ChemicalBook >> CAS DataBase List >>6,7,8-TRIMETHOXYCOUMARIN

6,7,8-TRIMETHOXYCOUMARIN

CAS No.
6035-49-0
Chemical Name:
6,7,8-TRIMETHOXYCOUMARIN
Synonyms
BG8;BG 8;BG-8;DIMETHYLFRAXETIN;Di-O-Methylfraxetin;O,O-DIMETHYLFRAXETIN;DIMETHYLFRAXETIN, O,O-;Dimethylfraxetin, >99%;Fraxetin dimethyl ether;6,7,8-TRIMETHOXYCOUMARIN
CBNumber:
CB5237142
Molecular Formula:
C12H12O5
Molecular Weight:
236.22
MDL Number:
MFCD00145039
MOL File:
6035-49-0.mol
Last updated:2025-01-27 09:38:02

6,7,8-TRIMETHOXYCOUMARIN Properties

Melting point 104-105°C
Boiling point 338.68°C (rough estimate)
Density 1.249
refractive index 1.5140 (estimate)
storage temp. 2-8°C
solubility DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming)
form Cryst.
color White to yellow
biological source plant
UNSPSC Code 12352205
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Risk Statements  22
Safety Statements  22-45
HS Code  29322090
NFPA 704
0
2 0

6,7,8-TRIMETHOXYCOUMARIN price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 300192 Dimethylfraxetin 6035-49-0 20mg $462 2021-12-16 Buy
American Custom Chemicals Corporation PXT0000775 DIMETHYLFRAXETIN 95.00% 6035-49-0 5MG $502.7 2021-12-16 Buy
Biorbyt Ltd orb593888 Di-O-methylfraxetin 6035-49-0 20mg $513.4 2021-12-16 Buy
ChemScene CS-7783 Dimethylfraxetin 99.97% 6035-49-0 25mg $552 2021-12-16 Buy
Biorbyt Ltd orb104580 Dimethylfraxetin >98%,Standard References Grade 6035-49-0 20mg $569.5 2021-12-16 Buy
Product number Packaging Price Buy
300192 20mg $462 Buy
PXT0000775 5MG $502.7 Buy
orb593888 20mg $513.4 Buy
CS-7783 25mg $552 Buy
orb104580 20mg $569.5 Buy

6,7,8-TRIMETHOXYCOUMARIN Chemical Properties,Uses,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.

Uses

Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.

Definition

ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.

Biological Activity

Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.

in vitro

At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .

target

Ki: 0.0097 μM (Carbonic anhydrase)

454-73-9
1099-45-2
6035-49-0
Synthesis of 6,7,8-TRIMETHOXYCOUMARIN from 3-FLUORO-5-NITROBENZOTRIFLUORIDE and Ethyl (triphenylphosphoranylidene)acetate

6,7,8-TRIMETHOXYCOUMARIN Preparation Products And Raw materials

Global( 182)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu Yongjian Pharmaceutical Co.,Ltd
+86-0523-80183620 +86-17701422015 982552664@qq.com China 258 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-+86-371-66670886 info@dakenam.com China 19825 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29863 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49732 58

View Lastest Price from 6,7,8-TRIMETHOXYCOUMARIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dimethylfraxetin pictures 2024-11-19 Dimethylfraxetin
6035-49-0
US $35.00-136.00 / mg ≥95% 10g TargetMol Chemicals Inc.
6,7,8-Trimethoxycoumarin pictures 2023-02-24 6,7,8-Trimethoxycoumarin
6035-49-0
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
6,7,8-TRIMETHOXYCOUMARIN  pictures 2021-10-30 6,7,8-TRIMETHOXYCOUMARIN
6035-49-0
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
O,O-DIMETHYLFRAXETIN 6,7,8-TRIMETHOXYCOUMARIN DIMETHYLFRAXETIN, O,O-(RG) DIMETHYLFRAXETIN DIMETHYLFRAXETIN, O,O- 6,7,8-Trimethoxy-2H-1-benzopyran-2-one Di-O-Methylfraxetin Fraxetin dimethyl ether CouMarin, 6,7,8-triMethoxy- 2H-1-Benzopyran-2-one,6,7,8-triMethoxy Dimethylfraxetin 6,7,8-Trimethoxycoumarin Fraxetin dimethylether (6,7,8-OMe) DIMETHYLFRAXETIN, O,O-(P) 6,7,8-TriMethoxy-2H-chroMen-2-one Dimethylfraxetin, >99% 6,7,8-TRIMETHOXYCOUMARIN ISO 9001:2015 REACH BG 8 BG8 BG-8 Dimethylfraxetin, 10 mM in DMSO 6035-49-0 6035-94-0 Coumarins chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract