ChemicalBook >> CAS DataBase List >>(R)-(+)-Ketorolac
(R)-(+)-Ketorolac
- CAS No.
- 66635-93-6
- Chemical Name:
- (R)-(+)-Ketorolac
- Synonyms
- (1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(+)-Ketorolac;(R)-Ketorolac;(R)-(+)-Ketorolac;Ketorolac R-IsoMer;(R)-Ketorolac [(+)-Ketorolac);(R)-(+)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 1/Ketorolac R-Isomer;(R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid;(R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
- CBNumber:
- CB52226607
- Molecular Formula:
- C15H13NO3
- Molecular Weight:
- 255.27
- MDL Number:
- MFCD00871492
- MOL File:
- 66635-93-6.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:18
| Melting point | 163-170°C |
|---|---|
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D +162 to +178°, c = 1 in methanol |
| FDA UNII | 10A5O25ILE |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
(R)-(+)-Ketorolac price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1654 | R-Ketorolac ≥95% (HPLC) | 66635-93-6 | 5MG | $238 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1654 | R-Ketorolac ≥95% (HPLC) | 66635-93-6 | 25MG | $953 | 2023-06-20 | Buy |
| TRC | K235600 | (R)-Ketorolac | 66635-93-6 | 100mg | $1620 | 2021-12-16 | Buy |
| TRC | K235600 | (R)-Ketorolac | 66635-93-6 | 50mg | $920 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010456 | (+)-KETOROLAC 95.00% | 66635-93-6 | 2MG | $350 | 2021-12-16 | Buy |
(R)-(+)-Ketorolac Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
Definition
ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic keto olac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
Biochem/physiol Actions
R-Ketorolac is potent and selective Rho-family GTPases Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) allosteric inhibitor that modulates downstream GTPase-dependent physiologic responses critical to tumor metastasis. R-ketorolac significantly inhibits ovarian cancer cell adhesion, migration, and invasion.
(R)-(+)-Ketorolac Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 47)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9456 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29321 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 |
View Lastest Price from (R)-(+)-Ketorolac manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-17 | (R)-(+)-Ketorolac
66635-93-6
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2021-10-22 | (R)-(+)-Ketorolac
66635-93-6
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- (R)-(+)-Ketorolac
66635-93-6
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- (R)-(+)-Ketorolac
66635-93-6
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
66635-93-6((R)-(+)-Ketorolac)Related Search:
(S)-Ketorolac
Ketorolac Impurity 48
Ketorolac Impurity 43
Ketorolac Impurity 31
Ketorolac Impurity 24
(5-chloro-1H-pyrrol-2-yl)-phenylmethanone
Ethyl 2-(1H-pyrrol-2-yl)acetate
Ketorolac Related Compound A (20 mg) (5-benzoyl-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2,3-dihydro-1H-pyrrolizine-1-carboxamide)
Ethyl-(5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
Ketorolac Impurity 54
1of4
(R)-(+)-Ketorolac
(R)-Ketorolac
Ketorolac R-IsoMer
Ketorolac impurity 1/Ketorolac R-Isomer
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1R)-
(R)-(+)-Ketorolac ISO 9001：2015 REACH
(R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(R)-Ketorolac [(+)-Ketorolac)
(1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acidQ: What is
(1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the CAS Number of
(1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid Q: What is the storage condition of
(1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(+)-Ketorolac
(R)-Ketorolac,inhibit,Inhibitor,(R) Ketorolac,(R)Ketorolac
66635-93-6
Aromatics
Chiral Reagents
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals