ChemicalBook >> CAS DataBase List >>(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid

CAS No.
204589-82-2
Chemical Name:
(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid
Synonyms
Ezetimibe Impuriry 13;Ezetimibe Impurity 13;Amcenestrant Impurity 10;(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-a...;(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid;(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoic acid;3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoic acid;1-(4-fluorophenyl)-2-oxo-4-[4-(phenylMethoxy)phenyl]-, (3R,4S)-3-Azetidinepropanoic acid;3-[(3R,4S)-1-(4-fluorophenyl)-2-oxo-4-(4-phenylmethoxyphenyl)azetidin-3-yl]propanoic acid;3-Azetidinepropanoic acid, 1-(4-fluorophenyl)-2-oxo-4-[4-(phenylMethoxy)phenyl]-, (3R,4S)-
CBNumber:
CB52462063
Molecular Formula:
C25H22FNO4
Molecular Weight:
419.44
MDL Number:
MFCD13194800
MOL File:
204589-82-2.mol
Last updated:2022-08-26 12:10:16

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Properties

Boiling point 687.4±55.0 °C(Predicted)
Density 1.292
storage temp. 2-8°C
pka 4.53±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H320-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 0503AB 3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoicacid 204589-82-2 1g $597 2021-12-16 Buy
American Custom Chemicals Corporation HCH0036773 3-AZETIDINEPROPANOIC ACID, 1-(4-FLUOROPHENYL)-2-OXO-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)- 95.00% 204589-82-2 5G $909.56 2021-12-16 Buy
American Custom Chemicals Corporation HCH0036773 3-AZETIDINEPROPANOIC ACID, 1-(4-FLUOROPHENYL)-2-OXO-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)- 95.00% 204589-82-2 10G $1334.03 2021-12-16 Buy
AK Scientific 0503AB 3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoicacid 204589-82-2 5g $1374 2021-12-16 Buy
Crysdot CD11168475 3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoicacid 95+% 204589-82-2 5g $972 2021-12-16 Buy
Product number Packaging Price Buy
0503AB 1g $597 Buy
HCH0036773 5G $909.56 Buy
HCH0036773 10G $1334.03 Buy
0503AB 5g $1374 Buy
CD11168475 5g $972 Buy

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Chemical Properties,Uses,Production

Uses

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic Acid is a reagent for the synthesis of antihypercholesterolemia drug Ezetimibe. Also a reagent for the preparation of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235) designed as inhibitor of cholesterol absorption.

(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 55)Suppliers
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Hubei Jusheng Technology Co.,Ltd.
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(3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid 3-Azetidinepropanoic acid, 1-(4-fluorophenyl)-2-oxo-4-[4-(phenylMethoxy)phenyl]-, (3R,4S)- 1-(4-fluorophenyl)-2-oxo-4-[4-(phenylMethoxy)phenyl]-, (3R,4S)-3-Azetidinepropanoic acid 3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoic acid Ezetimibe Impurity 13 3-[(3R,4S)-1-(4-fluorophenyl)-2-oxo-4-(4-phenylmethoxyphenyl)azetidin-3-yl]propanoic acid (3R,4S)-3-Azetidinepropanoic acid,1-(4-fluorophenyl)-2-oxo-4[4(phenylmethoxy)phenyl]-methyl ester (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-a... (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acidQ: What is (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Q: What is the CAS Number of (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Q: What is the storage condition of (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Q: What are the applications of (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Ezetimibe Impuriry 13 N-Nitrosoezetimibe ((4S)-3-[(2R,5S)-2-[(S)-(4-Fluoro-N-nitrosoanilino)-(4-hydroxyphenyl)methyl]-5-(4-fluorophenyl)-5-hydroxy-pentanoyl]-4-phenyl-oxazolidin-2-one) (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoic acid Amcenestrant Impurity 10 204589-82-2