(E)-ajoene
- CAS No.
- 92284-99-6
- Chemical Name:
- (E)-ajoene
- Synonyms
- (E)-Form;(E)-ajoene;Disulfide, 2-propen-1-yl (1E)-3-(2-propen-1-ylsulfinyl)-1-propen-1-yl
- CBNumber:
- CB52078390
- Molecular Formula:
- C9H14OS3
- Molecular Weight:
- 234.4
- MDL Number:
- MOL File:
- 92284-99-6.mol
| Boiling point | 376.0±42.0 °C(Predicted) |
|---|---|
| Density | 1.181±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform: slightly soluble,Ethyl Acetate: slightly soluble,Methanol: slightly soluble |
| FDA UNII | W36UK64JYA |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
|
(E)-ajoene price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26242 | (E)-Ajoene ≥95% | 92284-99-6 | 1mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 26242 | (E)-Ajoene ≥95% | 92284-99-6 | 5mg | $433 | 2024-03-01 | Buy |
| Cayman Chemical | 26242 | (E)-Ajoene ≥95% | 92284-99-6 | 10mg | $768 | 2024-03-01 | Buy |
(E)-ajoene Chemical Properties,Uses,Production
Description
(E)-Ajoene is a disulfide that has been found in A. sativum and has diverse biological activities. It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml). (E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively). It also inhibits human glutathione reductase and T. cruzi trypanothione reductase when used at a concentration of 200 μM. (E)-Ajoene (25 mg/kg) is neuroprotective in a gerbil model of ischemia-reperfusion injury, reducing reactive astrocytosis and microgliosis in the hippocampal CA1 region.
Uses
E/Z Ajoene functions as an antioxidant, by inhibiting the release of superoxide. Ajoene also has antithrombotic (anti-clotting) properties, which helps prevent platelets in the blood from forming blood clots, potentially reducing the risk of heart disease and stroke in humans.
Definition
ChEBI: (E)-Ajoene is a sulfoxide.
(E)-ajoene Preparation Products And Raw materials
Raw materials
Preparation Products
(E)-ajoene Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Botel Biotechnology Co. Ltd. | 0755-22202135 13316968096 | 1979313431@qq.com | China | 7520 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| Supplier | Advantage |
|---|---|
| Shenzhen Botel Biotechnology Co. Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |