PI 828
- CAS No.
- 942289-87-4
- Chemical Name:
- PI 828
- Synonyms
- PI 828;PI 828,PI828;LY 294002, 4′-NH2;LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem;8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one;8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one;2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
- CBNumber:
- CB52455753
- Molecular Formula:
- C19H18N2O3
- Molecular Weight:
- 322.36
- MDL Number:
- MFCD11100185
- MOL File:
- 942289-87-4.mol
PI 828 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 440206 | LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem A cell-permeable LY 294002 4'-amino derivative with enhanced potency against p110α/β/δ/γ. |
942289-87-4 | 5mg | $251 | 2023-01-07 | Buy |
| Cayman Chemical | 21811 | PI-828 ≥98% | 942289-87-4 | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 21811 | PI-828 ≥98% | 942289-87-4 | 5mg | $135 | 2024-03-01 | Buy |
| Cayman Chemical | 21811 | PI-828 ≥98% | 942289-87-4 | 10mg | $235 | 2024-03-01 | Buy |
| Tocris | 2814 | PI828 ≥98%(HPLC) | 942289-87-4 | 1 | $106 | 2021-12-16 | Buy |
PI 828 Chemical Properties,Uses,Production
Definition
ChEBI: 8-(4-aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one is a member of chromones.
General Description
A cell-permeable LY 294002 (Cat. Nos. 440202 & 440204) 4′-amino derivative with enhanced potency against p110α/β/δ/γ (IC50 in nM/-fold increase in potency = 183/2.7-, 98/5.7-, 1227/.5-, and 1967/1.9-, respectively). The molecule has been immobilized on epoxy-containing solid surface via the 4′-amine for binding studies and shown to interact with non-PI3K cellular proteins, such as mTOR, ALDH1, Brd4, GSK3β, and CKIIα.
Biological Activity
PI 3-Kinase inhibitor (IC 50 values are 0.098, 0.183, 0.227 and 1.967 μ M for p110 β , p110 α , p110 δ and p110 γ respectively) that displays higher potency than LY 294002 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride). Can be immobilized onto a solid phase.
storage
Store at +4°C
PI 828 Preparation Products And Raw materials
Raw materials
Preparation Products
PI 828 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9445 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |