ChemicalBook >> CAS DataBase List >>D-alpha-Tocopheryl acetate

D-alpha-Tocopheryl acetate

CAS No.
58-95-7
Chemical Name:
D-alpha-Tocopheryl acetate
Synonyms
D-α-Tocopheryl acetate;D-ALPHA-TOCOPHEROL ACETATE;Evipherol;dl-alpha-tocopheryl;α-Tocopherol acetate;D-A-TOCOPHERYL ACETATE;D-α-Tocopherol Acetate;D-alpha-Tocopheryl acetate,98%;Econ;Gevex
CBNumber:
CB5241875
Molecular Formula:
C31H52O3
Molecular Weight:
472.74
MDL Number:
MFCD00072052
MOL File:
58-95-7.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:37

D-alpha-Tocopheryl acetate Properties

Melting point ~25 °C(lit.)
Boiling point 224 °C0.3 mm Hg(lit.)
alpha 3 º (c=2, in ethanol 25 ºC)
Density 0.953 g/mL at 25 °C(lit.)
refractive index n20/D 1.496(lit.)
Flash point >230 °F
storage temp. room temp
solubility Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils, soluble in ethanol (96 per cent).
form oil or semi-solid
color yellow
Odor cryst., odorless
Water Solubility <0.1 g/100 mL at 17 ºC
Merck 14,9495
Stability Stable. Incompatible with strong oxidizing agents.
LogP 12.260 (est)
CAS DataBase Reference 58-95-7(CAS DataBase Reference)
FDA 21 CFR 182.8892
Substances Added to Food (formerly EAFUS) ALPHA-TOCOPHEROL ACETATE
SCOGS (Select Committee on GRAS Substances) alpha-Tocopherol acetate
FDA UNII A7E6112E4N
NIST Chemistry Reference Vitamin e acetate(58-95-7)
EPA Substance Registry System D-.alpha.-Tocopheryl acetate (58-95-7)

SAFETY

Risk and Safety Statements

Hazard statements  H413
Precautionary statements  P273-P501
Safety Statements  24/25
WGK Germany  1
RTECS  GP8280000
HS Code  29362800
NFPA 704
1
1 0

D-alpha-Tocopheryl acetate price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T1157 (+)-α-Tocopherol acetate BioReagent, suitable for insect cell culture, ~1360 IU/g 58-95-7 1g $21.9 2024-03-01 Buy
Sigma-Aldrich T1157 (+)-α-Tocopherol acetate BioReagent, suitable for insect cell culture, ~1360 IU/g 58-95-7 10g $65.1 2024-03-01 Buy
TCI Chemical T2322 D-alpha-Tocopherol Acetate >96.0%(GC) 58-95-7 25g $154 2024-03-01 Buy
Sigma-Aldrich T3001 (+)-α-Tocopherol acetate oil or semi-solid, ~1360 IU/g, semisynthetic 58-95-7 10g $97.7 2024-03-01 Buy
Sigma-Aldrich T3001 (+)-α-Tocopherol acetate oil or semi-solid, ~1360 IU/g, semisynthetic 58-95-7 25g $213 2024-03-01 Buy
Product number Packaging Price Buy
T1157 1g $21.9 Buy
T1157 10g $65.1 Buy
T2322 25g $154 Buy
T3001 10g $97.7 Buy
T3001 25g $213 Buy

D-alpha-Tocopheryl acetate Chemical Properties,Uses,Production

Description

D-alpha-tocopheryl acetate is a natural form of vitamin E and it is stable in terms of shelf life. It is probably the best form for people actively trying to prevent heart disease. It is used in the dietary and clinical supplementations.

References

[1] Jack Challem, User’s Guide to Nutritional Supplements, 2003
[2] M. K. Horwitt, Relative biological values of d-alpha-tocopheryl acetate and all-rac-alpha-tocopheryl acetate in man, The American Society for Clinical Nutrition, 1980, vol. 33, 1856-1860

Chemical Properties

off-white crystalline solid

Uses

α-Tocopherol acetate is the most bioactive of the naturally occurring forms of Vitamin E. Richest sources are green vegetables, grains, and oils, particularly palm, safflower and sunflower oils.

Uses

Used in prevention and treatment of vitamin E deficiencies.

Uses

(+)-α-Tocopherol acetate has been used:

  • as a component of growth medium for retinal cell lines
  • as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables
  • in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano)

Definition

ChEBI: Alpha-Tocopherol acetate is a tocol.

General Description

Odorless off-white crystals. Darkens at 401° F.

Air & Water Reactions

D-alpha-Tocopheryl acetate may be sensitive to prolonged exposure to light and air. . Insoluble in water.

Reactivity Profile

An ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

Flash point data for D-alpha-Tocopheryl acetate are not available. D-alpha-Tocopheryl acetate is probably combustible.

Contact allergens

Tocopherol and tocopheryl acetate are used mainly as antioxidants. Tocopheryl acetate, an ester of tocopherol (vitamin E), can induce allergic contact dermatitis.

Biochem/physiol Actions

α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

108-24-7
59-02-9
58-95-7
Synthesis of D-alpha-Tocopheryl acetate from Acetic anhydride and Vitamin E

D-alpha-Tocopheryl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 297)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10326 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58

View Lastest Price from D-alpha-Tocopheryl acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D-alpha-Tocopheryl acetate pictures 2021-09-29 D-alpha-Tocopheryl acetate
58-95-7
US $0.00 / KG/CTN 5KG 96%-102 1000KG WUHAN FORTUNA CHEMICAL CO., LTD
 D-alpha-Tocopheryl acetate pictures 2019-07-06 D-alpha-Tocopheryl acetate
58-95-7
US $8.00 / kg 1kg 98% 10MT Career Henan Chemical Co
D-alpha-Tocopheryl acetateVitamine E-acetate (2R)-3,4-Dihydro-2,5,7,8-tetraMethyl-2-[(4R,8R)-4,8,12-triMethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate (2R,4'R,8'R)-α-Tocopherol Acetate (2R,4'R,8'R)-α-Tocopheryl Acetate (R,R,R)-α-Tocopheryl Acetate 2,5,7,8-TetraMethyl-2-(4,8,12-triMethyltridecyl)- 6-chroManol Acetate Copherol 12250 EVitaMin E ace 2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetraMethyl-2-[(4R,8R)-4,8,12-triMethyltridecyl]-,6-acetate, (2R)- Vitamin e acetate 93% Oil (+)-ALPHA-TOCOPHEROL ACETATE D-VITAMIN E ACETATE D-TOCOPHEROL ACETATE D-TOCOPHRIN D-ECON D-CONTOPHERON D-ALFACOL D-ALPHA-TOCOPHERYL ACETATE D-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE D-FERTILVIT [2R-[2R*(4R* D-A-TOCOPHEROL ACETATE FROM NATURAL*A-TO COPHEROL IN (+)-A-TOCOPHEROL ACETATE FROM NATURAL*A- TOCOPHEROL (2R,4'R,8'R)-O-Acetyl-alpha-tocopherol-1-benzopyran-6-olacetate [2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4R,8R)-4,8,12-trimethyltridecyl-, acetate, (2R)- VE50%ACETATE D3-RRR-ALPHA-TOCOPHERYLACETATE 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-2H-1-Benzopyran-6-ol 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R(4R,8R)]]- [2R-[2R*(4R8,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,acetate,(+)-6-chromano 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]- 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,acetate,[2R-[2R*(4R*,8R*)]]-2H-1-Benzopyran-6-ol 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)- acetate,[2theta-[2theta(4theta,8theta)]]-yl) aceticacid2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-tridecyl)-chroman-6-ylester Alfacol Combinal E combinale Contopheron Ecofrol Econ E-Ferol Endo E Dompe endoedompe Ephynal acetate ephynalacetate Erevit E-Toplex E-vicotrat Fertilvit Gevex Juvela Spondyvit Tocopherex Tocophrin