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Levobupivacaine

Levobupivacaine
Levobupivacaine structure
CAS No.
27262-47-1
Chemical Name:
Levobupivacaine
Synonyms
Chirocaine;1-Butyl-N-(2;Levobupivacaine;Levobupivacaine base;1-Butyl-N-(2,6-dimet;Levobupivacaine free base;Levobupivacaine HCl (base);2',6'-Pipecoloxylidide, 1-butyl-, L-(-)-;6-dimethylphenyl)-piperidine-2-carboxamide;Ropivacaine Impurity 40(Ropivacaine EP Impurity A)
CBNumber:
CB52130881
Molecular Formula:
C18H28N2O
Formula Weight:
288.43
MOL File:
27262-47-1.mol

Levobupivacaine Properties

Melting point:
136-137°C
alpha 
D25 -80.9° (c = 5 in methanol)
Boiling point:
430.65°C (rough estimate)
Density 
1.0238 (rough estimate)
refractive index 
1.5700 (estimate)
storage temp. 
Refrigerator
pka
14.85±0.70(Predicted)
EWG's Food Scores
1
FDA UNII
A5H73K9U3W

Levobupivacaine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Local anaesthetic used for epidural and intrathecal anaesthesia.

General Description

Levobupivacaine is the pure “S” enantiomer of bupivacaineand in vivo and in vitro studies confirm that it does notundergo metabolic inversion to R(+) bupivacaine. The pKaof the tertiary nitrogen is 8.09, the same as bupivacaine’s pKa. Levobupivacaine is available in solution for epiduraladministration, peripheral nerve block administration, andinfiltration anesthesia. Clinical trials have shown thatlevobupivacaine and bupivacaine have similar anestheticeffects. Levobupivacaine has lower CNS and cardiotoxicitythan bupivacaine although unintended intravenousinjection when performing nerve blocks may result intoxicity. Racemic bupivacaine is metabolized extensivelywith no unchanged drug found in the urine or feces. Liverenzymes including the CYP3A4 and CYP1A2 isoforms areresponsible for N-dealkylation and 3-hydroxylation oflevobupivacaine followed by glucuronidation or sulfation.

Levobupivacaine Preparation Products And Raw materials

Raw materials

Preparation Products


Levobupivacaine Suppliers

Global( 73)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3014 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 568 55
Hebei Chishuo Biotechnology Co., Ltd.
13292891350 +86 311 66567340
luna@speedgainpharma.com CHINA 1007 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30039 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
whatsapp: +8619930501651 breeduan@crovellbio.com CHINA 2586 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460
faith@widelychemical.com CHINA 743 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23045 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14344 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35434 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58

View Lastest Price from Levobupivacaine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-03 1-Butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide
27262-47-1
US $10.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
2018-12-24 1-Butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide
27262-47-1
US $8.00 / kg 1kg 99% 10tons career henan chemical co
2018-07-23 1-Butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide
27262-47-1
US $10.00 / KG 10ASSAYS 99% 500kg/month Hebei Chishuo Biotechnology Co., Ltd.

27262-47-1(Levobupivacaine)Related Search:


  • Bupivacaine impurity 12/ (S)-(-)-Bupivacaine/Levobupivacaine/Ropivacaine EP Impurity A/(2S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
  • Ropivacaine impurity 1/ Ropivacaine EP Impurity A/(S)-(-)-Bupivacaine/Levobupivacaine/(2S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
  • (2S)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2α-carboxamide
  • 2',6'-Pipecoloxylidide, 1-butyl-, L-(-)-
  • 1-Butyl-N-(2,6-dimet
  • Levobupivacaine base
  • (2S)-1-Butyl-N-(2,6-diMethylphenyl)-2-piperidinecarboxaMide
  • Levobupivacaine HCl (base)
  • Levobupivacaine free base
  • 1-Butyl-N-(2
  • 6-dimethylphenyl)-piperidine-2-carboxamide
  • Ropivacaine Impurity 40(Ropivacaine EP Impurity A)
  • 1-Butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide
  • Chirocaine
  • Levobupivacaine
  • 27262-47-1
  • C18H32ClN2O
  • Inhibitors
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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