GADOLINIUM CHLORIDE
- CAS No.
- 10138-52-0
- Chemical Name:
- GADOLINIUM CHLORIDE
- Synonyms
- GdCl3;NSC 174322;inium(III) chL;4-dihydrocoumarin;Gadm(lll) chloride;Trichlorogadolinium;GADOLINIUM CHLORIDE;gadoliniumtrichloride;GADOLINIUM(III) CHLORIDE;gadoliniumchloride(gdcl3)
- CBNumber:
- CB5227053
- Molecular Formula:
- Cl3Gd
- Molecular Weight:
- 263.61
- MDL Number:
- MFCD00011024
- MOL File:
- 10138-52-0.mol
- MSDS File:
- SDS
| Melting point | 609°C |
|---|---|
| Density | 4,52 g/cm3 |
| storage temp. | Hygroscopic, Room Temperature, under inert atmosphere |
| solubility | Water |
| form | powder |
| color | White to off-white |
| Specific Gravity | 4.52 |
| Water Solubility | Soluble in water. |
| Sensitive | Hygroscopic |
| Merck | 14,4326 |
| Stability | hygroscopic |
| CAS DataBase Reference | 10138-52-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | P7082WY76D |
| EPA Substance Registry System | Gadolinium chloride (GdCl3) (10138-52-0) |
GADOLINIUM CHLORIDE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 721905 | Gadolinium(III) chloride solution NMR reference standard, 0.1?mg/mL in D2O (99.9 atom % D), water 1?%, Methanol-13C 0.1?% (99 atom % 13C), NMR tube size 3?mm × 8?in. | 10138-52-0 | 1PKG | $106 | 2024-03-01 | Buy |
| Sigma-Aldrich | 439770 | Gadolinium(III) chloride anhydrous, powder, 99.99% trace metals basis | 10138-52-0 | 5g | $206 | 2024-03-01 | Buy |
| Sigma-Aldrich | 487139 | Gadolinium(III) chloride solution NMR reference standard, water 1?%, DSS 0.1?%, 0.1?mg/mL in D2O (99.9 atom % D), NMR tube size 5?mm × 8?in. | 10138-52-0 | 1EA | $293 | 2024-03-01 | Buy |
| Sigma-Aldrich | 439770 | Gadolinium(III) chloride anhydrous, powder, 99.99% trace metals basis | 10138-52-0 | 25g | $811 | 2024-03-01 | Buy |
| Alfa Aesar | 035736 | Gadolinium(III) chloride, ultra dry, 99.99% (REO) | 10138-52-0 | 5g | $168 | 2024-03-01 | Buy |
GADOLINIUM CHLORIDE Chemical Properties,Uses,Production
Physical Properties
White monoclinic crystal; hygroscopic; density 4.52 g/cm3; melts at 609°C; soluble in water.
Preparation
GdCl3 is prepared by heating gadolinium(III) oxide with excess of ammonium chloride above 200°C:
Gd2O3 + 6NH4Cl→2GdCl3 + 6NH3 + 3H2O
Chemical Properties
Colorless crystals, soluble in water, purities up to 99.9%.
Uses
Gadolinium(III) Chloride is used as chelating agents, which is essential for biomedical applications. It is also employed in the synthesis and nuclear magnetic resonance (NMR) studies of paramagnetic GdPCTA-[12] and GdPCTA-[13] complexes. It plays an important role as contrast agent for magnetic resonance imaging and an macrophage inhibitor.
Uses
GadoliniuM chloride, anhydrous is a calcium-sensing receptor agonist and is known to work by inducing NLRP3 inflammasome activation in bone marrow-derived macrophages.
GdCl3 is used for preparing gadolinium metal.
Definition
ChEBI: Gadolinium trichloride is a gadolinium coordination entity. It has a role as a TRP channel blocker.
Biological Activity
gadolinium chloride is a casr agonist. the casr can activate the nlrp3 inflammasome by increasing intracellular ca2+ and decreasing cellular cyclic amp. thus, casr agonists may serve as a useful tool for exploring nlrp3 inflammasome associated inflammatory diseases such as cryopyrin-associated periodic syndromes, gout and atherosclerosis. in addition, gadolinium chloride has been demonstrated to block trpml channel currents, as well as other transient receptor potential (trp) channels.1. lee gs, subramanian n, kim ai, et al. the calcium-sensing receptor regulates the nlrp3 inflammasome through ca2+ and camp. nature, 2012, 492(7427): 123-127.2. nagata k, zheng l, madathany t, et al. the varitint-waddler (va) deafness mutation in trpml3 generates constitutive, inward rectifying currents and causes cell degeneration. proceedings of the national academy of sciences of the united states of america, 2008, 105(1): 353-358.3. del favero g, florio c, codan b, et al. the stretch-activated channel blocker gd3+ reduces palytoxin toxicity in primary cultures of skeletal muscle cells. chemical research in toxicology, 2012, 25(9): 1912-1920.
storage
Desiccate at RT
GADOLINIUM CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12478 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
View Lastest Price from GADOLINIUM CHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-17 | GADOLINIUM CHLORIDE
10138-52-0
|
US $3.00 / KG | 1KG | 98% | 1kg,5kg,50kg | Career Henan Chemical Co |
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- GADOLINIUM CHLORIDE
10138-52-0
- US $3.00 / KG
- 98%
- Career Henan Chemical Co