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VX-222

CAS No.
1026785-59-0
Chemical Name:
VX-222
Synonyms
VCH222;VX-222;CS-481;VCH-222;VCH 222;cis-Lomibuvir;VX-222, VCH222;VX222(Lomibuvir);Lomibuvir (VX-222;VX-222 (VCH-222, LoMibuvir)
CBNumber:
CB52501168
Molecular Formula:
C25H35NO4S
Molecular Weight:
445.61
MDL Number:
MFCD18089858
MOL File:
1026785-59-0.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:58

VX-222 Properties

Boiling point 640.5±55.0 °C(Predicted)
Density 1.21
storage temp. Store at -20°C
solubility ≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH
form solid
pka 3.67±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

VX-222 price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26630 Lomibuvir 1026785-59-0 5mg $121 2024-03-01 Buy
Cayman Chemical 26630 Lomibuvir 1026785-59-0 50mg $961 2024-03-01 Buy
Cayman Chemical 26630 Lomibuvir 1026785-59-0 10mg $230 2024-03-01 Buy
Cayman Chemical 26630 Lomibuvir 1026785-59-0 25mg $513 2024-03-01 Buy
TRC V900505 VX-222 1026785-59-0 5mg $270 2021-12-16 Buy
Product number Packaging Price Buy
26630 5mg $121 Buy
26630 50mg $961 Buy
26630 10mg $230 Buy
26630 25mg $513 Buy
V900505 5mg $270 Buy

VX-222 Chemical Properties,Uses,Production

Description

Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).

Uses

VX-222, s a novel, potent and selective inhibitor of HCV polymerase .

Definition

ChEBI: 5-(3,3-dimethylbut-1-ynyl)-3-[(4-hydroxycyclohexyl)-[(4-methylcyclohexyl)-oxomethyl]amino]-2-thiophenecarboxylic acid is a thiophenecarboxylic acid.

target

HCV RNA-dependent RNA polymerase

VX-222 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33349 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58

View Lastest Price from VX-222 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VX-222 pictures 2020-01-09 VX-222
1026785-59-0
US $2.00 / KG 1g 98%min ask Career Henan Chemical Co
  • VX-222 pictures
  • VX-222
    1026785-59-0
  • US $2.00 / KG
  • 98%min
  • Career Henan Chemical Co

VX-222 Spectrum

VX-222 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid VCH 222 VCH222 VCH-222 VX-222, VCH222 VX-222 (VCH-222, LoMibuvir) 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]- Lomibuvir (VX-222, VCH-222) VCH222; VX 222; VCH 222; VCH-222;VX-222 VX222(Lomibuvir) CS-481 Lomibuvir (VX-222 cis-Lomibuvir 1026785-59-0 Inhibitors Inhibitor