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2,2'-Dithiodipyridine

2,2'-Dithiodipyridine Structure
2,2'-Dithiodipyridine structure
CAS No.
2127-03-9
Chemical Name:
2,2'-Dithiodipyridine
Synonyms
1,2-Di(pyridin-2-yl)disulfane;Aldrithiol;2-Aldrithiol;2-PDS;Dithiodipyridine;ALDRITHIOL-2;Dipyridyldisulfide;2-Pyridyl disulfide;2,2'-DIPYRIDYL DISULFIDE;1,2-Bis(2-pyridinyl) Disulfide
CBNumber:
CB5200205
Molecular Formula:
C10H8N2S2
Molecular Weight:
220.31
MDL Number:
MFCD00006287
MOL File:
2127-03-9.mol
MSDS File:
SDS
Last updated:2024-04-16 16:23:18
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2,2'-Dithiodipyridine Properties

Melting point 56-58 °C(lit.)
Boiling point 356.1±17.0 °C(Predicted)
Density 1.3078 (rough estimate)
refractive index 1.5500 (estimate)
Flash point 210 °C
storage temp. 2-8°C
solubility methanol: soluble50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow
pka 1.52±0.19(Predicted)
form powder
color Clear colorless to yellow to tan
Water Solubility 5 g/L (20 ºC)
BRN 154629
InChIKey HAXFWIACAGNFHA-UHFFFAOYSA-N
LogP 2.530 (est)
CAS DataBase Reference 2127-03-9(CAS DataBase Reference)
FDA UNII L6X912UPBU
NIST Chemistry Reference Pyridine, 2,2'-dithiobis-(2127-03-9)
EPA Substance Registry System Pyridine, 2,2'-dithiobis- (2127-03-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-37-20/22
Safety Statements  36/37/39-37/39-25-22-36-26
RIDADR  UN 3335
WGK Germany  3
F  10-23
Autoignition Temperature 340 °C
Hazard Note  Irritant
TSCA  Yes
HS Code  29333990
NFPA 704
0
2 0

2,2'-Dithiodipyridine price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 143049 Aldrithiol?-2 98% 2127-03-9 1g $67.2 2024-03-01 Buy
Sigma-Aldrich 8.41109 2,2′-Dipyridyl disulfide for synthesis 2127-03-9 5G $129 2024-03-01 Buy
Sigma-Aldrich 143049 Aldrithiol?-2 98% 2127-03-9 5g $128 2024-03-01 Buy
TCI Chemical D1114 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] >98.0%(GC)(T) 2127-03-9 5g $54 2024-03-01 Buy
TCI Chemical D1114 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] >98.0%(GC)(T) 2127-03-9 25g $162 2024-03-01 Buy
Product number Packaging Price Buy
143049 1g $67.2 Buy
8.41109 5G $129 Buy
143049 5g $128 Buy
D1114 5g $54 Buy
D1114 25g $162 Buy

2,2'-Dithiodipyridine Chemical Properties,Uses,Production

Chemical Properties

white to yellowish crystalline powder

Uses

Aldrithiol?-2 was used in the synthesis of adenosine-5′-phosphoimidazolide. It was employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.

Uses

2,2'-Dipyridyl disulfide is a useful reagent for determination of sulfhydryl groups, preparation of amino acid active esters and the thio esters of phosphoric acid. It acts as a peptide coupling reagent and as an oxidizing agent. It is also used for the activation of glycosides.

Uses

2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols and activating or protecting carboxylic acid with triphenylphosphine.

Definition

ChEBI: Aldrithiol is a member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols. It has a role as an oxidising agent. It is an organic disulfide and a member of pyridines.

General Description

Aldrithiol?-2 is a nucleocapsid zinc finger targeting compound and can abrogate the infectivity of human immunodeficiency virus type-1 virions. It is a thiol reagent.

Biochem/physiol Actions

2,2′-Dithiodipyridine mediates inter-unit disulfide cross-linking. It interacts with carbon nucleophiles to yield thiopyridyl derivatives.

Purification Methods

Recrystallise the disulfide H2O from *C6H6/pet ether (6:7), ligroin or *C6H6. The picrate has m 119o (from EtOH). [Walter et al. Justus Liebigs Ann Chem 695 7785 1966, Marckwald et al. Chem Ber 33 1556 1900, Brocklehurst & Little Biochem J 133 67,78 1973, Beilstein 21 III/IV 48.] It has been used as a 1mM solution in EtOH for the spectrophotometric estimation of thiols. Essentially the thiol displaces half the disulfide molecule liberating the 2-mercaptopyridine anion, thereby shifting the from 340nm (of the disulfide) to 268nm (of the anion) at pH 9, or 278nm in H2O. (Compare

2,2'-Dithiodipyridine synthesis

2637-34-5
2127-03-9
Synthesis of 2,2'-Dithiodipyridine from 2-Pyridinethione

2,2'-Dithiodipyridine Preparation Products And Raw materials

Raw materials

Pyrithione Bispyrithione

Preparation Products

Finasteride PYRIDINE-2-SULFONYL CHLORIDE Pyridine,2-(2-propen-1-ylthio)- 2-Pyridinesulfonamide(6CI,7CI,9CI) 2-Methylthiopyridine
2-(ethenesulfonyl)pyridine

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2,2'-Dithiodipyridine Suppliers

Global( 316)Suppliers
Supplier Tel Email Country ProdList Advantage
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Zjartschem 		+86-571-8723 8903 jocelynpan@zjarts.com jocelynpan@zjarts.com CHINA 993 58
Shanxi Naipu Import and Export Co.,Ltd 		+86-13734021967 +8613734021967 kaia@neputrading.com China 1011 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		+86 18953170293 sales@sdzschem.com China 2931 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Supplier Advantage
Chongqing Chemdad Co., Ltd
58
Hebei Yanxi Chemical Co., Ltd. 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Zjartschem 		58
Shanxi Naipu Import and Export Co.,Ltd 		58
career henan chemical co 		58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		58
Hubei Jusheng Technology Co.,Ltd. 		58

View Lastest Price from 2,2'-Dithiodipyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2'-Dithiodipyridine pictures 2024-04-16 2,2'-Dithiodipyridine
2127-03-9
 US $500.00 / KG 1KG 98% 500KG/Month Hebei Yanxi Chemical Co., Ltd.
2,2'-Dithiodipyridine pictures 2023-09-06 2,2'-Dithiodipyridine
2127-03-9
 US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
2,2'-Dithiodipyridine pictures 2023-06-15 2,2'-Dithiodipyridine
2127-03-9
 US $0.00 / GK 1GK 98% 1-10mt Baoji Guokang Bio-Technology Co., Ltd.

2,2'-Dithiodipyridine Spectrum

2,2'-Dithiodipyridine(2127-03-9)MS2,2'-Dithiodipyridine(2127-03-9)1HNMR2,2'-Dithiodipyridine(2127-03-9)13CNMR2,2'-Dithiodipyridine(2127-03-9)IR12,2'-Dithiodipyridine(2127-03-9)Raman

2127-03-9(2,2'-Dithiodipyridine )Related Search:

2,5-PYRIDINEDICARBOXYLIC ACID Diallyldisulfide Dimethyl disulfide THIODIGLYCOLIC ACID 2,2'-Bipyridine
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Pyridine Dibenzyl disulfide 2,6-Lutidine Allicin
2,2'-DITHIOBIS(5-NITROPYRIDINE) 6,6'-DITHIODINICOTINIC ACID Bispyrithione 4,4'-DITHIODIPYRIDINE,4,4Dipyridyldisulfide-(4,4dithiodipyridine) GGKPDLRPCHPPCHYIPRPKPR
2,2'-Dithiodipyridine 4,4'-DIPYRIDYL DISULPHIDE, (4,4'-DITHIODIPYRIDINE) DI[5-(TRIFLUOROMETHYL)-2-PYRIDYL] DISULFIDE

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Bis(2-pyridyl) disulfide Di-2-Pyridyl disulfide Nsc 677438 Pyridine, 2,2'-dithiodi- ALDRITHIOL(TM)-2 2,2'-DITHIODIPYRIDINE 2,2'-DIPYRIDYL DISULPHIDE 2-(PYRIDIN-2-YLDITHIO)PYRIDINE 2-PYRIDINYL DISULFIDE 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] Pyridine, 2,2-dithiobis- 2,2''-DIPYRIDYL DISULFIDE 98+% NSC 94055 2,2'-Disulphanediyldipyridine, 2,2'-Dithiodipyridine Di(pyridin-2-yl) disulphide Aldrithiol(TM)-2 98% 1,2-Di(pyridin-2-yl)disulfide 2-(2-Pyridinyldisulfanyl)pyridine 2,2'-Dipyridinyl disulfide 2,2'-Dithiobis(pyridine) 2,2'-Dithiopyridine 2-Dipyridyl disulfide 2PDS Aldrithol-2 2,2'-Dithiodipyridine, >=99% Bis(pyridin-2-yl) disulfide 2,2μ-Dipyridyl disulfide, 2,2μ-Dithiodipyridine Aldritiol Di(2-pyridyl) persulfide 2,2'-Dithiodipyridine,98% 2,2'-Dithiodipyridin Bis(pyridin-2-yl) disulphide 2,2'- Dipyridil disulfide 2-(pyridin-2-yldisulfanyl)pyridine 2,2'-Bipyridyldisulfide Bis(2-pyridinyl) disulfide 2,2'-Dipyridyl disulfide, 98%, for synthesis 2,2'-DipyridylDisulfide[forPeptideSynthesis]> 2,2'-DIPYRIDYL DISULFIDE FOR SYNTHESIS 2,2'-Dithiodipyridine ISO 9001：2015 REACH 2-(2-Pyridyldisulfanyl)pyridine 9-[(3aS,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-3H-purin-6-one Di(pyridin-2-yl) disulfide 1,2-Di(pyridin-2-yl ALDRITHIOL-2 2,2'-DIPYRIDYL DISULFIDE 2-PDS Dipyridyldisulfide 1,2-Di(pyridin-2-yl)disulfane 2-Pyridyl disulfide Aldrithiol Dithiodipyridine 1,2-Bis(2-pyridinyl) Disulfide 2-Aldrithiol 2,2'-Dithiodipyridine 2127-03-9 21270-03-9 2127-03-09