1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- CAS No.
- 14542-93-9
- Chemical Name:
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- Synonyms
- WALBORSKY REAGENT;WALBORSKY'S REAGENT;TERT-OCTYLISONITRILE;TERT-OCTYL ISOCYANIDE;2-isocyano-2,4,4-trimethyl-pentan;2-isocyano-2,4,4-triMethylpentane;1,1,3,3-TETRAMETHYLBUTYLISONITRILE;1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE;Pentane, 2-isocyano-2,4,4-trimethyl-;1,1,3,3-Tetramethylbutyl isocyanide,95%
- CBNumber:
- CB5246986
- Molecular Formula:
- C9H17N
- Molecular Weight:
- 139.24
- MDL Number:
- MFCD00000003
- MOL File:
- 14542-93-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1,1,3,3-Tetramethylbutyl isocyanide for synthesis | 8.18105 | 5ml | $219 |
| 1,1,3,3-Tetramethylbutyl isocyanide technical grade | 226491 | 5g | $97 |
| 1,1,3,3-Tetramethylbutyl Isocyanide >95.0%(GC) | T1054 | 1mL | $45 |
| 1,1,3,3-Tetramethylbutyl Isocyanide >95.0%(GC) | T1054 | 5mL | $132 |
| 1,1,3,3-Tetramethylbutyl isocyanide 97% | 114274 | 5g | $138 |
| Boiling point | 55-57 °C11 mm Hg(lit.) |
|---|---|
| Density | 0.794 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 125 °F |
| storage temp. | 2-8°C |
| solubility | insol water; sol common organic solvents |
| form | clear liquid |
| color | Colorless to Almost colorless |
| BRN | 2076559 |
| InChI | InChI=1S/C9H17N/c1-8(2,3)7-9(4,5)10-6/h7H2,1-5H3 |
| InChIKey | YVPXQMYCTGCWBE-UHFFFAOYSA-N |
| SMILES | C(C(C)(C)C)C(C)(C)[N+]#[C-] |
| CAS DataBase Reference | 14542-93-9(CAS DataBase Reference) |
| FDA UNII | 9EVN2N5TVN |
| EPA Substance Registry System | Pentane, 2-isocyano-2,4,4-trimethyl- (14542-93-9) |
| UNSPSC Code | 12352117 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P210-P370+P378 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 10-20/21/22 | |||||||||
| Safety Statements | 23-36/37 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2929 90 00 | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Flam. Liq. 3 | |||||||||
| NFPA 704 |
|
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.18105 | 1,1,3,3-Tetramethylbutyl isocyanide for synthesis | 14542-93-9 | 5ml | $219 | 2025-07-31 | Buy |
| Sigma-Aldrich | 226491 | 1,1,3,3-Tetramethylbutyl isocyanide technical grade | 14542-93-9 | 5g | $97 | 2025-07-31 | Buy |
| TCI Chemical | T1054 | 1,1,3,3-Tetramethylbutyl Isocyanide >95.0%(GC) | 14542-93-9 | 1mL | $45 | 2025-07-31 | Buy |
| TCI Chemical | T1054 | 1,1,3,3-Tetramethylbutyl Isocyanide >95.0%(GC) | 14542-93-9 | 5mL | $132 | 2025-07-31 | Buy |
| Matrix Scientific | 114274 | 1,1,3,3-Tetramethylbutyl isocyanide 97% | 14542-93-9 | 5g | $138 | 2021-12-16 | Buy |
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Chemical Properties,Uses,Production
Chemical Properties
clear colorless liquid
Uses
1,1,3,3-Tetramethylbutyl isocyanide was used in the synthesis of substituted furans and imides.
Preparation
To a stirred solution of 83.0 g (0.528 mole) of N-(l,l,3,3-tetramethylbutyl) formamide in 11 of DMF was added dropwise, under a nitrogen atmosphere, a solution made up of thionyl chloride (40.3 ml, 0.55 mole) dissolved in 150 ml of DMF. The addition was at such a rate that the temperature did not exceed -50°C. After the addition, the cooling bath was removed momentarily to allow the temperature to increase to -35°C and then it was replaced while 118.0 g (1.11 mole) of sodium carbonate (anhydrous grade) was added. Then the cooling bath was removed and the reaction mixture was diluted with ice-cold water in a separatory funnel and then extracted with pentane. The pentane extract was dried over sodium sulfate and concentrated, and the product distilled to yield 68.4 g (93% yield), b.p. 55.5-56.6°C (11 mm). Infrared spectrum (neat) 2110 c m " 1 (s); nmr (neat) 51.08 [s, 9, C(CH3) 2] , 1.43 [t, 6, J = 2Hz, C(CH3) 2] , 1.58 (t, 2, J = 2.3 Hz, CH2).
Application
1,1,3,3-Tetramethylbutyl isocyanide can be added to organometallic reagents to obtain α-metal aldehyde imines, which are used to synthesize useful acyl anion equivalents.
Synthesis
1,1,3,3-Tetramethylbutyl isocyanide is readily available in two steps from 1,1,3,3-tetramethylbutylamine, which is formylated with Formic Acid (86- 90%) followed by dehydration with Dimethylchloromethyleneammonium Chloride (Vilsmeier reagent).
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Preparation Products And Raw materials
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | sale03@alfachem.cn | China | 12830 | 58 |
| BTC pharm India | +918790379245 | banny.janga@btcpharm.com | India | 1262 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49964 | 58 |
| R&D Scientific Inc. | +1-2266000236 | sales@rdscientific.com | Canada | 1929 | 58 |
View Lastest Price from 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-16 | 1,1,3,3-Tetramethylbutyl isocyanide
14542-93-9
|
US $1786.00 / g | 1g | 98 | 500 Kg | R&D Scientific Inc. | |
 |
2021-07-02 | 1,1,3,3-Tetramethylbutyl isocyanide technical grade
14542-93-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 1,1,3,3-Tetramethylbutyl isocyanide
14542-93-9
- US $1786.00 / g
- 98
- R&D Scientific Inc.
-
- 1,1,3,3-Tetramethylbutyl isocyanide technical grade
14542-93-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
