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THIQ

THIQ structure

CAS No.: 312637-48-2

Chemical Name:: THIQ

Synonyms: THIQ;(3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidiny;mutant,MC Receptor,inhibit,THIQ,melanocortin,affinity,activity,erectile,selective,eliciting,Melanocortin Receptor,Inhibitor;N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-trazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide;(R)-N-((R)-1-(4-((1H-1,2,4-Triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;(3R)-N-[(1R)-1-[(4-Chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxaMide;3-IsoquinolinecarboxaMide, N-[(1R)-1-[(4-chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-, (3R)-

CBNumber:: CB52459564

Molecular Formula:: C33H41ClN6O2

Molecular Weight:: 589.17

MDL Number:: MFCD09970598

MOL File:: 312637-48-2.mol

Last updated:2023-06-30 15:45:59

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THIQ Properties

Density	1.33±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 250 mg/mL (424.33 mM; Need ultrasonic)
form	Powder
pka	13.82±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

THIQ price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	24303	THIQ ≥95%	312637-48-2	500μg	$99	2021-12-16	Buy
Cayman Chemical	24303	THIQ ≥95%	312637-48-2	1mg	$188	2021-12-16	Buy
Tocris	3032	THIQ ≥95%(HPLC)	312637-48-2	1	$271	2021-12-16	Buy
Usbiological	256927	THIQ	312637-48-2	1mg	$516	2021-12-16	Buy
TRC	C380165	(3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide	312637-48-2	25mg	$5225	2021-12-16	Buy

Product number	Packaging	Price	Buy
24303	500μg	$99	Buy
24303	1mg	$188	Buy
3032	1	$271	Buy
256927	1mg	$516	Buy
C380165	25mg	$5225	Buy

THIQ Chemical Properties,Uses,Production

Uses

Melanocortin 4 receptors play important roles in the regulation of energy homeostasis, eating behavior and sexual functions (1). (3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide is a potent and selective melanocortin 4 receptor agonist (2,3). It inhibits parasympathetic preganglionic neurons in the brainstem and regulates sympathetic and parasympathetic preganglionic neurons.

Biological Activity

Potent and selective melanocortin 4 (MC 4 ) receptor agonist (IC 50 values are 1.2, 761 and 2067 nM for human MC 4 , MC 3 and MC 1 receptors respectively). Enhances intracavernosal pressure and stimulates erectile activity in rats ex copula following systemic administration.

storage

Store at -20°C

THIQ Preparation Products And Raw materials

Raw materials

Preparation Products

THIQ Suppliers

Global( 48)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4121	55
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8018	62
Syntechem Co.,Ltd.	519-88298820 15861130028	info@syntechem.com	China	242	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
BOC Sciences	65
Shanghai Lollane Biological Technology Co.,Ltd.	55
BOC Sciences	65
ShangHai Biochempartner Co.,Ltd	62
Syntechem Co.,Ltd.	58

312637-48-2(THIQ)Related Search:

4-CYCLOHEXYLPIPERIDINE HYDROCHLORIDE 1,2,3,4-Tetrahydroisoquinoline-3-carboxamide 4-(1,2,4-TRIAZOLE-1-YL)-BUTYLAMINE 2-Methylamino-1-morpholin-4-yl-ethanone hydrochloride (R)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID AMIDE

THIQ

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3-IsoquinolinecarboxaMide, N-[(1R)-1-[(4-chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-, (3R)- (3R)-N-[(1R)-1-[(4-Chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxaMide THIQ N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-trazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (R)-N-((R)-1-(4-((1H-1,2,4-Triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidiny mutant,MC Receptor,inhibit,THIQ,melanocortin,affinity,activity,erectile,selective,eliciting,Melanocortin Receptor,Inhibitor 312637-48-2 C33H41ClN6O2