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Propyphenazone

Propyphenazone structure

CAS No.: 479-92-5

Chemical Name:: Propyphenazone

Synonyms: Budirol;Causyth;Larodon;Cibalgina;Isopyrine;Isopropchin;Isopropyrine;Propyphenazon;PROPYPHENAZONE;(-)-Asparagine

CBNumber:: CB5193729

Molecular Formula:: C14H18N2O

Molecular Weight:: 230.31

MDL Number:: MFCD00053368

MOL File:: 479-92-5.mol

MSDS File:: SDS

Last updated:2024-03-19 15:37:50

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Propyphenazone Properties

Melting point	102-105°C
Boiling point	372.3°C (rough estimate)
Density	1.0371 (rough estimate)
refractive index	1.5500 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
pka	1.46±0.65(Predicted)
color	White to Off-White
Water Solubility	743.6g/L(25.35 ºC)
Merck	14,7871
BRN	204533
Stability	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	479-92-5(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	OED8FV75PY
ATC code	N02BB04
NIST Chemistry Reference	Propyphenazone(479-92-5)
EPA Substance Registry System	3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- (479-92-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P501

Hazard Codes

Risk Statements

36/37/38-22

Safety Statements

26-36/37/39

WGK Germany

RTECS

CD2800000

HS Code

2933.39.9200

NFPA 704

	0
2		0

Propyphenazone price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR1389	Propyphenazone Pharmaceutical Secondary Standard; Certified Reference Material	479-92-5	1g	$97.5	2024-03-01	Buy
TCI Chemical	I0656	4-Isopropylantipyrine >98.0%(GC)	479-92-5	25g	$64	2024-03-01	Buy
Sigma-Aldrich	P3750000	Propyphenazone European Pharmacopoeia (EP) Reference Standard	479-92-5	p3750000	$153	2024-03-01	Buy
TRC	P838380	Propyphenazone	479-92-5	50g	$875	2021-12-16	Buy
American Custom Chemicals Corporation	API0007224	PROPYPHENAZONE 95.00%	479-92-5	25G	$950	2021-12-16	Buy

Product number	Packaging	Price	Buy
PHR1389	1g	$97.5	Buy
I0656	25g	$64	Buy
P3750000	p3750000	$153	Buy
P838380	50g	$875	Buy
API0007224	25G	$950	Buy

Propyphenazone Chemical Properties,Uses,Production

Description

This uncharacterized alkaloid has been described by Hartsen as occurring in Iso_x0002_pyrum thalictroides L. No chemical or physical characteristics are known.

Chemical Properties

solid

Uses

Analgesic; antipyretic; anti-inflammatory.

Definition

ChEBI: A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.

brand name

539 grippe-dragees;Amipylo-n;Balpiren;Baukal;Caffalgina;Camoplex;Cantacin;Cerebrol;Daturmed;Degripol;Dentocaps a;Dim-antos;Dolibral;Dolo-mineuron;Dysmalgin;Ejcopyrin;Epizon;Escomen;Estesina;Fd 8;Febral;Finigripp;Grippocaps;Heaven;Infantex;Influvit;Isopronazon;Kavapyret;Kuronde;Lysadestat;Mamaslu;Milneuron;Myo-europan;Neuramin;Neuridal;Neuro-spondryl;Nodiras;Noric;Otobacid;Pfeil;Reomin;Retamex;Rheumanol;Rhinivict;Sanalgin-p;Saridon neu;Saridone;Sedospin;Servalgin;Sonotryl;Spalt;Spongamed;Stona;Synpyrin;Vivcet;Wauco-sin;Wecontrin.

World Health Organization (WHO)

Propyphenazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1951 for the treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations. See also WHO comment for aminophenazone.

Clinical Use

Propyphenazone is a derivative of phenazone and has a similar analgesic and antipyretic action. It is used as a monocompound as well as in multi-ingredient preparations.

References

Hartsen., J. Chem. Soc., 511 (1873) Mirande., Compt. rend., 168,316 (1919)

Propyphenazone Preparation Products And Raw materials

Raw materials

Preparation Products

Propyphenazone Suppliers

Global( 231)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Casorganics US Corp	+17326109938	sales@casorganics.com	CHINA	174	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-18612256290	1056@dideu.com	China	3791	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29474	58

Supplier	Advantage
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Casorganics US Corp	58
Xiamen AmoyChem Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dideu Industries Group Limited	58

View Lastest Price from Propyphenazone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-03-06	Propyphenazone 479-92-5	US $1.90 / KG	1KG	99%	10 ton	Hebei Guanlang Biotechnology Co,.LTD
2021-10-30	Propyphenazone 479-92-5	US $0.00 / Kg/Drum	1KG	98%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2021-07-20	Propyphenazone 479-92-5	US $1.00-1.00 / KG	1g	99%	50tons	Shaanxi Dideu Medichem Co. Ltd

Propyphenazone
479-92-5
US $1.90 / KG
99%
Hebei Guanlang Biotechnology Co,.LTD

Propyphenazone
479-92-5
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Propyphenazone
479-92-5
US $1.00-1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

Propyphenazone Spectrum

Propyphenazone(479-92-5)MS Propyphenazone(479-92-5)¹HNMR Propyphenazone(479-92-5)¹³CNMR Propyphenazone(479-92-5)IR1 Propyphenazone(479-92-5)IR2

479-92-5(Propyphenazone)Related Search:

Poly(dimethylsiloxane) Dimethyl sulfoxide ETHANE Dimethyl fumarate Dimethyl ether

Chlorodimethylphenylsilane DIANTIPYRYLMETHANE 5-Chlorovaleric acid Pralmorelin Dimethyl carbonate

Diisopropyl ether Isoproterenol Diphenolic acid N,N-Dimethylformamide N,N-Dimethylaniline

Dimethyl sulfide Isoproturon Dimethyl sulfone

1of4

2,3-dimethyl-4-isopropyl-1-phenyl-3-pyrazolin-5-on 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- 3H-Pyrazol-3-one,1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- 3-Pyrazolin-5-one, 2,3-dimethyl-4-isopropyl-1-phenyl- 4-ISOPROPYL-2,3-DIMETHYL-1-PHENYL-5-PYRAZOLONE 2,3-Dimethyl-1-phenyl-4-isopropylpyrazolone 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazoline-5-on 4-ISO-PROPYL-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE(PROPYPHENAZONE) 3,3-Dimethyl-2-Methylene Norcamphone 1,5-Dimethyl-4-(1-methylethyl)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one 1,5-dimethyl-2-phenyl-4-propan-2-yl-pyrazol-3-one 1,5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one 4-isopropyl-1,5-dimethyl-2-phenyl-pyrazol-3-one PROPYLPHENAZONE ANTIBIOTICTPJ-B Propyphenazone (EDMF) 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3h-pyrazol-3-on 3-Pyrazolin-5-one, 4-isopropyl-2,3-dimethyl-1-phenyl- 4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one 4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one 4-Isopropyl-2,3-dimethyl-5-oxo-1-phenyl-3-pyrazoline 4-isopropyl-antipyrin 4-Isopropylphenazone Antipyrine, 4-isopropyl- Budirol Causyth Cibalgina Isopropchin Isopropylantipyrin Isopropyrine Isopyrine Larodon ISOPROPYLANTIPYRINE ISOPROPYLANTIPYRINUM 4-ISOPROPYLANTIPYRINE 4-ISOPROPYL-1,5-DIMETHYL-2-PHENYL-3-PYRAZOLONE PROPYPHENAZONE ISOPROPYLPHENAZONE 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-Pyrazol-3-one 1,2-dihydro-1,5-dimethyl-4-(isopropyl)-2-phenyl-pyrazol-3-one 1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one 1-phenyl-2,3-dimethyl-4-isopropyl-5-Pyrazolone 1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one 2,3-Dimethyl-4-isopropyl-1-phenyl-3H-pyrazolin-5-one Phentermine Solution, 100ppm 2-propyl-2H-phenazin-1-one Propyphenazone (4-Isopropylantipyrine) 4-Isopropylantipyrine> Propyphenazone CRS 4-isopropyl-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one Propyphenazone USP/EP/BP Propyphenazone, Pharma Isopropyl PhenazoneQ: What is Isopropyl Phenazone Q: What is the CAS Number of Isopropyl Phenazone Q: What is the storage condition of Isopropyl Phenazone (-)-Asparagine Propyphenazon Resveratrol Impurity 39（Oxyresveratrol 3'-O-β-D-glucopyranoside）