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LY 2784544

LY 2784544 structure

CAS No.: 1229236-86-5

Chemical Name:: LY 2784544

Synonyms: Gandotinib (LY2784544);3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine LY 2784544;CS-13;LY2874544;LY 2784544;LY2784544/LY-2784544;LY2784544(gandotinib);Gandotinib LY2784544 LY-2784544;3-(4-Chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[;3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine

CBNumber:: CB52514748

Molecular Formula:: C23H25ClFN7O

Molecular Weight:: 469.94

MDL Number:: MFCD20482143

MOL File:: 1229236-86-5.mol

MSDS File:: SDS

Last updated:2023-05-21 10:59:17

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LY 2784544 Properties

Density	1.45
storage temp.	Store at -20°C
solubility	≥23.5 mg/mL in DMSO; insoluble in H2O; ≥5.65 mg/mL in EtOH with gentle warming and ultrasonic
form	solid
pka	14.12±0.10(Predicted)
NCI Dictionary of Cancer Terms	tucatinib
FDA UNII	ANC71R916O
NCI Drug Dictionary	tucatinib
ATC code	L01EH03

LY 2784544 price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML2567	LY2784544 ≥98% (HPLC)	1229236-86-5	5MG	$148	2024-03-01	Buy
Sigma-Aldrich	SML2567	LY2784544 ≥98% (HPLC)	1229236-86-5	25MG	$285	2024-03-01	Buy
Cayman Chemical	16705	LY2784544 ≥98%	1229236-86-5	1mg	$62	2024-03-01	Buy
Cayman Chemical	16705	LY2784544 ≥98%	1229236-86-5	5mg	$135	2024-03-01	Buy
Cayman Chemical	16705	LY2784544 ≥98%	1229236-86-5	10mg	$239	2024-03-01	Buy

Product number	Packaging	Price	Buy
SML2567	5MG	$148	Buy
SML2567	25MG	$285	Buy
16705	1mg	$62	Buy
16705	5mg	$135	Buy
16705	10mg	$239	Buy

LY 2784544 Chemical Properties,Uses,Production

Uses

LY2784544 is a JAK2 inhibitor. LY2784544 may be used as a potential treatment for patients with myeloproliferative neoplasm.

Definition

ChEBI: Gandotinib is a member of pyridazines.

target

wild-type JAK2

LY 2784544 synthesis

Synthesis of LY 2784544 from 6-chloro-3-(4-chloro-2-fluorobenzyl)-2-Methyl-8-(Morpholin-4-ylMethyl)iMidazo[1,2-b]pyridazine

LY 2784544 Preparation Products And Raw materials

Raw materials

6-chloro-3-(4-chloro-2-fluorobenzyl)-2-Methyl-8-(Morpholin-4-ylMethyl)iMidazo[1,2-b]pyridazine

Preparation Products

LY-2784544 (HCl)

LY 2784544 Suppliers

Global( 150)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jewim Pharmaceutical (Shandong) Co., Ltd.	+86-15552509998 +86-15621883869	liutf@jewim.com.cn	China	251	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58

Supplier	Advantage
Jewim Pharmaceutical (Shandong) Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Biochempartner	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58

View Lastest Price from LY 2784544 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-11-27	Tucatinib；LY 2784544 1229236-86-5	US $0.00 / KG	1KG	99%	20 TONS	Wuhan Senwayer Century Chemical Co.,Ltd
2022-05-14	LY 2784544 1229236-86-5	US $0.00 / g	10g	99.0%	10tons	Wuhan Godbullraw Chemical Co.,ltd
2022-05-11	LY 2784544 1229236-86-5	US $0.00 / KG	0.01KG	99%	1 tons	Wuhan Godbullraw Chemical Co.,ltd

Tucatinib；LY 2784544
1229236-86-5
US $0.00 / KG
99%
Wuhan Senwayer Century Chemical Co.,Ltd

LY 2784544
1229236-86-5
US $0.00 / g
99.0%
Wuhan Godbullraw Chemical Co.,ltd

LY 2784544
1229236-86-5
US $0.00 / KG
99%
Wuhan Godbullraw Chemical Co.,ltd

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1of4

LY2784544(gandotinib) 3-(4-Chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[ 3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine LY 2784544 3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine 3-(4-chloro-2-fluorobenzyl)-2-Methyl-N-(3-Methyl-1H-pyrazol-5-yl)-8-(MorpholinoMethyl)iMidazo[1,2-b]pyridazin-6-aMine LY2784544/LY-2784544 IMidazo[1,2-b]pyridazin-6-aMine, 3-[(4-chloro-2-fluorophenyl)Methyl]-2-Methyl-N-(5-Methyl-1H-pyrazol-3-yl)-8-(4-MorpholinylMethyl)- LY2874544 CS-13 Gandotinib (LY2784544) 3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine LY 2784544 Gandotinib LY2784544 LY-2784544 VEGFR,inhibit,FGFR,LY-2784544,Janus kinase,CD135,FLT3,Cluster of differentiation antigen 135,LY 2784544,Inhibitor,Gandotinib,Fms like tyrosine kinase 3,Vascular endothelial growth factor receptor,JAK,Fibroblast growth factor receptor 1229236-86-5 C23H25ClFN7O Inhibitors JAK STAT Inhibitor JAK/STAT