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1-(2,6-Dichlorophenyl)-2-indolinone

Application in Particular Diseases
1-(2,6-Dichlorophenyl)-2-indolinone
1-(2,6-Dichlorophenyl)-2-indolinone structure
CAS No.
15307-86-5
Chemical Name:
1-(2,6-Dichlorophenyl)-2-indolinone
Synonyms
Diclac;Pennsaid;Voltaflan;Rhumalgan;Transfenac;DicloreuMa;DicloMelan;Dielofenac;Diciofenac;Diclofenac
CBNumber:
CB5225367
Molecular Formula:
C14H9Cl2NO
Formula Weight:
278.13
MOL File:
15307-86-5.mol

1-(2,6-Dichlorophenyl)-2-indolinone Properties

Melting point:
156-158°
pka
pKa 4 (Uncertain)
Merck 
14,3081
InChIKey
DCOPUUMXTXDBNB-UHFFFAOYSA-N
CAS DataBase Reference
15307-86-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-(15307-86-5)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
RIDADR  3249
RTECS  AG6310000
HazardClass  6.1(b)
PackingGroup  III
Hazardous Substances Data 15307-86-5(Hazardous Substances Data)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

1-(2,6-Dichlorophenyl)-2-indolinone price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D3748 2-(2,6-Dichloroanilino)phenylacetic Acid >98.0%(GC)(T) 15307-86-5 25g $54 2018-11-22 Buy

1-(2,6-Dichlorophenyl)-2-indolinone Chemical Properties,Uses,Production

Application in Particular Diseases

In Osteoarthritis:
Topical diclofenac in a dimethyl sulfoxide carrier (Pennsaid) is a safe and effective treatment for Osteoarthritis pain. It is thought to act primarily by local inhibition of COX-2 enzymes.

Uses

prostaglandin synthetic inhibitor

Indications

Diclofenac (Voltaren, Cataflam) is approved for use in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, and topically for the treatment treatment of ocular inflammation and actinic keratosis. Diclofenac exhibits approximately equal selectivity for COX-1 and COX-2. The most common adverse reactions are GI disturbances and headache.A reversible elevation of serum transaminases occurs in 15% of patients.

Biological Functions

Diclofenac (Voltaren) is a phenylacetic acid derivative that is a potent inhibitor of COX and that has analgesic, antiinflammatory, and antipyretic effects. Its use is accompanied by side effects similar to those of other NSAIDs. Indications for the drug include rheumatoid arthritis, osteoarthritis, and ophthalmic inflammation (use of an ophthalmic preparation).

1-(2,6-Dichlorophenyl)-2-indolinone Preparation Products And Raw materials

Raw materials

Preparation Products


1-(2,6-Dichlorophenyl)-2-indolinone Suppliers

Global( 192)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21930 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20516 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23982 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20094 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
breeduan@crovellbio.com CHINA 928 58
Wuhan Biocar Bio-Pharm Co., Ltd. 18138772807
86-027-87050469 sales@biocar.cn China 1757 50

View Lastest Price from 1-(2,6-Dichlorophenyl)-2-indolinone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 1-(2,6-Dichlorophenyl)-2-indolinone
15307-86-5
US $7.00 / kg 1kg 99% 100kg career henan chemical co
2019-04-25 Diclofenac
15307-86-5
US $10.00 / kg 1kg 99% 10 Hebei Guanlang Biotechnology Co., Ltd.

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