	Buy
T791135	100g	$495	Buy
T791135	25g	$165	Buy
PC7590	500g	$280	Buy

2-(Trifluoromethyl)benzoyl chloride Chemical Properties,Uses,Production

Chemical Properties

colorlesstolightyellowliqui

Uses

2-(Trifluoromethyl)benzoyl chloride may be used in chemical synthesis.

Safety Profile

A skin irritant. When heated todecomposition it emits acrid smoke and irritating fumes.

Synthesis

433-97-6

312-94-7

Step 2: Synthesis of 2-(trifluoromethyl)benzoyl chloride Oxalyl chloride (36.72 mg, 0.29 mmol) was slowly added to a stirred solution of 2-(trifluoromethyl)benzoic acid (50 mg, 0.26 mmol) in dichloromethane (3 mL) followed by dropwise addition of N,N-dimethylformamide (DMF, 4 drops). The resulting reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and 2-(trifluoromethyl)benzoyl chloride (95.6 mg, 100% yield) was obtained quantitatively, which was used directly in the subsequent reaction without purification.

References

[1] Patent: US2010/160323, 2010, A1. Location in patent: Page/Page column 28
[2] Journal of the American Chemical Society, 1947, vol. 69, p. 2352
[3] Bulletin de la Societe Chimique de France, 1962, p. 587 - 593
[4] Journal of Medicinal Chemistry, 1982, vol. 25, # 2, p. 145 - 152
[5] Journal of Medicinal Chemistry, 1999, vol. 42, # 6, p. 981 - 991

2-(Trifluoromethyl)benzoyl chloride Preparation Products And Raw materials

Raw materials

2-(Trifluoromethyl)benzoic acid Oxalyl chloride Dichloromethane

Preparation Products

Flutolanil 2-(Trifluoromethyl)benzaldehyde Benzamide, N-hydroxy-2-(trifluoromethyl)-

2-(Trifluoromethyl)benzoyl chloride Suppliers

Global( 369)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13815	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29821	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10404	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Richest Group Ltd	58
Fuxin Pharmaceutical	58

View Lastest Price from 2-(Trifluoromethyl)benzoyl chloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-24	2-(Trifluoromethyl)benzoyl chloride 312-94-7	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-12-01	2-(Trifluoromethyl)benzoyl chloride 312-94-7	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-09-25	2-(Trifluoromethyl)benzoyl chloride 312-94-7	US $8.00-0.80 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

2-(Trifluoromethyl)benzoyl chloride
312-94-7
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-(Trifluoromethyl)benzoyl chloride
312-94-7
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-(Trifluoromethyl)benzoyl chloride
312-94-7
US $8.00-0.80 / KG
99%
Henan Fengda Chemical Co., Ltd

2-(Trifluoromethyl)benzoyl chloride Spectrum

2-(Trifluoromethyl)benzoyl chloride(312-94-7)MS 2-(Trifluoromethyl)benzoyl chloride(312-94-7)¹HNMR 2-(Trifluoromethyl)benzoyl chloride(312-94-7)IR1 2-(Trifluoromethyl)benzoyl chloride(312-94-7)Raman

312-94-7(2-(Trifluoromethyl)benzoyl chloride)Related Search:

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Benzene Benzoyl peroxide 2,4,6-Trimethylbenzoyl chloride

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Benzoyl chloride, 2-(trifluoromethyl)- TIMTEC-BB SBB006689 O-(TRIFLUOROMETHYL)BENZOYL CHLORIDE OTF-BOC o-Trifluoromethylbenzoyl Chloride 2-Trifluoromethylbenzoyl Chloride 2-(Trifluoromethyl)benzene-1-carbonyl chloride 2-(TRIFLUOROMETHYL)BENZOYL CHLORIDE à,à,à-trifluoro-o-toluoyl chloride α,α,α-trifluoro-o-toluoyl chloride 2-(Trifluoromethyl)benzoyl chloride 98% 2-(Trifluoromethyl)benzoylchloride98% 2-(Trifluoromethyl)benzoic acid chloride à O-(triflouromethyl)benzoyl Chloride 2-(Trifluoromethyl)benzoyl chloride,α,α,α-Trifluoro-o-toluoyl chloride 2-(TrifluoroMehtyl)benzoylcholride 2- threefluorine Methylbenzoyl chloride (2-Chlorocarbonyl)benzotrifluoride, alpha,alpha,alpha-Trifluoro-o-toluoyl chloride TrifluoroMethyl)benzoyl chlori alpha,alpha,alpha-Trifluoro-o-toluoyl chloride 2-(Trifluoromethyl)benzoyl chloride,97% 312-94-7 331-94-7 321-97-4 331-94-7 F3CC6H4COCl C8F3H4OCl Building Blocks Carbonyl Compounds ACID CHLORIDE Organic Building Blocks Acid Halides Aromatic Halides (substituted) Trifluoromethylbenzene serise