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2,3-Dichlorobenzoic acid

2,3-Dichlorobenzoic acid
2,3-Dichlorobenzoic acid structure
CAS No.
50-45-3
Chemical Name:
2,3-Dichlorobenzoic acid
Synonyms
2,3-Dichlorobe;2,3-Dichlorobenzoic;TIMTEC-BB SBB003641;RARECHEM AL BO 0323;2,3-Dichlorbenzoesure;3-Dichlorobenzoic acid;2,3-Dichorobenzoic acid;2,3-dichloro-benzoicaci;2,3-DICHLOROBENZOIC ACID;Lamotrigine EP impurity E
CBNumber:
CB5227477
Molecular Formula:
C7H4Cl2O2
Formula Weight:
191.01
MOL File:
50-45-3.mol

2,3-Dichlorobenzoic acid Properties

Melting point:
168-170 °C(lit.)
Boiling point:
273.68°C (rough estimate)
Density 
1.4410 (rough estimate)
refractive index 
1.4590 (estimate)
form 
neat
Water Solubility 
slightly soluble
BRN 
1946217
InChIKey
QAOJBHRZQQDFHA-UHFFFAOYSA-N
CAS DataBase Reference
50-45-3(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 2,3-dichloro-(50-45-3)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36-24/25
WGK Germany  2
RTECS  DG6475000
HazardClass  IRRITANT
HS Code  29163990
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

2,3-Dichlorobenzoic acid price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 225339 2,3-Dichlorobenzoic acid 97% 50-45-3 10g $76.5 2018-11-13 Buy
Sigma-Aldrich 1356778 Lamotrigine Related Compound B United States Pharmacopeia (USP) Reference Standard 50-45-3 20mg $1212.75 2018-11-13 Buy
TCI Chemical D3319 2,3-Dichlorobenzoic Acid >98.0%(GC)(T) 50-45-3 5g $20 2018-11-22 Buy
TCI Chemical D3319 2,3-Dichlorobenzoic Acid >98.0%(GC)(T) 50-45-3 25g $60 2018-11-22 Buy
Alfa Aesar A10522 2,3-Dichlorobenzoic acid, 98% 50-45-3 10g $61.3 2018-11-13 Buy

2,3-Dichlorobenzoic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

2,3-Dichlorobenzoic acid is the key intermediate for antiepileptic drug Lamotrigine (L173250) and other pharmaceuticals for the treatment of central nervous system (CNS) disorders and disease.

Purification Methods

Aromatic acid impurities (to <0.05%) can be removed via the (±)--methylbenzylamine salt as described for 2,4-dichlorobenzoic acid [Ley & Yates Organic Process Research & Development 12 120 2008.] Crystallise the acid from H2O, aqueous EtOH, or 30% aqueous AcOH and several times from *C6H6, then dry it in vacuo at 40o overnight. The methyl ester has m 35-39o . [Hope & Riley J Chem Soc 123 2478 1923, Lock Monatsh Chem 90 687 1959, Shorter & Mather J Chem Soc 4744 1961, Beilstein 9 II 228, 9 IV 998.]

2,3-Dichlorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products


2,3-Dichlorobenzoic acid Suppliers

Global( 290)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2548 55
Speranza Chemical Co., Ltd.
+8618688942810
+86-755-33122716 sophieliu@speranzachem.com CHINA 171 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20243 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12156 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8430 58

View Lastest Price from 2,3-Dichlorobenzoic acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-20 2,3-Dichlorobenzoic acid
50-45-3
US $1.00 / kg 1kg 95%-99% 100kg career henan chemical co

2,3-Dichlorobenzoic acid Spectrum


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