ChemicalBook >> CAS DataBase List >>Azosemide

Azosemide

Azosemide structure

CAS No.: 27589-33-9

Chemical Name:: Azosemide

Synonyms: Diart;Luret;SK-110;ple1053;azosemid;Diurapid;AZOSEMIDE;Azosemidum;AZOSEMIDE HPLC;Azosemide USP/EP/BP

CBNumber:: CB5200179

Molecular Formula:: C12H11ClN6O2S2

Molecular Weight:: 370.84

MDL Number:: MFCD00867321

MOL File:: 27589-33-9.mol

MSDS File:: SDS

Last updated:2023-10-09 22:51:44

Request For Quotation

Azosemide Properties

Melting point	218-221°
Boiling point	221°C (rough estimate)
Density	1.6843 (rough estimate)
refractive index	1.6100 (estimate)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	3.58±0.10(Predicted)
color	Crystals
CAS DataBase Reference	27589-33-9(CAS DataBase Reference)
FDA UNII	MR40VT1L8Z

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319-H227
Precautionary statements	P501-P261-P270-P210-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P235
Toxicity	LD50 orl-rat: 2545 mg/kg IYKEDH 18,666,87

Azosemide price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A965145	Azosemide	27589-33-9	10g	$845	2021-12-16	Buy
American Custom Chemicals Corporation	API0001575	AZOSEMIDE 95.00%	27589-33-9	100MG	$727.65	2021-12-16	Buy
AK Scientific	E592	Azosemide	27589-33-9	100mg	$298	2021-12-16	Buy
Biosynth Carbosynth	FA44032	Azosemide	27589-33-9	10mg	$40	2021-12-16	Buy
ChemScene	CS-0028137	Azosemide >98.0%	27589-33-9	10mg	$50	2021-12-16	Buy

Product number	Packaging	Price	Buy
A965145	10g	$845	Buy
API0001575	100MG	$727.65	Buy
E592	100mg	$298	Buy
FA44032	10mg	$40	Buy
CS-0028137	10mg	$50	Buy

Azosemide Chemical Properties,Uses,Production

Description

Azosemide is a high-ceiling diuretic similiar in structure and profile to furosemide, albeit somewhat less potent and less bioavailable. It is useful in the treatment of congestive heart failure and similar edematous conditions.

Originator

Boehringer Manheim (W. Germany)

Uses

Diuretic.

Uses

Azosemide is a high-ceiling diuretic agent. It is used in the treatment of edematous states and hypertension.

Definition

ChEBI: A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hyp rtension.

Manufacturing Process

The 4-chloro-5-sulfamoyl-2-thenylaminobenzonitrile used as starting material is obtained by the reaction of 4-chloro-2-fluoro-5-sutfamoyl-benzonitrile with thenylamine in anhydrous tetrahydrofuran.
Then the 5-(4'-chloro-5'-sulfamoyl-2'-thenylamino)phenyltetrazole (MP 218° to 221°C, yield 37% of theory) is obtained by the reaction of 4-chloro-5- sulfamoyl-2-thenylaminobenzonitrite (MP 170° to 174°C) with sodium azide and ammonium chloride,

brand name

LURET

Therapeutic Function

Diuretic

Safety Profile

Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Whenheated to decomposition it emits toxic fumes of Cl^-, SOx,and NOx.

Azosemide Preparation Products And Raw materials

Raw materials

Sodium azide Benzonitrile 2-thiophene

Preparation Products

Azosemide Suppliers

Global( 113)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Hubei XinRunde Chemical Co., Ltd.	+8615102730682	bruce@xrdchem.cn	CHINA	566	55
Tianjin Zhongxin Chemtech Co., Ltd.	+86-022-66880623 +8618622897568	sales@tjzxchem.com	China	559	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-18612256290	1056@dideu.com	China	3581	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hebei Binshare New Material Co. Ltd	+8618633865755	china01@hbbinshare.com	CHINA	969	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Hubei XinRunde Chemical Co., Ltd.	55
Tianjin Zhongxin Chemtech Co., Ltd.	58
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Binshare New Material Co. Ltd	58
TargetMol Chemicals Inc.	58

View Lastest Price from Azosemide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-24	Azosemide 27589-33-9	US $1.00 / g	1g	99%	300tons	Hebei Dangtong Import and export Co LTD
2024-02-22	Azosemide 27589-33-9	US $1.00 / g	1g	99%	10000kg	Hubei Langyou International Trading Co., Ltd
2023-10-09	Azosemide 27589-33-9	US $50.00 / kg	1kg	0.99	10000	Hebei Yanxi Chemical Co., Ltd.

Azosemide
27589-33-9
US $1.00 / g
99%
Hebei Dangtong Import and export Co LTD

Azosemide
27589-33-9
US $1.00 / g
99%
Hubei Langyou International Trading Co., Ltd

Azosemide
27589-33-9
US $50.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

Azosemide Spectrum

Azosemide(27589-33-9)¹HNMR

27589-33-9(Azosemide)Related Search:

Boc-D-Glutamine 2,3,5-Triphenyltetrazolium chloride 1H-Tetrazole-1-acetic acid N,N-Dimethylformamide Acrylamide

Tetrazole Polyacrylamide Sulfanilamide Nitrotetrazolium blue chloride 3-Aminobenzenesulfonamide

Acetamide Epichlorohydrin Polyamide Chlorantraniliprole Nicotinamide

Formamide Difluorochloromethane Chloroacetic acid

1of4

2-chloro-5-(1h-tetrazol-5-yl)-4-((2-thienylmethyl)amino)-benzenesulfonamid 2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenyl-sulfanilamid SK-110 2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide 2-chloro-5-(2H-tetrazol-5-yl)-4-(2-thienylmethylamino)benzenesulfonamide 2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide 2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenylsulfanilamide 5-(4’-chloro-5’-sulfamoyl-2’-thenylaminophenyl)-tetrazole azosemid ple1053 AZOSEMIDE 2-chloro-5-(1h-tetrazol-5-yl)-4-(2-thenylamino)benzenesulphonamide 2-CHLORO-5-(1H-TETRAZOL-5-YL)-4-((2-THIENYLMETHYL)AMINO)-BENZENESULFONAMIDE Azosemide(Chemical Name: 2-Chloro-5-(1h-Tertrazol-5-Yl)-N4-(2-Thenyl)) AZOSEMIDE HPLC Diart Diurapid Luret 2-Chloro-5-(1H-tetrazol-5-y1)-4-[(2-thienylmethyl)amino]benzenesulfona-Mide Azosemide USP/EP/BP Benzenesulfonamide, 2-chloro-5-(2H-tetrazol-5-yl)-4-[(2-thienylmethyl)amino]- Pharmaceutical Intermediate 98% Research Powder Azosemide Azosemidum Pharmaceutical Intermediate 98% Research Powder cas 27589-33-9 Azosemide Azosemide Solution, 100ppm Azosemide Solution, 1000ppm 2-Chloro-5-(1H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide 27589-33-9 C12H11CIN6O2S2 C12H11ClN6O2S2