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Cinchonidine

Cinchonidine structure

CAS No.: 485-71-2

Chemical Name:: Cinchonidine

Synonyms: (-)-CINCHONIDINE;(-)-Cinchonidine;Cinchondine;(8s,9r)-cinchonidine;(8a,9R)-Cinchonan-9-ol;L-Cin;A-QUINIDINE;Cinchovatine;CINCHONIDINE;2'-Hydroxy-4'

CBNumber:: CB5246395

Molecular Formula:: C19H22N2O

Molecular Weight:: 294.39

MDL Number:: MFCD00006783

MOL File:: 485-71-2.mol

Last updated:2023-08-30 13:35:17

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Cinchonidine Properties

Melting point	204-206 °C(lit.)
alpha	-115 º (c=1, EtOH)
Boiling point	436.16°C (rough estimate)
Density	1.0863 (rough estimate)
vapor pressure	0Pa at 25℃
refractive index	-107.5 ° (C=1, EtOH)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	0.25g/l
form	Crystalline Powder
pka	5.80, 10.03(at 25℃)
color	White to cream
PH	9 (0.2g/l, H2O, 20℃)
optical activity	[α]23/D 109.2°, c = 1.5 in ethanol
Water Solubility	Insoluble
Sensitive	Light Sensitive
Merck	14,2286
BRN	89690
Stability	Stable, but light-sensitive. Incompatible with strong oxidizing agents.
InChIKey	KMPWYEUPVWOPIM-NAHPKXJFSA-N
LogP	2.68 at 25℃
CAS DataBase Reference	485-71-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	1U622LRA8Z
NIST Chemistry Reference	Cinchonidine(485-71-2)
EPA Substance Registry System	Cinchonan-9-ol, (8.alpha.,9R)- (485-71-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H317-H319

Precautionary statements

P261-P264-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-42/43-36/37/38-20/22-48/22-43-22-63

Safety Statements

22-24/25-36/37-36-26

RIDADR

1544

WGK Germany

RTECS

GD2975000

TSCA

Yes

HazardClass

6.1(b)

PackingGroup

III

HS Code

29392900

Toxicity

LD50 i.p. in rats: 206 mg/kg (Johnson, Poe); LD50 orally in quail: >316 mg/kg (Schafer)

NFPA 704

	1
2		1

Cinchonidine price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	C80407	Cinchonidine 96%	485-71-2	10g	$38.4	2024-03-01	Buy
Sigma-Aldrich	PHL80961	(-)-Cinchonidine phyproof? Reference Substance	485-71-2	100mg	$262	2024-03-01	Buy
Sigma-Aldrich	C80407	Cinchonidine 96%	485-71-2	100g	$138	2024-03-01	Buy
Sigma-Aldrich	44703	(−)-Cinchonidine analyticalstandard	485-71-2	100mg	$45.9	2021-12-16	Buy
TCI Chemical	C0347	Cinchonidine >98.0%(T)	485-71-2	25g	$73	2024-03-01	Buy

Product number	Packaging	Price	Buy
C80407	10g	$38.4	Buy
PHL80961	100mg	$262	Buy
C80407	100g	$138	Buy
44703	100mg	$45.9	Buy
C0347	25g	$73	Buy

Cinchonidine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

antiamebic, antiprotozoal

Uses

Cinchonidine occurs in most varieties of Cinchona bark and is stereoisomeric with Cinchonine. Cinchonidine exhibits Antimalarial properties.

Definition

ChEBI: 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise cinchonidine from aqueous EtOH. For the N-benzylcinchonidinium chloride see above entry in this section. [Beilstein 23 III/IV 2824.]

Cinchonidine Preparation Products And Raw materials

Raw materials

Preparation Products

Esfenvalerate 1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride, (S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE Fosinopril 1,1'-SPIROBIINDANE-7,7'-DIOL

1,1'-Bis(di-tert-butylphosphino)ferrocene N-Benzylcinchonidinium chloride (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE Benazepril (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-PHENOXY

QUININE SULFATE 2-(Dicyclohexylphosphino)biphenyl (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE (R)-7,7'-BIS(DIPHENYLPHOSPHINO)-1,1'-SPIROBIINDANE (S)-1,1'-SPIROBIINDANE-7,7'-DIOL

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Cinchonidine Suppliers

Global( 394)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Guangzhou TongYi biochemistry technology Co.,LTD	+8613073028829	mack@tongyon.com	China	2996	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58

Supplier	Advantage
Guangzhou TongYi biochemistry technology Co.,LTD	58
Hebei Mojin Biotechnology Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Shaanxi Pioneer Biotech Co., Ltd .	58

View Lastest Price from Cinchonidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-30	Cinchonidine 485-71-2	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-06-15	Cinchonidine 485-71-2	US $371.00 / KG	1KG	99%	100kg	Baoji Guokang Bio-Technology Co., Ltd.
2022-05-11	Cinchonidine 485-71-2	US $0.00 / g	10g	99.0%	10tons	Wuhan Godbullraw Chemical Co.,ltd

Cinchonidine
485-71-2
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Cinchonidine
485-71-2
US $371.00 / KG
99%
Baoji Guokang Bio-Technology Co., Ltd.

Cinchonidine
485-71-2
US $0.00 / g
99.0%
Wuhan Godbullraw Chemical Co.,ltd

Cinchonidine Spectrum

Cinchonidine(485-71-2)MS Cinchonidine(485-71-2)¹HNMR Cinchonidine(485-71-2)¹³CNMR Cinchonidine(485-71-2)IR1 Cinchonidine(485-71-2)IR2 Cinchonidine(485-71-2)Raman

485-71-2(Cinchonidine)Related Search:

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(8-alpha,9r)-cinchonan-9-o (8alpha,9theta)-cinchonan-9-o 2-Quinuclidinemethanol, alpha-4-quinolyl-5-vinyl- Cinchonan-9-ol Cinchonan-9-ol, (8alpha,9R)- Cinchovatine Cinchonidinederivedcatalyst {5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)Methanol Cinchonidine, 98.5-101% 100GR Cinchonidine, 98.5-101% 25GR CINCHONIDINE 1-Cinchonidine (-)-Cinchonidine (total base), may cont. up to 5% quinine cinchonidine .base Cinchonidine ,98.5% Cinchonidine,()-Cinchonidine (-)-CINCHONIDINE FOR RESOLUTION OF RACEM (-)-Cinchonidine, 99%, may contain up to 5% quinine (-)-Cinchonidine for resolution of racemates for synthesis CINCHONAN-9-OL,(8,9R)- A-QUINIDINE ALPHA-QUINIDINE (8alpha,9r)-cinchonan-9-ol CINCHONIDINE: CINCHONAN-9-OL,(8,9R)-, Cinchonidine,99% [8α,9R]-Cinchonan-9-ol Cinchonidine, 98.5-101% CINCHONIDINE(RG) L-CINCHONIDINE Cinchonidine (base and/or unspecified salts) 4-Quinolyl-(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol (R)-Quinolin-4-yl[(2S,4S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-yl]methanol (8S,9R)-Cinchonan-9-ol (-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine (R)-[(4S,5R,7S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-quinolin-4-ylmethanol (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol (3alpha,4beta,8alpha,9S)-cinchonan-9-ol (3alpha,9R)-9-hydroxycinchonan-1-ium (4beta,8alpha,9R)-cinchonan-1-ium-9-ol (8alpha,9R)-9-hydroxycinchonan-1-ium (9R)-cinchonan-1-ium-9-ol (9R)-cinchonan-9-ol Quinine Sulphate EP Impurity B L-Cin Cinchonidine, 98%, for synthesis Cinchonidine > Quinine EP Impurity B (R)-Quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol Cinchonidine USP/EP/BP [(2R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol 2'-Hydroxy-4' (8s,9r)-cinchonidine Cinchondine (-)-CINCHONIDINE (-)-Cinchonidine (8a,9R)-Cinchonan-9-ol Cinchonidine (8CI) (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](quinolin-4-yl)methanol (cinchonidine)