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Citalopram

Citalopram
Citalopram structure
CAS No.
59729-33-8
Chemical Name:
Citalopram
Synonyms
CELEXA;cipram;ZD-211;LU-10-171;Ciprarnil;NITALAPRAM;CITALOPRAM;Nitalapram HBr;Citalopram base;(+/-)-CITALOPRAM
CBNumber:
CB5244937
Molecular Formula:
C20H21FN2O
Formula Weight:
324.39
MOL File:
59729-33-8.mol

Citalopram Properties

Melting point:
156-157 °C
Boiling point:
bp0.03 175-181°
Density 
1.18±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
pka
pKa 9.38(H2O) (Uncertain)
CAS DataBase Reference
59729-33-8(CAS DataBase Reference)
FDA UNII
0DHU5B8D6V
NCI Dictionary of Cancer Terms
Celexa; citalopram
NIST Chemistry Reference
Citalopram(59729-33-8)
SAFETY
  • Risk and Safety Statements
RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III

Citalopram Chemical Properties,Uses,Production

Description

Citalopram is a specific serotonin-uptake inhibitor useful in the treatment of depression. In endogenous depression citalopram was reported to be as effective as amitriptyline and mianserin, while being inferior to clomipramine in both endogenous and non-endogenous depression.

Originator

Lundbeck (Denmark)

Uses

scabicide

Uses

antidepressant monoamine oxidase inhibitor (MAOIs)

Definition

ChEBI: A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

brand name

Cipramil

Biological Functions

Citalopram (Celexa) has an elimination half-life of 35 hours and is 80% bound to plasma proteins. Of all of the SSRIs it has the least effect on the cytochrome P450 system and has the most favorable profile regarding drug–drug interactions.

General Description

Citalopram (Celexa) is a racemic mixture and is very SERTselective. The N-monodemethylated compound is slightlyless potent but is as selective. The aryl substituents are importantfor activity. The ether function is important andprobably interacts with the protonated amino group to givea suitable shape for SERT binding.

Biological Activity

Highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake (IC 50 values are 1.8, 8800 and 41000 nM respectively). Has negligible activity at a wide range of receptors and is clinically used as an antidepressant. Also available as part of the Serotonin Uptake Inhibitor Tocriset™ .

Citalopram Preparation Products And Raw materials

Raw materials

Preparation Products


Citalopram Suppliers

Global( 169)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22626 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30045 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23977 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8406 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35434 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 20535 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58
Zhengzhou Alfa Chemical Co.,Ltd
+86 13343822234
sales5@alfachem.cn;sales9@alfachem.cn;sale1@alfachem.cn CHINA 8284 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17852 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132149 58

View Lastest Price from Citalopram manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-12-30 Citalopram
59729-33-8
US $1.00 / KG 1KG 99% 100kg Career Henan Chemical Co
2018-12-25 Citalopram
59729-33-8
US $7.00 / kg 1kg 99% 100kg career henan chemical co

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